Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.

Autor: Michno W; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, UK., Stringer KM; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, UK., Enzlein T; Center for Mass Spectrometry and Optical Spectroscopy, Mannheim University of Applied Sciences, Mannheim, Germany., Passarelli MK; Laboratory of Biological Geochemistry, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Department of Chemistry and Biochemistry, Concordia University, Montréal, Québec, Canada., Escrig S; Laboratory of Biological Geochemistry, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Vitanova K; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, UK., Wood J; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, UK., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute, University College London, London, UK., Meibom A; Laboratory of Biological Geochemistry, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Center for Advanced Surface Analysis, Institute of Earth Sciences, University of Lausanne, Lausanne, Switzerland., Hopf C; Center for Mass Spectrometry and Optical Spectroscopy, Mannheim University of Applied Sciences, Mannheim, Germany., Edwards FA; Department of Neuroscience, Physiology, and Pharmacology, University College London, London, UK., Hanrieder J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden. jh@gu.se.; Department of Neurodegenerative Disease, Queen Square Institute of Neurology, University College London, London, UK.

Publikováno v: Science advances [Sci Adv] 2021 Jun 16; Vol. 7 (25). Date of Electronic Publication: 2021 Jun 16 (Print Publication: 2021).

OrbiSIMS Imaging Identifies Molecular Constituents of the Perialgal Vacuole Membrane of Paramecium bursaria with Symbiotic Chlorella variabilis .

Autor: Aoyagi S; Department of Materials and Life Science , Seikei University , Tokyo 180-8633 , Japan., Kodama Y; Institute of Agricultural and Life Sciences, Academic Assembly , Shimane University , Matsue , Shimane 690-8504 , Japan., Passarelli MK; National Physical Laboratory , Hampton Road , Teddington , Middlesex TW11 0LW , U.K., Vorng JL; National Physical Laboratory , Hampton Road , Teddington , Middlesex TW11 0LW , U.K., Kawashima T; Corporate Engineering Division, Appliances Company , Panasonic Corporation , Kyoto 619-0237 , Japan., Yoshikiyo K; Institute of Agricultural and Life Sciences, Academic Assembly , Shimane University , Matsue , Shimane 690-8504 , Japan., Yamamoto T; Institute of Agricultural and Life Sciences, Academic Assembly , Shimane University , Matsue , Shimane 690-8504 , Japan., Gilmore IS; National Physical Laboratory , Hampton Road , Teddington , Middlesex TW11 0LW , U.K.

Publikováno v: Analytical chemistry [Anal Chem] 2019 Nov 19; Vol. 91 (22), pp. 14545-14551. Date of Electronic Publication: 2019 Oct 31.

Intracellular Drug Uptake-A Comparison of Single Cell Measurements Using ToF-SIMS Imaging and Quantification from Cell Populations with LC/MS/MS.

Autor: Newman CF; GlaxoSmithKline , Stevenage SG1 2NY, United Kingdom.; Division of Advanced Materials and Healthcare Technologies, School of Pharmacy, University of Nottingham , University Park, Nottingham NG7 2RD, United Kingdom., Havelund R; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL) , Teddington, Middlesex TW11 0LW, United Kingdom., Passarelli MK; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL) , Teddington, Middlesex TW11 0LW, United Kingdom., Marshall PS; GlaxoSmithKline , Stevenage SG1 2NY, United Kingdom., Francis I; GlaxoSmithKline , Stevenage SG1 2NY, United Kingdom., West A; GlaxoSmithKline , Stevenage SG1 2NY, United Kingdom., Alexander MR; Division of Advanced Materials and Healthcare Technologies, School of Pharmacy, University of Nottingham , University Park, Nottingham NG7 2RD, United Kingdom., Gilmore IS; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL) , Teddington, Middlesex TW11 0LW, United Kingdom., Dollery CT; GlaxoSmithKline , Stevenage SG1 2NY, United Kingdom.

Publikováno v: Analytical chemistry [Anal Chem] 2017 Nov 21; Vol. 89 (22), pp. 11944-11953. Date of Electronic Publication: 2017 Nov 08.

Fabrication and characterisation of drug-loaded electrospun polymeric nanofibers for controlled release in hernia repair.

Autor: Hall Barrientos IJ; Biomedical Engineering, University of Strathclyde, Glasgow, United Kingdom; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom., Paladino E; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom; EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation (CMAC), University of Strathclyde, Technology and Innovation Centre, 99 George Street, G1 1RD Glasgow, United Kingdom; National Physical Laboratory (NPL), Hampton Road, Teddington, Middlesex, TW11 0LW, United Kingdom., Brozio S; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom., Passarelli MK; National Physical Laboratory (NPL), Hampton Road, Teddington, Middlesex, TW11 0LW, United Kingdom., Moug S; National Health Service (NHS), Royal Alexandra Hospital, Paisley, PA2 9PN, United Kingdom., Black RA; Biomedical Engineering, University of Strathclyde, Glasgow, United Kingdom., Wilson CG; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom., Lamprou DA; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom; Medway School of Pharmacy, University of Kent, Medway Campus, Anson Building, Central Avenue, Chatham Maritime, Chatham, Kent, ME4 4TB, United Kingdom. Electronic address: d.lamprou@kent.ac.uk.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2017 Jan 30; Vol. 517 (1-2), pp. 329-337. Date of Electronic Publication: 2016 Dec 14.

Chemical intervention in plant sugar signalling increases yield and resilience.

Autor: Griffiths CA; Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK., Sagar R; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Geng Y; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Primavesi LF; Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK., Patel MK; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Passarelli MK; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL), Teddington, Middlesex TW11 0LW, UK., Gilmore IS; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL), Teddington, Middlesex TW11 0LW, UK., Steven RT; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL), Teddington, Middlesex TW11 0LW, UK., Bunch J; National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI), National Physical Laboratory (NPL), Teddington, Middlesex TW11 0LW, UK.; School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK., Paul MJ; Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK., Davis BG; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.

Publikováno v: Nature [Nature] 2016 Dec 22; Vol. 540 (7634), pp. 574-578. Date of Electronic Publication: 2016 Dec 14.