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Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci

Autor: Devries, Amber A, Dennis, Joe, Tyrer, Jonathan P, Peng, Pei-chen, Coetzee, Simon G, Reyes, Alberto L, Plummer, Jasmine T, Davis, Brian D, Chen, Stephanie S, Dezem, Felipe Segato, Aben, Katja K H, Anton-culver, Hoda, Antonenkova, Natalia N, Beckmann, Matthias W, Beeghly-fadiel, Alicia, Berchuck, Andrew, Bogdanova, Natalia V, Bogdanova-markov, Nadja, Brenton, James D, Butzow, Ralf, Campbell, Ian, Chang-claude, Jenny, Chenevix-trench, G, Cook, Linda S, Defazio, A, Doherty, Jennifer A, Dörk, Thilo, Eccles, Diana M, Eliassen, A Heather, Fasching, Peter A, Fortner, Renée T, Giles, Graham G, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Webb, P, Friedlander, M, Obermair, A, Grant, P, Nagle, C, Beesley, V, Chevenix-trench, G, Bowtell, D, Blomfield, P, Brand, A, Davis, A, Leung, Y, Nicklin, J, Quinn, M, Livingstone, K, O'neill, H, Williams, M, Black, A, Hadley, A, Glasgow, A, Garrett, A, Rao, A, Shannon, C, Steer, C, Allen, D, Neesham, D, Otton, G, Au-yeung, G, Goss, G, Wain, G, Gard, G, Robertson, G, Lombard, J, Tan, J, Mcneilage, J, Power, J, Coward, J, Miller, J, Carter, J, Lamont, J, Wong, K M, Reid, K, Perrin, L, Milishkin, L, Nascimento, M, Buck, M, Bunting, M, Harrison, M, Chetty, N, Hacker, N, Mcnally, O, Harnett, P, Beale, P, Awad, R, Mohan, R, Farrell, R, Mcintosh, R, Rome, R, Sayer, R, Houghton, R, Hogg, R, Land, R, Baron-hay, S, Paramasivum, S, Pather, S, Hyde, S, Salfinger, S, Valmadre, S, Jobling, T, Manolitsas, T, Bonaventura, T, Arora, V, Green, A, Gertig, D, Traficante, N, Fereday, S, Moore, S, Hung, J, Harrap, K, Sadkowsky, T, Pandeya, N, Malt, M, Robertson, R, Bergh, T Vanden, Jones, M, Mckenzie, P, Maidens, J, Nattress, K, Chiew, Y E, Stenlake, A, Sullivan, H, Alexander, B, Ashover, P, Brown, S, Corrish, T, Green, L, Jackman, L, Ferguson, K, Martin, K, Martyn, A, Ranieri, B, White, J, Jayde, V, Bowes, L, Mamers, P, Galletta, L, Giles, D, Hendley, J, Alsop, K, Schmidt, T, Shirley, H, Ball, C, Young, C, Viduka, S, Tran, H, Bilic, S, Glavinas, L, Brooks, J, Stuart-harris, R, Kirsten, F, Rutovitz, J, Clingan, P, Proietto, A, Braye, S, Shannon, J, Stewart, J, Begbie, S, Håkansson, Niclas, Hildebrandt, Michelle A T, Huff, Chad, Huntsman, David G, Jensen, Allan, Kar, Siddhartha, Karlan, Beth Y, Khusnutdinova, Elza K, Kiemeney, Lambertus A, Kjaer, Susanne K, Kupryjanczyk, Jolanta, Labrie, Marilyne, Lambrechts, Diether, Le, Nhu D, Lubiński, Jan, May, Taymaa, Menon, Usha, Milne, Roger L, Modugno, Francesmary, Monteiro, Alvaro N, Moysich, Kirsten B, Odunsi, Kunle, Olsson, Håkan, Pearce, Celeste L, Pejovic, Tanja, Ramus, Susan J, Riboli, Elio, Riggan, Marjorie J, Romieu, Isabelle, Sandler, Dale P, Schildkraut, Joellen M, Setiawan, V Wendy, Sieh, Weiva, Song, Honglin, Sutphen, Rebecca, Terry, Kathryn L, Thompson, Pamela J, Titus, Linda, Tworoger, Shelley S, Van Nieuwenhuysen, Els, Edwards, Digna Velez, Webb, Penelope M, Wentzensen, Nicolas, Whittemore, Alice S, Wolk, Alicja, Wu, Anna H, Ziogas, Argyrios, Freedman, Matthew L, Lawrenson, Kate, Pharoah, Paul D P, Easton, Douglas F, Gayther, Simon A, Jones, Michelle R

Publikováno v: Journal of the National Cancer Institute, 114, 1533-1544
Journal of the National Cancer Institute, 114, 11, pp. 1533-1544
Devries, A A, Dennis, J, Tyrer, J P, Peng, P, Coetzee, S G, Reyes, A L, Plummer, J T, Davis, B D, Chen, S S, Dezem, F S, Aben, K K H, Anton-culver, H, Antonenkova, N N, Beckmann, M W, Beeghly-fadiel, A, Berchuck, A, Bogdanova, N V, Bogdanova-markov, N, Brenton, J D, Butzow, R, Campbell, I, Chang-claude, J, Chenevix-trench, G, Cook, L S, Defazio, A, Doherty, J A, Dörk, T, Eccles, D M, Eliassen, A H, Fasching, P A, Fortner, R T, Giles, G G, Goode, E L, Goodman, M T, Gronwald, J, Webb, P, Defazio, A, Friedlander, M, Obermair, A, Grant, P, Nagle, C, Beesley, V, Chevenix-trench, G, Bowtell, D, Blomfield, P, Brand, A, Davis, A, Leung, Y, Nicklin, J, Quinn, M, Livingstone, K, O'neill, H, Williams, M, Black, A, Hadley, A, Glasgow, A, Garrett, A, Rao, A, Shannon, C, Steer, C, Allen, D, Neesham, D, Otton, G, Au-yeung, G, Goss, G, Wain, G, Gard, G, Robertson, G, Lombard, J, Tan, J, Mcneilage, J, Power, J, Coward, J, Miller, J, Carter, J, Lamont, J, Wong, K M, Reid, K, Perrin, L, Milishkin, L, Nascimento, M, Buck, M, Bunting, M, Harrison, M, Chetty, N, Hacker, N, Mcnally, O, Harnett, P, Beale, P, Awad, R, Mohan, R, Farrell, R, Mcintosh, R, Rome, R, Sayer, R, Houghton, R, Hogg, R, Land, R, Baron-hay, S, Paramasivum, S, Pather, S, Hyde, S, Salfinger, S, Valmadre, S, Jobling, T, Manolitsas, T, Bonaventura, T, Arora, V, Bowtell, D, Chenevix-trench, G, Green, A, Webb, P, Defazio, A, Gertig, D, Traficante, N, Fereday, S, Moore, S, Hung, J, Harrap, K, Sadkowsky, T, Pandeya, N, Malt, M, Robertson, R, Bergh, T V, Jones, M, Mckenzie, P, Maidens, J, Nattress, K, Chiew, Y E, Stenlake, A, Sullivan, H, Alexander, B, Ashover, P, Brown, S, Corrish, T, Green, L, Jackman, L, Ferguson, K, Martin, K, Martyn, A, Ranieri, B, White, J, Jayde, V, Bowes, L, Mamers, P, Galletta, L, Giles, D, Hendley, J, Alsop, K, Schmidt, T, Shirley, H, Ball, C, Young, C, Viduka, S, Tran, H, Bilic, S, Glavinas, L, Brooks, J, Stuart-harris, R, Kirsten, F, Rutovitz, J, Clingan, P, Glasgow, A, Proietto, A, Braye, S, Otton, G, Shannon, J, Bonaventura, T, Stewart, J, Begbie, S, Håkansson, N, Hildebrandt, M A T, Huff, C, Huntsman, D G, Jensen, A, Kar, S, Karlan, B Y, Khusnutdinova, E K, Kiemeney, L A, Kjaer, S K, Kupryjanczyk, J, Labrie, M, Lambrechts, D, Le, N D, Lubiński, J, May, T, Menon, U, Milne, R L, Modugno, F, Monteiro, A N, Moysich, K B, Odunsi, K, Olsson, H, Pearce, C L, Pejovic, T, Ramus, S J, Riboli, E, Riggan, M J, Romieu, I, Sandler, D P, Schildkraut, J M, Setiawan, V W, Sieh, W, Song, H, Sutphen, R, Terry, K L, Thompson, P J, Titus, L, Tworoger, S S, Van Nieuwenhuysen, E, Edwards, D V, Webb, P M, Wentzensen, N, Whittemore, A S, Wolk, A, Wu, A H, Ziogas, A, Freedman, M L, Lawrenson, K, Pharoah, P D P, Easton, D F, Gayther, S A & Jones, M R 2022, ' Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci ', Journal of the National Cancer Institute, vol. 114, no. 11, djac160, pp. 1533–1544 . https://doi.org/10.1093/jnci/djac160
DeVries, A A, Dennis, J, Tyrer, J P, Peng, P-C, Coetzee, S G, Reyes, A L, Plummer, J T, Davis, B D, Chen, S S, Dezem, F S, Aben, K K H, Anton-Culver, H, Antonenkova, N N, Beckmann, M W, Beeghly-Fadiel, A, Berchuck, A, Bogdanova, N, Bogdanova-Markov, N, Brenton, J D, Butzow, R, Campbell, I, Chang-Claude, J, Chenevix-Trench, G, Cook, L S, DeFazio, A, Doherty, J A, Dork, T, Eccles, D M, Eliassen, A H, Fasching, P A, Fortner, R T, Giles, G G, Goode, E L, Goodman, M T, Gronwald, J, Hakansson, N, Hildebrandt, M A T, Huff, C, Huntsman, D G, Jensen, A, Kar, S, Karlan, B Y, Khusnutdinova, E K, Kiemeney, L A, Kjaer, S K, Kupryjanczyk, J, Labrie, M, Lambrechts, D, Le, N D, Lubinski, J, OPAL Study Grp & AOCS Grp 2022, ' Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci ', Journal of the National Cancer Institute, vol. 114, no. 11, pp. 1533–1544 . https://doi.org/10.1093/jnci/djac160

Background Known risk alleles for epithelial ovarian cancer (EOC) account for approximately 40% of the heritability for EOC. Copy number variants (CNVs) have not been investigated as EOC risk alleles in a large population cohort. Methods Single nucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cf085490059f457d7c042d0a46fcbf
http://hdl.handle.net/10138/353572

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