Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pasquale Sileo"'
Autor:
Pasquale Sileo, Clémence Simonin, Patricia Melnyk, Marie-Christine Chartier-Harlin, Philippe Cotelle
Publikováno v:
Cells, Vol 11, Iss 22, p 3631 (2022)
The Hippo pathway consists of a cascade of kinases that controls the phosphorylation of the co-activators YAP/TAZ. When unphosphorylated, YAP and TAZ translocate into the nucleus, where they mainly bind to the TEAD transcription factor family and act
Externí odkaz:
https://doaj.org/article/88352385c66045fe8c08001e4d4ad092
Autor:
Jean-François Guichou, Manon Sturbaut, Romain Magnez, Marie-Christine Chartier-Harlin, Patricia Melnyk, Martine Pugnière, Maxime Liberelle, Pasquale Sileo, Philippe Cotelle, Xavier Thuru, Muriel Gelin, Fabrice Bailly, Mathilde Coevoet, Frédéric Allemand
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2021, 226, pp.113835. ⟨10.1016/j.ejmech.2021.113835⟩
European Journal of Medicinal Chemistry, 2021, 226, pp.113835. ⟨10.1016/j.ejmech.2021.113835⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 226, pp.113835. ⟨10.1016/j.ejmech.2021.113835⟩
European Journal of Medicinal Chemistry, 2021, 226, pp.113835. ⟨10.1016/j.ejmech.2021.113835⟩
International audience; The Hippo pathway is involved in organ size control and tissue homeostasis by regulating cell growth, proliferation and apoptosis. It controls the phosphorylation of the transcription co-activator YAP (Yes associated protein)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7429a293a362569302e5cdb8210bf10b
https://hal.archives-ouvertes.fr/hal-03429462
https://hal.archives-ouvertes.fr/hal-03429462