Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Patient-derived tumor organoids"'
Autor:
Lilian Roth, Linda Huynh-Russo, Laura Heeb, Sima Ulugöl, Rafael Freire Dos Santos, Eva Breuer, Udo Ungethüm, Martina Haberecker, Chantal Pauli, Viktor Koelzer, Kuno Lehmann, Anurag Gupta
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Multimodal therapy for peritoneal metastasis (PM) including cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provides long-term survival in highly selected colorectal cancer patients. Mechanisms behind HIPEC
Externí odkaz:
https://doaj.org/article/fad11af395664b6181c3d0cec33526fd
Autor:
David A. Close, Paul A. Johnston
Publikováno v:
SLAS Discovery, Vol 30, Iss , Pp 100201- (2025)
Patient derived tumor organoid (PDTO) models retain the structural, morphological, genetic, and clonal heterogeneity of the original tumors. The ability to efficiently generate, expand, and biobank PDTOs has the potential to make the clinical diversi
Externí odkaz:
https://doaj.org/article/b363b1add6bd4a7d82d47a7a7127e6de
Autor:
Lucie Thorel, Jordane Divoux, Justine Lequesne, Guillaume Babin, Pierre-Marie Morice, Romane Florent, Guillaume Desmartin, Lucie Lecouflet, Chloé Marde Alagama, Alexandra Leconte, Bénédicte Clarisse, Mélanie Briand, Roman Rouzier, Léopold Gaichies, Sandrine Martin-Françoise, Jean-François Le Brun, Christophe Denoyelle, Nicolas Vigneron, Corinne Jeanne, Cécile Blanc-Fournier, Raphaël Leman, Dominique Vaur, Martin Figeac, Matthieu Meryet-Figuiere, Florence Joly, Louis-Bastien Weiswald, Laurent Poulain, Enora Dolivet
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Ovarian cancer is the first cause of death from gynecological malignancies mainly due to development of chemoresistance. Despite the emergence of PARP inhibitors, which have revolutionized the therapeutic management of some of the
Externí odkaz:
https://doaj.org/article/088b590c02d14c37987eaddfddc2217f
Autor:
Peter D. Haughton, Wisse E. Haakma, Sven van Kempen, Emma J. de Ruiter, Stefan M. Willems, Patrick W.B. Derksen
Publikováno v:
Oral Oncology Reports, Vol 10, Iss , Pp 100394- (2024)
Keratin proteins are intermediate filaments that provide mechanical support and guide a plethora of important functions in epithelial cells. Although Keratins can be effectively used to characterize and differentiate cell lineages in many epithelia,
Externí odkaz:
https://doaj.org/article/6f72331067d14bde9f2b95b30bc56274
Autor:
Lucie Thorel, Pierre-Marie Morice, Hippolyte Paysant, Romane Florent, Guillaume Babin, Cécilia Thomine, Marion Perréard, Edwige Abeilard, Florence Giffard, Emilie Brotin, Christophe Denoyelle, Céline Villenet, Shéhérazade Sebda, Mélanie Briand, Florence Joly, Enora Dolivet, Didier Goux, Cécile Blanc-Fournier, Corinne Jeanne, Marie Villedieu, Matthieu Meryet-Figuiere, Martin Figeac, Laurent Poulain, Louis-Bastien Weiswald
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background In the era of personalized medicine, the establishment of preclinical models of cancer that faithfully recapitulate original tumors is essential to potentially guide clinical decisions. Methods We established 7 models [4 cell line
Externí odkaz:
https://doaj.org/article/fcc6d93e6e1648e1ac7194108ee99a59
Autor:
Jordane Divoux, Romane Florent, Margaux Jacobs, Justine Lequesne, Jean-Michel Grellard, Chankannira San, Sara Grossi, Katia Kerdja, Bénédicte Clarisse, Gwenaelle Boudier, François Cherifi, Mélanie Briand, Enora Dolivet, Alisson Johnson, Brice Dubois, Valentin Harter, Joëlle Lacroix, Charlotte Raboutet, Brigitte Marie, Nathalie Rousseau, Cécile Blanc-Fournier, Dominique Vaur, Martin Figeac, Laurent Poulain, Louis-Bastien Weiswald, George Emile
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly due to locally advanced tumor and high risk of metastasis. The current neoadjuvant
Externí odkaz:
https://doaj.org/article/ca31ade11a73463e975df48ff00e460c
Autor:
Marion Perréard, Romane Florent, Jordane Divoux, Jean-Michel Grellard, Justine Lequesne, Mélanie Briand, Bénédicte Clarisse, Nathalie Rousseau, Esther Lebreton, Brice Dubois, Valentin Harter, Audrey Lasne-Cardon, Julien Drouet, Alisson Johnson, Anne-Laure Le Page, Céline Bazille, Corinne Jeanne, Martin Figeac, Nicolas Goardon, Dominique Vaur, Emmanuel Micault, Maxime Humbert, Juliette Thariat, Emmanuel Babin, Laurent Poulain, Louis-Bastien Weiswald, Vianney Bastit
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Radiotherapy is one of the cornerstones of the treatment of Head and Neck Squamous Cell Carcinomas (HNSCC). However, radioresistance is associated with a high risk of recurrence. To propose strategies (such as combinations with dr
Externí odkaz:
https://doaj.org/article/157ee7a47bcf42fa8e443bc19ac95f31
Autor:
Haijiang Dong, Zequn Li, Suchen Bian, Guangyuan Song, Wenfeng Song, Mingqi Zhang, Haiyang Xie, Shusen Zheng, Xuxu Yang, Tiefeng Li, Penghong Song
Publikováno v:
Bioactive Materials, Vol 18, Iss , Pp 164-177 (2022)
A personalized medication regimen provides precise treatment for an individual and can be guided by pre-clinical drug screening. The economical and high-efficiency simulation of the liver tumor microenvironment (TME) in a drug-screening model has hig
Externí odkaz:
https://doaj.org/article/ad9eacc2a49a4e6f9bea81d52f66b47b
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Akademický článek
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