Zobrazeno 1 - 10
of 479
pro vyhledávání: '"Patient-derived xenograft (PDX)"'
Autor:
Xiu-Ya Chan, Kai-Ping Chang, Chia-Yu Yang, Chiao-Rou Liu, Chu-Mi Hung, Chun-Chueh Huang, Hao-Ping Liu, Chih-Ching Wu
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Background Oral cancer accounts for 2% of cancer-related deaths globally, with over 90% of cases being oral cavity squamous cell carcinomas (OSCCs). Approximately 50% of patients with OSCC succumb to the disease within 5 years, primarily due
Externí odkaz:
https://doaj.org/article/386a2840509f4202adb4b09360e0f660
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ca24dd89f8ba4051bf9e01d17f505417
Publikováno v:
Biomedical Journal, Vol 47, Iss 3, Pp 100744- (2024)
Background: Given the heterogeneity and high mortality associated with metastatic soft tissue sarcoma, this study aims to evaluate the therapeutic efficacy of combining 177Lu-FAPI-46 with Pazopanib against this malignancy. Methods: Patient-derived xe
Externí odkaz:
https://doaj.org/article/f83c372728994ea3895513cc77e1168e
Autor:
Dafu Chen, Chengyue Lei, Weifeng Liu, Meiyu Shao, Meizhou Sun, Jianxun Guo, Jingjing Cao, Jing-Jun Nie, Peng Luo, Yuwen Luo, Bingran Yu, Renxian Wang, Shun Duan, Fu-Jian Xu
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 376-385 (2023)
miRNAs are important regulators of gene expression and play key roles in the development of cancer, including osteosarcoma. During the development of osteosarcoma, the expression of miR-22 is significantly downregulated, making miR-22 as a promising
Externí odkaz:
https://doaj.org/article/d71c6954a0354392af967a141fd0de0b
Autor:
Seol Hwa Shin, Eun Jin Ju, Jin Park, Eun Jung Ko, Mi Ri Kwon, Hye Won Lee, Ga Won Son, Yun-Yong Park, Yeon Joo Kim, Si Yeol Song, Sangkwang Lee, Beom Seok Seo, Jin-A Song, Sangbin Lim, Doohwan Jung, Sunyoung Kim, Hyangsook Lee, Seok Soon Park, Seong-Yun Jeong, Eun Kyung Choi
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The B7-H3 protein, encoded by the CD276 gene, is a member of the B7 family of proteins and a transmembrane glycoprotein. It is highly expressed in various solid tumors, such as lung and breast cancer, and has been associated with
Externí odkaz:
https://doaj.org/article/143e4bef18f04341876c841b9c2dc509
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-24 (2023)
Abstract Background Despite recent advances in research, there are still critical lacunae in our basic understanding of the cause, pathogenesis, and natural history of many cancers, especially heterogeneity in patient response to drugs and mediators
Externí odkaz:
https://doaj.org/article/7c439c97054f4a7686f41d0c19c3919d
Publikováno v:
Current Research in Biotechnology, Vol 7, Iss , Pp 100228- (2024)
Traditional Chinese Medicine (TCM) introduces a potentially effective strategy in the realm of cancer therapy, whereas network pharmacology provides a reliable mechanism for clarifying the complex interplay between active constituents and their corre
Externí odkaz:
https://doaj.org/article/f46835d56d4c43e5b0b2ab212dfc93c0
Autor:
Daniel J. Turnham, Manisha S. Mullen, Nicholas P. Bullock, Kathryn L. Gilroy, Anna E. Richards, Radhika Patel, Marcos Quintela, Valerie S. Meniel, Gillian Seaton, Howard Kynaston, Richard W. E. Clarkson, Toby J. Phesse, Peter S. Nelson, Michael C. Haffner, John N. Staffurth, Helen B. Pearson
Publikováno v:
Cells, Vol 13, Iss 8, p 673 (2024)
As the treatment landscape for prostate cancer gradually evolves, the frequency of treatment-induced neuroendocrine prostate cancer (NEPC) and double-negative prostate cancer (DNPC) that is deficient for androgen receptor (AR) and neuroendocrine (NE)
Externí odkaz:
https://doaj.org/article/1e39ec5e9d2d4ad899c5d22bfe802b4a
Autor:
Yasuyuki Saito, Rie Iida-Norita, Tania Afroj, Alaa Refaat, Daisuke Hazama, Satomi Komori, Shinya Ohata, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yohei Funakoshi, Yu-Ichiro Koma, Yoji Murata, Kimikazu Yakushijin, Hiroshi Matsuoka, Hironobu Minami, Hiroshi Yokozaki, Markus G. Manz, Takashi Matozaki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment and are considered potential targets for cancer immunotherapy. To examine the antitumor effects of agents targeting human TAMs in vivo, we here established preclinical tum
Externí odkaz:
https://doaj.org/article/784d3137dd2e455384e08104a9ce3615
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/b6e9763327414aa79afd9571b92ca5cd