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Micrococcin cysteine-to-thiazole conversion through transient interactions between a scaffolding protein and two modification enzymes.

Autor: Calvopina-Chavez DG; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602., Bursey DM; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602., Tseng YJ; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Patil LM; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Bewley KD; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143.; Currently at: Genentech Inc, San Francisco, CA 94080., Bennallack PR; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602.; Currently at: Werfen North America, Bedford, MA 01730., McPhie JM; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Wagstaff KB; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Daley A; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Miller SM; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Moody JD; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Price JC; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602., Griffitts JS; Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 23. Date of Electronic Publication: 2023 Oct 23.