Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrícia Gomes Wessler"'
Autor:
Danielle Celso, Amanda Kunz Godoi, Gustavo Antunes Mastella, Arlindo da Costa Afonso, Patrícia Gomes Wessler, Alexandra I. Zugno, Felipe D. Pacheco, Lara Canever, Isabela Hubbe, João Quevedo
Publikováno v:
International Journal of Developmental Neuroscience. 79:49-53
Early childhood schizophrenia (COS) is a rare condition and has no established animal model to test new treatments. Previous studies have shown that repeated doses of 25 mg/kg ketamine produce schizophrenia-like changes in adult male Wistar rats, but
Autor:
Alexandra I. Zugno, Felipe D. Pacheco, Gustavo Antunes Mastella, Louyse S. Damazio, Tamires Pavei Macan, João Quevedo, Patrícia Gomes Wessler, Alexandra S. Heylmann, Lara Canever, Amanda V. Steckert, Thayara H. Pedro, Octacílio P. Calixto, Josiane Budni, Patrícia F. Schuck, Flávio P. Pereira, Mariana B. Oliveira
Publikováno v:
Journal of Psychiatric Research. 81:23-35
Recent studies have shown benefits for the supplementation of folic acid in schizophrenic patients. The aim of this study was to evaluate the effects of folic acid addition on adult rats, over a period of 7 or 14 days. It also sets out to verify any
Autor:
Gustavo Antunes Mastella, Karoline V. Freitas, Patrícia Gomes Wessler, Flávia da Rosa Silveira, Alexandra S. Heylmann, Emilio L. Streck, Alexandra I. Zugno, Lara Canever, Mariana B. Oliveira, Adalberto A. Castro, Felipe D. Pacheco, João Quevedo, Josiane Budni, Cinara Ludwig Gonçalves
Publikováno v:
Metabolic Brain Disease. 30:1043-1053
Maternal deprivation (MD) appears to be one of the environmental factors involved in the pathophysiology of schizophrenia. A widely used animal model of the schizophrenia involves the administration of ketamine, a dissociative anesthetic, NMDA recept
Autor:
Lara Canever, Helder Chipindo, Gustavo Antunes Mastella, Luiza W. Kist, Flávia da Rosa Silveira, Josiane Budni, Louyse S. Damazio, Alexandra I. Zugno, Maurício Reis Bogo, João Quevedo, Mariana B. Oliveira, Clarissa Severino Gama, Patrícia Gomes Wessler, Alexandra S. Heylmann, Adalberto A. Castro
Publikováno v:
Life Sciences. 121:65-69
Aims Schizophrenia is a debilitating neurodevelopmental disorder that is associated with dysfunction in the cholinergic system. Early prevention is a target of treatment to improve long-term outcomes. Therefore, we evaluated the preventive effects of
Autor:
Andreza L. Cipriano, Josiane Budni, M. B. de Oliveira, João Quevedo, F. da Rosa Silveira, Renata D. De Luca, Patrícia Gomes Wessler, Alexandra S. Heylmann, Ana Maria Jesuino Volpato, Pedro F. Deroza, Alexandra I. Zugno, I. M. de Miranda, G. Antunes Mastella
Publikováno v:
Neuroscience. 248:252-260
Maternal deprivation has been associated with physiological and developmental changes that may be related to an increased risk for childhood and adult neuropsychiatric diseases. A growing number of studies demonstrated the importance of childhood exp
Omega-3 prevents behavior response and brain oxidative damage in the ketamine model of schizophrenia
Autor:
Amanda V. Steckert, Alexandra I. Zugno, Clarissa Severino Gama, F. da Rosa Silveira, Gustavo Antunes Mastella, H.L. Chipindo, Josiane Budni, Patrícia Gomes Wessler, Patrícia F. Schuck, Alexandra S. Heylmann, M. B. de Oliveira, João Quevedo, A.R. Binatti, Bruna Panizzutti, Ana Maria Jesuino Volpato, S.G. Maravai
Publikováno v:
Neuroscience. 259
Supplementation with omega-3 has been identified as an adjunctive alternative for the treatment of psychiatric disorders, in order to minimize symptoms. Considering the lack of understanding concerning the pathophysiology of schizophrenia, the presen