Renal claudin-14 expression is not required for regulating Mg2+ balance in mice

Autor: Wouter H van Megen, Christy Hui Lin Lee, Per Svenningsen, Rebecca Siu Ga Tan, Patrícia G Ferreira, R. Todd Alexander, Henrik Dimke

Publikováno v: American Journal of Physiology : Renal Physiology, 320, 5, pp. F897-F907
American Journal of Physiology : Renal Physiology, 320, F897-F907
Ferreira, P G, van Megen, W H, Tan, R S G, Lee, C H L, Svenningsen, P, Alexander, R T & Dimke, H 2021, ' Renal claudin-14 expression is not required for regulating Mg 2+ balance in mice ', American journal of physiology. Renal physiology, vol. 320, no. 5, pp. F897-F907 . https://doi.org/10.1152/ajprenal.00590.2020

Item does not contain fulltext The kidneys play a crucial role in maintaining Ca(2+) and Mg(2+) homeostasis by regulating these minerals' reabsorption. In the thick ascending limb of Henle's loop (TAL), Ca(2+) and Mg(2+) are reabsorbed through the ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea885566587d7d86d8d9e39cdb1fb54
https://doi.org/10.1152/ajprenal.00590.2020

Gentamicin Inhibits Ca(2+) Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor-Claudin-14 Pathway

Autor: Wouter H. van Megen, Megan R. Beggs, Sung-Wan An, Patrícia G. Ferreira, Justin J. Lee, Matthias T. Wolf, R. Todd Alexander, Henrik Dimke

Publikováno v: Journal of the American Society of Nephrology, 33, 547-564
van Megen, W, Beggs, M, An, S-W, Ferreira, P, Lee, J, Wolf, M, Alexander, R T & Dimke, H 2022, ' Gentamicin Inhibits Ca2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor-Claudin-14 Pathway ', Journal of the American Society of Nephrology, vol. 33, no. 3, pp. 547-564 . https://doi.org/10.1681/ASN.2021030392
Journal of the American Society of Nephrology, 33, 3, pp. 547-564
J Am Soc Nephrol

Contains fulltext : 249144.pdf (Publisher’s version ) (Closed access) BACKGROUND: Treatment with the aminoglycoside antibiotic gentamicin can be associated with severe adverse effects, including renal Ca(2+) wasting. The underlying mechanism is unk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85c8782598a72a8a947bfa8289b005f
https://doi.org/10.1681/ASN.2021030392