Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Patrícia Luciana da Costa Lopez"'
Autor:
Natália Schneider, Fabiany da Costa Gonçalves, Fernanda Otesbelgue Pinto, Patrícia Luciana da Costa Lopez, Anelise Bergmann Araújo, Bianca Pfaffenseller, Eduardo Pandolfi Passos, Elizabeth Obino Cirne-Lima, Luíse Meurer, Marcelo Lazzaron Lamers, Ana Helena Paz
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120538 (2015)
Glucocorticoids and immunosuppressive drugs are commonly used to treat inflammatory disorders, such as inflammatory bowel disease (IBD), and despite a few improvements, the remission of IBD is still difficult to maintain. Due to their immunomodulator
Externí odkaz:
https://doaj.org/article/1cc599f80bef4e688de8b5ef9b9fb267
Autor:
Andrea Baldasso-Zanon, Andrew Oliveira Silva, Nayara Franco, Rafael Picon, Guido Lenz, Patrícia Luciana da Costa Lopez, Eduardo Filippi-Chiela
Colorectal cancer (CRC) is the third most common and deadliest cancers globally. The primary chemotherapy used for treating CRC is a co-treatment of 5-fluoruracil (5FU) and Oxaliplatin (OXA). In this study, we investigated the cellular mechanisms tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0c2cec588e3650c47531c044e383d0e
https://doi.org/10.21203/rs.3.rs-2975359/v1
https://doi.org/10.21203/rs.3.rs-2975359/v1
Autor:
Ricardo Iserhard, Emily Ferreira Salles Pilar, Francine Hehn, Sídia Maria Callegari-Jacques, Paula Ferst, Fernanda Visioli, Patrícia Luciana da Costa Lopez, Eduardo Filippi-Chiela
Less than 15% of patients with esophageal squamous cell carcinoma (ESCC) survive five years after the diagnosis. A better understanding of the biology of these tumors and the development of clinical biomarkers is necessary. Autophagy is a physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ea4953fe9b7fcb356fc1a1afd61b35
https://doi.org/10.21203/rs.3.rs-2821223/v1
https://doi.org/10.21203/rs.3.rs-2821223/v1
Autor:
Mayumi Zanotta Oyama, Francine Hehn de Oliveira, Emilly Schlee Villodre, Gustavo Sevlever, Guido Lenz, Alejandra Guberman, Karina Bettega Felipe, Patrícia Luciana da Costa Lopez, Claudia Solari
Publikováno v:
Biochemical and Biophysical Research Communications. 517:324-329
Induced pluripotent stem cells (iPSC) have a great potential, but their clinical application depends on finding strategies to abolish their tumorigenic potential. The use of Oct4, Sox2, Klf4, c-Myc and Nanog to generate iPSC demonstrated the already
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f067774de85a5d44d2565fc10141b0f6
https://doi.org/10.1016/j.bbrc.2019.07.064
https://doi.org/10.1016/j.bbrc.2019.07.064
Autor:
Fábio Klamt, Marienela Buendia, Ana Lucia Abujamra, Viviane Rösner Almeida, Lauro José Gregianin, André T Brunetto, Caroline Brunetto de Farias, Algemir Lunardi Brunetto, Patrícia Luciana da Costa Lopez, Rafael Roesler, Igor Araújo Vieira
Publikováno v:
Molecular Neurobiology. 54:7610-7619
Neuroblastoma (NB) is the most common extracranial solid childhood tumor accounting for around 15% of pediatric cancer deaths and most probably originates from a failure in the development of embryonic neural crest cells. Retinoids can inhibit the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418abf79fceff9a8808a52d5701ed438
https://doi.org/10.1007/s12035-016-0250-3
https://doi.org/10.1007/s12035-016-0250-3
Autor:
Patrícia Luciana da Costa Lopez, Guido Lenz, Emilly Schlee Villodre, Karina Bettega Felipe, Andrew Oliveira Silva
Publikováno v:
Tumor Biology. 37:13743-13749
Although cancer is a chronic disease, most of the in vitro experiments to assess the effectiveness of intervention are performed in hours or a few days. Moreover, none of the available methodologies to measure cell proliferation are adapted to provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351c8341797e917d0ff425d37ff9b45a
https://doi.org/10.1007/s13277-016-5255-z
https://doi.org/10.1007/s13277-016-5255-z
Autor:
Carla Vaz Ferreira, Shana de Souto Weber, Simone Magagnin Wajner, Ana Luiza Maia, Edna Teruko Kimura, Mirian Romitti, Helena Cecin Rohenkohl, Cesar Seigi Fuziwara, Rafaela Vanin Pinto Ribeiro, Lucieli Ceolin, Patrícia Luciana da Costa Lopez
Publikováno v:
Endocrine-Related Cancer. 23:135-146
Type 3 deiodinase (DIO3, D3) is reactivated in human neoplasias. Increased D3 levels in papillary thyroid carcinoma (PTC) have been associated with tumor size and metastatic disease. The objective of this study is to investigate the signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f61ed647ccead2918da9e18d48606b
https://doi.org/10.1530/erc-15-0162
https://doi.org/10.1530/erc-15-0162
Autor:
Patrícia Luciana da Costa Lopez, Carol J. Thiele, Caroline Brunetto de Farias, Pamela Rossi Menegotto, Igor Araújo Vieira, Lauro José Gregianin, Ana Lucia Abujamra, Bárbara Kunzler Souza, Nathalia Kersting, André T Brunetto, Rafael Roesler, Algemir Lunardi Brunetto
There is an urgent need for advances in the treatment of Ewing sarcoma (EWS), an aggressive childhood tumor with possible neuroectodermal origin. Inhibition of histone deacetylases (HDAC) can revert aberrant epigenetic states and reduce growth in dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bf149a137a00e6f7654032bcc116c0
Autor:
Lauro José Gregianin, Rafael Roesler, Ana Lucia Abujamra, André T Brunetto, Nathalia Kersting, Patrícia Luciana da Costa Lopez, Pamela Rossi Menegotto, Caroline Brunetto de Farias, Carol J. Thiele, Igor Araújo Vieira, Algemir Lunardi Brunetto, Bárbara Kunzler Souza
Publikováno v:
Molecular neurobiology. 55(9)
There is an urgent need for advances in the treatment of Ewing sarcoma (EWS), an aggressive childhood tumor with possible neuroectodermal origin. Inhibition of histone deacetylases (HDAC) can revert aberrant epigenetic states and reduce growth in dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948b6a705ecf437d1b6f630e4cd92544
https://pubmed.ncbi.nlm.nih.gov/29397557
https://pubmed.ncbi.nlm.nih.gov/29397557
Autor:
Emilly Schlee Villodre, Franciele Cristina Kipper, Guido Lenz, Patrícia Luciana da Costa Lopez, Andrew Oliveira Silva
Publikováno v:
Molecular neurobiology. 55(5)
Glioblastoma (GBM) is an aggressive brain tumor with temozolomide (TMZ)-based chemotherapy as the main therapeutic strategy. Doxorubicin (DOX) is not used in gliomas due to its low bioavailability in the brain; however, new delivery strategies and lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c4b8d8c1bead01b30a2f132d0aa9ea
https://pubmed.ncbi.nlm.nih.gov/28612256
https://pubmed.ncbi.nlm.nih.gov/28612256