Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Patience, Eschenhagen"'
Autor:
Jochen G. Mainz, Anton Barucha, Pu Huang, Lilith Bechinger, Franziska Duckstein, Louise Polte, Pauline Sadrieh, Lutz Nährlich, Olaf Eickmeier, Suzanne Van Dullemen, Patience Eschenhagen, Carsten Schwarz, Stefan Lüth, Carlos Zagoya, Ute Graepler-Mainka
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Elexacaftor–tezacaftor–ivacaftor (ETI) is a novel, highly effective CFTR modulator combination proven to enhance lung function and body weight in people with cystic fibrosis (pwCF) carrying a F508del mutation. Recently, we revealed si
Externí odkaz:
https://doaj.org/article/658abcaaf09940f9aee5d184e373a9e4
Autor:
Jochen G. Mainz, Carlos Zagoya, Louise Polte, Lutz Naehrlich, Lenny Sasse, Olaf Eickmeier, Christina Smaczny, Anton Barucha, Lilith Bechinger, Franziska Duckstein, Ludwik Kurzidim, Patience Eschenhagen, Laura Caley, Daniel Peckham, Carsten Schwarz
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/fdf445ccbf604305b8dbc4b1e0461e15
Autor:
Carsten Schwarz, Patience Eschenhagen, Henrijette Schmidt, Thordis Hohnstein, Christina Iwert, Claudia Grehn, Jobst Roehmel, Eva Steinke, Mirjam Stahl, Laura Lozza, Ekaterina Tikhonova, Elisa Rosati, Ulrik Stervbo, Nina Babel, Jochen G. Mainz, Hilmar Wisplinghoff, Frank Ebel, Lei-Jie Jia, Matthew G. Blango, Peter Hortschansky, Sascha Brunke, Bernhard Hube, Axel A. Brakhage, Olaf Kniemeyer, Alexander Scheffold, Petra Bacher
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
BACKGROUND The fungus Aspergillus fumigatus causes a variety of clinical phenotypes in patients with cystic fibrosis (pwCF). Th cells orchestrate immune responses against fungi, but the types of A. fumigatus–specific Th cells in pwCF and their cont
Externí odkaz:
https://doaj.org/article/952a35bb46204b4d99016140937e7c30
Autor:
Astrid Lewin, Elisabeth Kamal, Torsten Semmler, Katja Winter, Sandra Kaiser, Hubert Schäfer, Lei Mao, Patience Eschenhagen, Claudia Grehn, Jennifer Bender, Carsten Schwarz
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2415-2429 (2021)
Mycobacterium (M.) abscessus infections in Cystic Fibrosis (CF) patients cause a deterioration of lung function. Treatment of these multidrug-resistant pathogens is associated with severe side-effects, while frequently unsuccessful. Insight on M. abs
Externí odkaz:
https://doaj.org/article/0f2081c8922a48828890383cafb62789
Autor:
Jochen G. Mainz, Carlos Zagoya, Louise Polte, Lutz Naehrlich, Lenny Sasse, Olaf Eickmeier, Christina Smaczny, Anton Barucha, Lilith Bechinger, Franziska Duckstein, Ludwik Kurzidim, Patience Eschenhagen, Laura Caley, Daniel Peckham, Carsten Schwarz
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: The novel and highly effective CFTR modulator combination of elexacaftor-tezacaftor-ivacaftor (ETI) has been shown to improve lung function and body weight in people with Cystic Fibrosis (pwCF) carrying a F508del mutation. However, the im
Externí odkaz:
https://doaj.org/article/463ecbf462624e5c9175afeacb5af8f4
Autor:
Claudia Grehn, Patience Eschenhagen, Svenja Temming, Uta Düesberg, Konrad Neumann, Carsten Schwarz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Aspergillus fumigatus (Af) frequently colonizes the respiratory tract of patients with cystic fibrosis (CF). Af is associated with loss of pulmonary function and allergic bronchopulmonary aspergillosis (ABPA), a hypersensitivity fungal lung disease.
Externí odkaz:
https://doaj.org/article/f3c3a821634b4199ba4752fe05912d13
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
BackgroundIn Cystic Fibrosis (CF), the airways are often colonized by opportunistic fungi. The most frequently detected mold is Aspergillus fumigatus (Af). Af diseases are associated with significant morbidity and mortality. The most common clinical
Externí odkaz:
https://doaj.org/article/386237c29caf445d9ca851590520dd44
Autor:
Claudia Grehn, Patience Eschenhagen, Svenja Temming, Uta Düesberg, Konrad Neumann, Carsten Schwarz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Aspergillus fumigatus (Af) frequently colonizes the airways of patients with cystic fibrosis (CF) and can cause severe diseases, such as allergic bronchopulmonary aspergillosis, Af bronchitis or even Af pneumonia. However, risk factors, including env
Externí odkaz:
https://doaj.org/article/a88a3d09895246f0923573b4fd8cd692
Autor:
Iris Stoler, Judith Freytag, Banu Orak, Nadine Unterwalder, Stephan Henning, Katrin Heim, Horst von Bernuth, Renate Krüger, Stefan Winkler, Patience Eschenhagen, Eva Seipelt, Marcus A. Mall, Dirk Foell, Christoph Kessel, Helmut Wittkowski, Tilmann Kallinich
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Familial Mediterranean fever (FMF) is caused by mutations within the Mediterranean fever (MEFV) gene. Disease severity depends on genotype and gene dose with most serious clinical courses observed in patients with M694V homozygosity. Neutrophils are
Externí odkaz:
https://doaj.org/article/a1c3e7814b824bd68df15cea7d1550ad
Autor:
Richard B. Moss, Gina Hong, Carsten Schwarz, Sameer Desai, Bradley S. Quon, Patience Eschenhagen
Publikováno v:
J Cyst Fibros
Background The diagnosis and treatment of Aspergillus fumigatus (Af)-related conditions remain a challenge in cystic fibrosis (CF) due to overlapping features of disease and absence of clinical guidelines for Af-related conditions outside of ABPA. Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c24bde15795ea5fb0aecff9390584b
https://doi.org/10.1016/j.jcf.2021.07.008
https://doi.org/10.1016/j.jcf.2021.07.008