Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Pathmanathan, Rajadurai"'
Autor:
Jia-Wern Pan, Zi-Ching Tan, Pei-Sze Ng, Muhammad Mamduh Ahmad Zabidi, Putri Nur Fatin, Jie-Ying Teo, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Triple-negative breast cancers (TNBCs) are a subset of breast cancers that have remained difficult to treat. A proportion of TNBCs arising in non-carriers of BRCA pathogenic variants have genomic features that are similar to BRCA carriers an
Externí odkaz:
https://doaj.org/article/d2857e682b734986b417f18c09ab31e4
Autor:
Jia-Wern Pan, Mohana Ragu, Wei-Qin Chan, Siti Norhidayu Hasan, Tania Islam, Li-Ying Teoh, Suniza Jamaris, Mee-Hoong See, Cheng-Har Yip, Pathmanathan Rajadurai, Lai-Meng Looi, Nur Aishah Mohd Taib, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Joanna Lim, Soo-Hwang Teo
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to investigate the existence of distinct subtypes of breast cancer within the Asian populati
Externí odkaz:
https://doaj.org/article/351360a830af473c9b955d098b6ff1fa
Autor:
Mohana Eswari Ragu, Joanna Mei Ch’wan Lim, Pei-Sze Ng, Cheng-Har Yip, Pathmanathan Rajadurai, Soo-Hwang Teo, Jia-Wern Pan
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Recent genomics studies of breast cancer in Asian cohorts have found a higher prevalence of TP53 mutations in Asian breast cancer patients relative to Caucasian patients. However, the effect of TP53 mutations on Asian breast tumou
Externí odkaz:
https://doaj.org/article/e2a9a5d4c3e54315b9693ca107bf1b7e
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 1, Pp 31-43 (2023)
Lung cancer is one of the most common cancers and a leading cause of cancer-related mortality in Malaysia. This analysis aimed to evaluate the prevalence of actionable and common mutations, as well as co-mutations frequently occurring with EGFR varia
Externí odkaz:
https://doaj.org/article/f0d2746ca22e4b5185a60402f8f01d92
Autor:
Ken Lee Wan, Arkendu Sen, Lakshmi Selvaratnam, Mohd Imran Mohd Naing, Joon Joon Khoo, Pathmanathan Rajadurai
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Literature review demonstrated a surprising lack of publications on digital e-learning pathology resources for senior medical undergraduates and interns. An interactive Digital Pathology Repository (iDPR) integrating two- and three-dimension
Externí odkaz:
https://doaj.org/article/89484c42bae644a0a380c1fda8c86d68
Autor:
Pei Sze Ng, Jia Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pathmanathan Rajadurai, Cheng Har Yip, Oscar M. Reuda, Alison M. Dunning, Antonis C. Antoniou, Douglas F. Easton, Carlos Caldas, Suet-Feung Chin, Soo Hwang Teo
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Rare protein-truncating variants (PTVs) in PALB2 confer increased risk to breast cancer, but relatively few studies have reported the characteristics of tumours with PALB2 PTVs. In this study, we describe molecular characteristics of tumours
Externí odkaz:
https://doaj.org/article/0aad972192044d50993ee44394768c43
Autor:
Jia-Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pei-Sze Ng, Mei-Yee Meng, Siti Norhidayu Hasan, Bethan Sandey, Stephen-John Sammut, Cheng-Har Yip, Pathmanathan Rajadurai, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Soo-Hwang Teo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Molecular profiling of breast cancer in non-Caucasian populations remains underexplored. Here the authors report a high prevalence of HER2-subtypes and enriched immune score with improved survival and higher rates of TP53 somatic mutations with poore
Externí odkaz:
https://doaj.org/article/19a345c9f0be4ab783dcad50c106ed15
Autor:
Jew Win Kuan, Sing Ling Chai, Pathmanathan Rajadurai, Lee Gong Lau, Joseph Uchang, Sharifah Noor Akmal Syed Husain
Publikováno v:
Case Reports in Hematology, Vol 2022 (2022)
Central nervous system (CNS) involvement in multiple myeloma (MM) (MM-CNS) in the form of leptomeningeal myelomatosis or brain parenchyma plasmacytoma is rare, causing challenges in clinical diagnosis and treatment. We would like to report a case of
Externí odkaz:
https://doaj.org/article/234562dfe5c9459d9d7f3e76df51909a
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Curcumin analogs with excellent biological properties have been synthesized to address and overcome the poor pharmacokinetic profiles of curcumin. This study aims to investigate the cytotoxicity, anti-proliferative, and apoptosis-inducing ability of
Externí odkaz:
https://doaj.org/article/bb6b6e44d46049189abeb392ec33bad8
Autor:
Jayalakshmi Pailoor, Venupriya Ramasamy, Yousoof Saira Bahnu, Cheng-Eng Koay, Kian-Meng Chang, Pathmanathan Rajadurai
Publikováno v:
Respiratory Medicine Case Reports, Vol 31, Iss , Pp 101218- (2020)
Externí odkaz:
https://doaj.org/article/38648ae407dc47b192a9ca16d214e6e1