Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pat LoRusso"'
Autor:
Susan Dent, Anthony Gonçalves, Joo-Hee Yi, Alexander Strasak, Pat LoRusso, Sandhya Girish, Priya Agarwal, Chunze Li, Marjorie C. Green
Publikováno v:
Cancer Research. 75:P4-15
Introduction Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate comprising trastuzumab, a stable linker, and the microtubule inhibitor DM1. In phase 3 studies of HER2-positive metastatic breast cancer (MBC), T-DM1 significantly increased p
Publikováno v:
Cancer chemotherapy and biological response modifiers. 22
Autor:
Evelyn Jiagge, Max S. Wicha, Pat LoRusso, John D. Carpten, Ahmet Kurdoglu, Lisa A. Newman, David Craig, Sean P. McDermott, Sofia D. Merajver, Shukmei Wong, Jeffery M. Trent, Shawn G. Clouthier, Tahra Luthur, Jessica Aldrich
Publikováno v:
Cancer Research. 74:LB-59
Background: Triple negative breast cancer (TNBC) carry poor prognosis in all ethnicities, and patients of African ancestry have a higher incidence of TNBC. We hypothesize that there are distinct signaling pathways active in the mesenchymal (CD44+CD24