Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pat, Dorr"'
Autor:
Charles A, Boucher, Marina R, Bobkova, Chien-Ching, Hung, Rolf, Kaiser, Anne-Geneviève, Marcelin, Adrian, Streinu-Cercel, Jean, van Wyk, Pat, Dorr, Anne-Mieke, Vandamme
Publikováno v:
AIDS reviews. 20(1)
This article is the second of a two-part review aiming to identify gaps in the knowledge and management of human immunodeficiency virus type 1 drug resistance (HIVDR) from global and regional perspectives. Here, we examine the policy and programmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91ba6e75ce90c9e0b503b3e8d0568ec9
https://pubmed.ncbi.nlm.nih.gov/29628514
https://pubmed.ncbi.nlm.nih.gov/29628514
Autor:
Charles A, Boucher, Marina R, Bobkova, Anna Maria, Geretti, Chien-Ching, Hung, Rolf, Kaiser, Anne-Geneviève, Marcelin, Adrian, Streinu-Cercel, Jean, van Wyk, Pat, Dorr, Anne-Mieke, Vandamme
Publikováno v:
AIDS reviews. 20(1)
Resistance to antiretroviral therapy (ART) threatens the efficacy of human immunodeficiency virus type 1 (HIV-1) treatment. We present a review of knowledge gaps in the science and technologies of acquired HIV-1 drug resistance (HIVDR) in an effort t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db5cd5e151e60803395e2d22a1f81d69
https://pubmed.ncbi.nlm.nih.gov/29628515
https://pubmed.ncbi.nlm.nih.gov/29628515
Publikováno v:
Future Virology. 10:949-959
ABSTRACT Aim: We examined the literature for the efficacy, safety and tolerability of lopinavir/ritonavir (LPV/r)-based regimens in antiretroviral therapy naive HIV-1-infected subjects with advanced disease. Materials & methods: Virologic and immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c327bfcf0e1ae179d50ffb35da29703
https://doi.org/10.2217/fvl.15.66
https://doi.org/10.2217/fvl.15.66
Autor:
Graham Rickett, Pat Dorr, Mark Holbrook, Michael Mosley, Harriet Sale, Roy Mansfield, Carolyn Napier
Publikováno v:
Biochemical Pharmacology. 71:163-172
The aim of this study was to determine if macaque represents a suitable species for the pre-clinical evaluation of novel CCR5 antagonists, such as maraviroc (UK-427,857). To do this we cloned and expressed CCR5 from rhesus macaque and compared the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c3b95441f8b95798d06b92724c8c69
https://doi.org/10.1016/j.bcp.2005.10.024
https://doi.org/10.1016/j.bcp.2005.10.024
Publikováno v:
Clinical Pharmacology & Therapeutics. 78:508-519
Background The viral dynamics of human immunodeficiency virus (HIV) infection has been widely studied and expressed as mathematic equations. For most of the current registered antiretroviral drugs, the pharmacokinetics is well characterized and some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986fb62982a6dfe9c5a3c16169070a7d
https://doi.org/10.1016/j.clpt.2005.07.010
https://doi.org/10.1016/j.clpt.2005.07.010
Autor:
Elna van der Ryst, Tim M Jenkins, Maria Conceição do Rosário, Philippe Jacqmin, Pat Dorr, Samantha Abel, Ian James
BACKGROUND Maraviroc, a noncompetitive antagonist of the CCR5 coreceptor, was recently approved in the USA as a treatment of HIV infection. For antiretroviral agents that target the virus, antiviral effect can be related to some extent to plasma drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f07263abdb3233cae03a599bbfc2a49
https://europepmc.org/articles/PMC2311409/
https://europepmc.org/articles/PMC2311409/
Publikováno v:
Biochemical pharmacology. 74(6)
Antagonists of the chemokine receptor, CCR5, may provide important new drugs for the treatment of HIV-1. In this study we have examined the mechanism of action of two functional antagonists of the chemokine receptor CCR5 (UK-396,794, UK-438,235) in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6541af73b37808c2c3df927af0e460cb
https://pubmed.ncbi.nlm.nih.gov/17669370
https://pubmed.ncbi.nlm.nih.gov/17669370
Publikováno v:
Nation's Restaurant News. 6/26/95, Vol. 29 Issue 26, p42. 1/9p.
Publikováno v:
Journal of Information Systems. Fall2004, Vol. 18 Issue 2, p7-28. 22p. 8 Charts.