Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pastor R. Couceyro"'
Autor:
Pastor R. Couceyro, Tammi Fritz
Publikováno v:
Protein Expression and Purification. 32:185-193
CART (Cocaine- and Amphetamine-Regulated Transcript) peptides modulate food intake and psychostimulant drug actions. Several CART peptides that contain multiple disulfide bonds were produced by overexpression in Escherichia coli bacteria as fusion pr
Publikováno v:
The Journal of Neuroscience. 21:7474-7480
Administration of cocaine and amphetamine increases cocaine- and amphetamine-regulated transcript (CART) expression in the rat striatum (Douglass et al., 1995). CART mRNA is highly expressed in different parts of the human and rat brain, including hi
Publikováno v:
The Journal of Comparative Neurology. 407:491-511
Cocaine- and amphetamine-regulated transcript (CART) is a novel mRNA whose level of expression was found to be increased in the striatum after acute administration of psychomotor stimulants in rats. To define better the potential role of CART peptide
Autor:
Pastor R. Couceyro, Carol F. Elias, Joseph Kelly, Carl J. Aschkenasi, Rexford S. Ahima, Michael J. Kuhar, Clifford B. Saper, Charlotte E. Lee, Joel K. Elmquist
Publikováno v:
Neuron. 21:1375-1385
The adipocyte-derived hormone leptin decreases body weight in part by activating the sympathetic nervous system, resulting in increased thermogenesis and energy expenditure. We investigated hypothalamic pathways underlying leptin’s effects on stimu
Publikováno v:
Synapse. 30:1-8
Cocaine and amphetamine regulated transcript (CART) encodes a novel brain-enriched protein whose features are reminiscent of a neurotransmitter propeptide. We have now localized CART peptide(s) in the gastrointestinal tract by immunohisto- chemical m
Autor:
Michael J. Kuhar, Kathleen M McGirr, Yoland Smith, Pastor R. Couceyro, Stephanie Dall Vechia, Philip D. Lambert
Publikováno v:
Synapse. 29:293-298
While CART peptides have been implicated as novel, putative peptide neurotransmitters/cotransmitters, behavioral effects of these peptides have not yet been demonstrated. In this study, we show the first behavioral effect of CART peptides. Icv admini
Publikováno v:
The Journal of Comparative Neurology. 391:115-132
Cocaine- and amphetamine-regulated transcript (CART) is a brain-enriched mRNA with a protein product(s) that is a candidate brain neurotransmitter. We have developed antisera to CART peptide fragment 106-129 and have demonstrated specific immunoreact
Publikováno v:
Synapse. 27:90-94
CART (cocaine- and amphetamine-regulated transcript) peptides are proposed to play a role in the action of psychostimulants as neurotransmitters/neuromodulators. In the present study, we demonstrate that the shell of the nucleus accumbens, a brain st
Publikováno v:
NeuroReport. 8:2437-2441
Using differential display PCR, we identified a cDNA whose expression is altered in several brain regions in rats self-administering cocaine. The cDNA sequence corresponds to bases 13687-13723 of the rat NADH dehydrogenase subunit 6 gene. Northern an
Publikováno v:
Journal of Chemical Neuroanatomy. 12:229-241
CART (cocaine and amphetamine regulated transcript) is a novel, brain-enriched mRNA which predicts a novel protein without homology to any known protein or peptide. In situ hybridization studies have identified many expression sites in the brain and