Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection

Autor: Peiró, T, Patel, DF, Akthar, S, Gregory, LG, Pyle, CJ, Harker, JA, Birrell, MA, LLoyd, CM, Snelgrove, RJ

Background Alveolar macrophages are sentinels of the airways that must exhibit immune restraint to innocuous antigens but elicit a robust inflammatory response to pathogenic threats. How distinction between these dichotomous functions is controlled i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::38fa67834cb846c8ffdde0eaa282e551
http://hdl.handle.net/10044/1/51722

Discovery of Red-Shifting Mutations in Firefly Luciferase Using High-Throughput Biochemistry.

Autor: Colee CM; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Oberlag NM; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Simon M; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Chapman OS; Department of Biology, Pomona College, Claremont, California 91711, United States., Flanagan LC; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Reid-McLaughlin ES; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Gewing-Mullins JA; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Maiche S; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Patel DF; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States., Cavalcanti ARO; Department of Biology, Pomona College, Claremont, California 91711, United States., Leconte AM; W.M. Keck Science Department of Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, California 91711, United States.

Publikováno v: Biochemistry [Biochemistry] 2024 Mar 19; Vol. 63 (6), pp. 733-742. Date of Electronic Publication: 2024 Mar 04.

Differential Regulation of Allergic Airway Inflammation by Acetylcholine.

Autor: Roberts LB; Department of Life Sciences, Imperial College London, London, United Kingdom.; School of Immunology and Microbial Sciences, King's College London, Great Maze Pond, London, United Kingdom., Berkachy R; Department of Life Sciences, Imperial College London, London, United Kingdom., Wane M; Department of Life Sciences, Imperial College London, London, United Kingdom., Patel DF; National Heart and Lung Institute, Imperial College London, London, United Kingdom., Schnoeller C; Department of Life Sciences, Imperial College London, London, United Kingdom., Lord GM; School of Immunology and Microbial Sciences, King's College London, Great Maze Pond, London, United Kingdom.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Gounaris K; Department of Life Sciences, Imperial College London, London, United Kingdom., Ryffel B; Laboratory of Molecular and Experimental Immunology and Neurogenetics, UMR 7355, CNRS-University of Orleans and Le Studium Institute for Advanced Studies, Rue Dupanloup, Orléans, France., Quesniaux V; Laboratory of Molecular and Experimental Immunology and Neurogenetics, UMR 7355, CNRS-University of Orleans and Le Studium Institute for Advanced Studies, Rue Dupanloup, Orléans, France., Darby M; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Horsnell WGC; Laboratory of Molecular and Experimental Immunology and Neurogenetics, UMR 7355, CNRS-University of Orleans and Le Studium Institute for Advanced Studies, Rue Dupanloup, Orléans, France.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Selkirk ME; Department of Life Sciences, Imperial College London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 May 27; Vol. 13, pp. 893844. Date of Electronic Publication: 2022 May 27 (Print Publication: 2022).

Abnormal pro-gly-pro pathway and airway neutrophilia in pediatric cystic fibrosis.

Autor: Turnbull AR; Cystic Fibrosis and Chronic Lung Infection, National Heart & Lung Institute, Imperial College London, United Kingdom; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom., Pyle CJ; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Patel DF; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Jackson PL; Division of Pulmonary, Allergy and Critical Care Medicine, Program in Protease and Matrix Biology, Gregory Fleming James Cystic Fibrosis Centre and Lung Health Center, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America; Birmingham V.A. Medical Centre, Birmingham, AL 35294, United States of America., Hilliard TN; Cystic Fibrosis and Chronic Lung Infection, National Heart & Lung Institute, Imperial College London, United Kingdom; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom., Regamey N; Paediatric Respiratory Medicine, Children's Hospital, Lucerne, Switzerland., Tan HL; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom., Brown S; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Thursfield R; Alder Hey Children's NHS Foundation Trust, Liverpool L14 5AB, United Kingdom., Short C; Cystic Fibrosis and Chronic Lung Infection, National Heart & Lung Institute, Imperial College London, United Kingdom., Mc Fie M; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Alton EWFW; Cystic Fibrosis and Chronic Lung Infection, National Heart & Lung Institute, Imperial College London, United Kingdom., Gaggar A; Division of Pulmonary, Allergy and Critical Care Medicine, Program in Protease and Matrix Biology, Gregory Fleming James Cystic Fibrosis Centre and Lung Health Center, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America; Birmingham V.A. Medical Centre, Birmingham, AL 35294, United States of America., Blalock JE; Division of Pulmonary, Allergy and Critical Care Medicine, Program in Protease and Matrix Biology, Gregory Fleming James Cystic Fibrosis Centre and Lung Health Center, University of Alabama at Birmingham, Birmingham, AL 35294, United States of America., Lloyd CM; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Bush A; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom., Davies JC; Cystic Fibrosis and Chronic Lung Infection, National Heart & Lung Institute, Imperial College London, United Kingdom; Paediatric Respiratory Medicine, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom., Snelgrove RJ; Inflammation Repair and Development, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom. Electronic address: robert.snelgrove@imperial.ac.uk.

Publikováno v: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2020 Jan; Vol. 19 (1), pp. 40-48. Date of Electronic Publication: 2019 Jun 05.

Zooming into the Matrix: Using Nonlinear Optical Microscopy to Visualize Collagen Remodeling in Asthmatic Airways.

Autor: Snelgrove RJ; 1National Heart and Lung InstituteImperial College LondonLondon, United Kingdom., Patel DF; 1National Heart and Lung InstituteImperial College LondonLondon, United Kingdom.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2019 Aug 15; Vol. 200 (4), pp. 403-405.