Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patrícia A. T. Martins"'
Autor:
Maria João Moreno, Hugo A. L. Filipe, Susana V. P. Cunha, Cristiana V. Ramos, Patrícia A. T. Martins, Biebele Abel, Luís M. S. Loura, Suresh V. Ambudkar
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 174 (2023)
The transport of drugs by efflux transporters in biomembranes limits their bioavailability and is a major determinant of drug resistance development by cancer cells and pathogens. A large number of chemically dissimilar drugs are transported, and des
Externí odkaz:
https://doaj.org/article/254c0ff6fc114e2ea036bbb3622ea762
Autor:
Ricardo C. deAbreu, Cristiana V. Ramos, Clarissa Becher, Miguel Lino, Carlos Jesus, Paula A. daCosta Martins, Patrícia A. T. Martins, Maria João Moreno, Hugo Fernandes, Lino Ferreira
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Small extracellular vesicles (sEVs), through their natural ability to interact with biological membranes and exploit endogenous processing pathways to convey biological information, are quintessential for the delivery of therapeutically rele
Externí odkaz:
https://doaj.org/article/4484de6cbf564657ba2c609e2c3bab5b
Autor:
Cristiana L. Pires, Catarina Praça, Patrícia A. T. Martins, Ana L. M. Batista de Carvalho, Lino Ferreira, Maria Paula M. Marques, Maria João Moreno
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1563 (2021)
Caco-2 monolayers are a common in vitro model used to evaluate human intestinal absorption. The reference protocol requires 21 days post-seeding to establish a stable and confluent cell monolayer, which is used in a single permeability assay during t
Externí odkaz:
https://doaj.org/article/1c9b44e53e6b428289ca0f775d56e471
Publikováno v:
Journal of Chemical Education. 99:1488-1496
Autor:
Diogo A. Pereira, Alexandre D. Silva, Patricia A. T. Martins, Ana P. Piedade, Dmitro Martynowych, David Veysset, Maria João Moreno, Carlos Serpa, Keith A. Nelson, Luis G. Arnaut
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Target delivery of large foreign materials to cells requires transient permeabilization of the cell membrane without toxicity. Giant unilamellar vesicles (GUVs) mimic the phospholipid bilayer of the cell membrane and are also useful drug del
Externí odkaz:
https://doaj.org/article/74c5f6fd006045a8b42db599ba9f2875