Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Patience K. Kiyuka"'
Autor:
Lawrence T Wang, Lais S Pereira, Patience K Kiyuka, Arne Schön, Neville K Kisalu, Rachel Vistein, Marlon Dillon, Brian G Bonilla, Alvaro Molina-Cruz, Carolina Barillas-Mury, Joshua Tan, Azza H Idris, Joseph R Francica, Robert A Seder
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010133 (2021)
Combinations of monoclonal antibodies (mAbs) against different epitopes on the same antigen synergistically neutralize many viruses. However, there are limited studies assessing whether combining human mAbs against distinct regions of the Plasmodium
Externí odkaz:
https://doaj.org/article/d385b3ce72a7496ba9242f6f5b20828b
Autor:
Joyce U. Nyiro, Patience K. Kiyuka, Martin N. Mutunga, Charles J. Sande, Patrick K. Munywoki, J. Anthony G. Scott, D. James Nokes
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Severe disease associated with respiratory syncytial virus (RSV) infection occurs predominantly among infants under 6 months of age. Vaccines for prevention are in clinical development. Assessment of the vaccine effectiveness in large epi
Externí odkaz:
https://doaj.org/article/1c15024ace164561ac81a17f2ead182d
Autor:
Joyce U Nyiro, Ivy K Kombe, Charles J Sande, James Kipkoech, Patience K Kiyuka, Clayton O Onyango, Patrick K Munywoki, Timothy M Kinyanjui, D James Nokes
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177803 (2017)
Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract disease in early life and a target for vaccine prevention. Data on the age-prevalence of RSV specific antibodies will inform on optimizing vaccine delivery.Archived pl
Externí odkaz:
https://doaj.org/article/3bce2188aa5a410b925d01d1299ade4c
Autor:
Bailey B. Banach, Prabhanshu Tripathi, Lais Da Silva Pereira, Jason Gorman, Thuy Duong Nguyen, Marlon Dillon, Ahmed S. Fahad, Patience K. Kiyuka, Bharat Madan, Jacy R. Wolfe, Brian Bonilla, Barbara Flynn, Joseph R. Francica, Nicholas K. Hurlburt, Neville K. Kisalu, Tracy Liu, Li Ou, Reda Rawi, Arne Schön, Chen-Hsiang Shen, I-Ting Teng, Baoshan Zhang, Marie Pancera, Azza H. Idris, Robert A. Seder, Peter D. Kwong, Brandon J. DeKosky
Publikováno v:
Journal of Experimental Medicine. 219
The monoclonal antibody CIS43 targets the Plasmodium falciparum circumsporozoite protein (PfCSP) and prevents malaria infection in humans for up to 9 mo following a single intravenous administration. To enhance the potency and clinical utility of CIS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07bc2911602baf5e3f279ab12090b23
https://doi.org/10.1084/jem.20220323
https://doi.org/10.1084/jem.20220323
Publikováno v:
Febs Letters
The malaria parasite has for long been thought to escape host complement attack as a survival strategy. However, it was only recently that complement evasion mechanisms of the parasite were described. Simultaneously, the role of complement in antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9c845ce5eb99ed25aba63c515d8894
https://doi.org/10.1002/1873-3468.13772
https://doi.org/10.1002/1873-3468.13772
Autor:
Lawrence T. Wang, Nicholas K. Hurlburt, Arne Schön, Barbara J. Flynn, Yevel Flores-Garcia, Lais S. Pereira, Patience K. Kiyuka, Marlon Dillon, Brian Bonilla, Fidel Zavala, Azza H. Idris, Joseph R. Francica, Marie Pancera, Robert A. Seder
Publikováno v:
Cell Rep
L9 is a potent human monoclonal antibody (mAb) that preferentially binds two adjacent NVDP minor repeats and cross-reacts with NANP major repeats of the Plasmodium falciparum circumsporozoite protein (PfCSP) on malaria-infective sporozoites. Understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2c290c68fa486b9a7763d010bf7d9b
https://pubmed.ncbi.nlm.nih.gov/35172158
https://pubmed.ncbi.nlm.nih.gov/35172158
Autor:
Joseph R. Francica, Eleonora Melzi, Baoshan Zhang, Kai Xu, Ying-Cing Lin, Kareen Seignon, Tracy Liu, Chen-Hsiang Shen, Gwo-Yu Chuang, John Warner, Marie Pancera, Usha Nair, Arne Schön, Lais Pereira, Prabhanshu Tripathi, Michael T. Waring, Peter D. Kwong, Sven Kratochvil, Reda Rawi, Lawrence T. Wang, Marlon Dillon, Li Ou, Yongping Yang, Barbara J. Flynn, Azza H. Idris, Robert A. Seder, Kathrin H Kirsch, Neville K. Kisalu, Brian Bonilla, Patience K. Kiyuka, Mateo Reveiz, Facundo D. Batista, Johan Arnold
Publikováno v:
Immunity
Repeat antigens, such as the Plasmodium falciparum circumsporozoite protein (PfCSP), use both sequence degeneracy and structural diversity to evade the immune response. A few PfCSP-directed antibodies have been identified that are effective at preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723d9566afd2ea78b157b9210ea7e7a3
https://pubmed.ncbi.nlm.nih.gov/34910937
https://pubmed.ncbi.nlm.nih.gov/34910937
Autor:
Charles N. Agoti, Grieven P. Otieno, Patrick K. Munywoki, Anne Bett, Matthew Cotten, D. James Nokes, Patience K. Kiyuka, Regina Njeru, Taane G. Clark, Paul Kellam, László van den Hoek, Everlyn Kamau, James R. Otieno
Publikováno v:
Journal of infectious diseases, 217(11), 1728-1739. Oxford University Press
The Journal of Infectious Diseases
Journal of Infectious Diseases, 217(11), 1728-1739. Oxford University Press
The Journal of Infectious Diseases
Journal of Infectious Diseases, 217(11), 1728-1739. Oxford University Press
Background Human coronavirus NL63 (HCoV-NL63) is a globally endemic pathogen causing mild and severe respiratory tract infections with reinfections occurring repeatedly throughout a lifetime. Methods Nasal samples were collected in coastal Kenya thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8cabd4d9d086afd5ad8b075ba049aa
https://doi.org/10.1093/infdis/jiy098
https://doi.org/10.1093/infdis/jiy098
Autor:
Horace Gumba, Perpetual Wanjiku, S J Mwangi, Clement Lewa, Agnes Mutiso, O Kai, W Gumbi, S Njuguna, John N. Gitonga, Donwilliams O. Omuoyo, Patience K. Kiyuka, Charles N. Agoti, D Riako, F Mitsanze, Salim Mwarumba, Amek Nyaguara, K Said Mohammed, Y Sein, Domtila Kimani, Z R de Laurent, Daisy Mugo, Edward Otieno, Lydia Nyamako, Lynette Isabella Ochola-Oyier, Jennifer N. Musyoki, B M Gichuki, Victor Osoti, A Mwakubia, B Tawa, A Mwanzu, Elijah Gicheru, M Rono, W Cheruiyot, Angela Karani, Metrine Tendwa, K Ominde, Johnstone Makale, Caroline Ngetsa, Boniface Karia, John M. Morobe, M Opiyo, M Mosobo, David Amadi, Martin Mutunga, W Nyamu, Benjamin Tsofa, N Ouma, Philip Bejon, Arnold W. Lambisia, Jedidah Mwacharo, Shadrack Mutua, Robinson Cheruiyot, Calleb Odundo, B Bartilol, J Thoya
Publikováno v:
Wellcome Open Research. 6:205
Laboratory diagnosis plays a critical role in the containment of a pandemic. Strong laboratory quality management systems (QMS) are essential for laboratory diagnostic services. However, low laboratory capacities in resource-limited countries has mad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bf71fd25fc824ef0aff5287bfd2570
https://doi.org/10.12688/wellcomeopenres.16704.1
https://doi.org/10.12688/wellcomeopenres.16704.1
Autor:
J. Anthony G. Scott, D. James Nokes, Joyce U. Nyiro, Patrick K. Munywoki, Patience K. Kiyuka, Charles J. Sande, Martin Mutunga
Publikováno v:
Wellcome Open Research
Background: Severe disease associated with respiratory syncytial virus (RSV) infection occurs predominantly among infants under 6 months of age. Vaccines for prevention are in clinical development. Assessment of the vaccine effectiveness in large epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec83af0a0efc59700e1d5ae08a6cb6c8
https://doi.org/10.12688/wellcomeopenres.15108.1
https://doi.org/10.12688/wellcomeopenres.15108.1
