Evolutionary targeted discovery of influenza A virus replication inhibitors

Autor: Patel, Hershna

Influenza A is one of the most prevalent and significant viral infections worldwide, resulting in annual epidemics and occasional pandemics. Upon infection, antiviral drugs targeting the neuraminidase protein and M2 protein are the only treatment opt

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732870

Integrating molecular modelling methods to advance influenza A virus drug discovery

Autor: Patel, Hershna, Kukol, Andreas

Publikováno v: In Drug Discovery Today February 2021 26(2):503-510

C2 by-pass: Cross-talk between the complement classical and alternative pathways

Autor: Laich, Andy, Patel, Hershna, Zarantonello, A., Sim, R. B., Inal, Jameel

Publikováno v: Laich, A, Patel, H, Zarantonello, A, Sim, R B & Inal, J M 2022, ' C2 by-pass : Cross-talk between the complement classical and alternative pathways ', Immunobiology, vol. 227, no. 3, 152225 . https://doi.org/10.1016/j.imbio.2022.152225

Several disorders associated with the total or partial absence of components of the human complement system are known. Deficiencies of classical pathway (CP) components are generally linked to systemic lupus erythematosus (SLE) or SLE-like syndromes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404032655d6071f81de50a29ffc580c8
https://pubmed.ncbi.nlm.nih.gov/35567980

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