Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patel Mahest"'
Publikováno v:
Journal of Pharmaceutical Sciences. 88:454-458
Intravenous lipid emulsions are used for total parenteral nutrition and as carriers for lipophilic drugs. Exposure to the high temperature (121 degrees C) required for steam sterilization may cause coalescence and an increase in droplet size. The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ccc0c63d6b8d27b66d2b7613a8b38c
https://doi.org/10.1021/js980293i
https://doi.org/10.1021/js980293i
Autor:
Ping Gao, K.C. Sung, Patel Mahest, T. Robert Ju, John W. Skoug, Phillip R. Nixon, Elizabeth M. Topp
Publikováno v:
International Journal of Pharmaceutics. 142:53-60
The objective of this work was to assess the effect of two formulation variables, hydroxypropylmethylcellulose (HPMC)/lactose ratio and HPMC viscosity grade, on the release of a model drug and HPMC, as well as the mechanism of drug release from HPMC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4386cfb97f9291fb3eaaabb8e7abe9ce
https://doi.org/10.1016/0378-5173(96)04644-3
https://doi.org/10.1016/0378-5173(96)04644-3
Publikováno v:
Journal of Pharmaceutical Sciences. 84:1455-1463
Two scaling laws for predicting polymer and drug release profiles from hydrophilic matrices were developed. They were developed on the basis of the diffusion layer and the polymer disentanglement concentration, rho p,dis, the critical polymer concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c16b1156ccf8cf7fbced5d0d3e7b60
https://doi.org/10.1002/jps.2600841213
https://doi.org/10.1002/jps.2600841213
Publikováno v:
Journal of pharmaceutical sciences. 86(11)
A semiempirical formula was developed for the diffusion coefficient, Dp, of polymer within the diffusion layer adjacent to a matrix undergoing swelling and dissolution. This formula of Dp was a key element in a comprehensive mathematical model that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855f8dd719a3295ded85f3b0233d6e39
https://pubmed.ncbi.nlm.nih.gov/9383743
https://pubmed.ncbi.nlm.nih.gov/9383743
Publikováno v:
Journal of pharmaceutical sciences. 84(12)
A comprehensive model is developed to describe the swelling/dissolution behaviors and drug release from hydrophilic matrices. The major thrust of this model is to employ an important physical property of the polymer, the polymer disentanglement conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2616f5eaac07b866bc9297bc15f4a4fc
https://pubmed.ncbi.nlm.nih.gov/8748330
https://pubmed.ncbi.nlm.nih.gov/8748330