Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Pasquale Di Carlo"'
Autor:
Ethan Tietze, Andre Rocha Barbosa, Bruno Araujo, Veronica Euclydes, Bailey Spiegelberg, Hyeon Jin Cho, Yong Kyu Lee, Yanhong Wang, Alejandra McCord, Alan Lorenzetti, Arthur Feltrin, Joyce van de Leemput, Pasquale Di Carlo, Gianluca Ursini, Kynon J. Benjamin, Helena Brentani, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Ronald McKay, Joo Heon Shin, Tomoyo Sawada, Apua C. M. Paquola, Jennifer A. Erwin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Primary human trophoblast stem cells (TSCs) and TSCs derived from human pluripotent stem cells (hPSCs) can potentially model placental processes in vitro. Yet, the pluripotent states and factors involved in the differentiation of hPSCs to TS
Externí odkaz:
https://doaj.org/article/6bb7441979f6437cb464f3a0916c266a
Autor:
Gianluca Ursini, Pasquale Di Carlo, Sreya Mukherjee, Qiang Chen, Shizhong Han, Jiyoung Kim, Maya Deyssenroth, Carmen J. Marsit, Jia Chen, Ke Hao, Giovanna Punzi, Daniel R. Weinberger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Our earlier work has shown that genomic risk for schizophrenia converges with early life complications in affecting risk for the disorder and sex-biased neurodevelopmental trajectories. Here, we identify specific genes and potential mechanis
Externí odkaz:
https://doaj.org/article/206d72636ced4f029aed269847f1fd81
Autor:
Eugenia Radulescu, Qiang Chen, Giulio Pergola, Pasquale Di Carlo, Shizhong Han, Joo Heon Shin, Thomas M Hyde, Joel E Kleinman, Daniel R Weinberger
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010989 (2023)
The effect of schizophrenia (SCZ) genetic risk on gene expression in brain remains elusive. A popular approach to this problem has been the application of gene co-expression network algorithms (e.g., WGCNA). To improve reliability with this method it
Externí odkaz:
https://doaj.org/article/5b4e1686789a4b1b9371751ae2a7254d
Autor:
Torbjørn Elvsåshagen, Shahram Bahrami, Dennis van der Meer, Ingrid Agartz, Dag Alnæs, Deanna M. Barch, Ramona Baur-Streubel, Alessandro Bertolino, Mona K. Beyer, Giuseppe Blasi, Stefan Borgwardt, Birgitte Boye, Jan Buitelaar, Erlend Bøen, Elisabeth Gulowsen Celius, Simon Cervenka, Annette Conzelmann, David Coynel, Pasquale Di Carlo, Srdjan Djurovic, Sarah Eisenacher, Thomas Espeseth, Helena Fatouros-Bergman, Lena Flyckt, Barbara Franke, Oleksandr Frei, Barbara Gelao, Hanne Flinstad Harbo, Catharina A. Hartman, Asta Håberg, Dirk Heslenfeld, Pieter J. Hoekstra, Einar A. Høgestøl, Rune Jonassen, Erik G. Jönsson, Karolinska Schizophrenia Project (KaSP) consortium, Peter Kirsch, Iwona Kłoszewska, Trine Vik Lagerberg, Nils Inge Landrø, Stephanie Le Hellard, Klaus-Peter Lesch, Luigi A. Maglanoc, Ulrik F. Malt, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Torgeir Moberget, Jan Egil Nordvik, Lars Nyberg, Kevin S. O’ Connell, Jaap Oosterlaan, Marco Papalino, Andreas Papassotiropoulos, Paul Pauli, Giulio Pergola, Karin Persson, Dominique de Quervain, Andreas Reif, Jaroslav Rokicki, Daan van Rooij, Alexey A. Shadrin, André Schmidt, Emanuel Schwarz, Geir Selbæk, Hilkka Soininen, Piotr Sowa, Vidar M. Steen, Magda Tsolaki, Bruno Vellas, Lei Wang, Eric Westman, Georg C. Ziegler, Mathias Zink, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The genetic architecture underlying brainstem regions and how this links to common brain disorders is not well understood. Here, the authors use MRI and GWAS data from 27,034 individuals to identify genetic and morphological brainstem features that i
Externí odkaz:
https://doaj.org/article/bb60787933434b12ab5b236140b403a3
Autor:
Alfonso Monaco, Anna Monda, Nicola Amoroso, Alessandro Bertolino, Giuseppe Blasi, Pasquale Di Carlo, Marco Papalino, Giulio Pergola, Sabina Tangaro, Roberto Bellotti
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190110 (2018)
Research on brain disorders with a strong genetic component and complex heritability, such as schizophrenia, has led to the development of brain transcriptomics. This field seeks to gain a deeper understanding of gene expression, a key factor in expl
Externí odkaz:
https://doaj.org/article/b8ee77c615514951af55de98110d473a
Autor:
Alexandra Kelly, Jennifer M. Coughlin, Vidyulata Kamath, Anisha Nagpal, Zui Narita, Pasquale Di Carlo, Anshel Kenkare, Andreia V. Faria, Kun Yang, Nicola G. Cascella, Thomas W. Sedlak, Frederick C. Nucifora, Gerald Nestadt, Luisa Longo, Marina Mihaljevic, Peter B. Barker, Akira Sawa, Min Wang, Mehk Sethi
Publikováno v:
Molecular Psychiatry. 27:1184-1191
Treatment resistant (TR) psychosis is considered to be a significant cause of disability and functional impairment. Numerous efforts have been made to identify the clinical predictors of TR. However, the exploration of molecular and biological marker
Autor:
Giovanna Punzi, Gianluca Ursini, Qiang Chen, Eugenia Radulescu, Ran Tao, Louise A. Huuki, Pasquale Di Carlo, Leonardo Collado-Torres, Joo Heon Shin, Roberto Catanesi, Andrew E. Jaffe, Thomas M. Hyde, Joel E. Kleinman, Trudy F.C. Mackay, Daniel R. Weinberger
Publikováno v:
Am J Psychiatry
OBJECTIVE: The authors sought to study the transcriptomic and genomic features of completed suicide by parsing the method chosen, to capture molecular correlates of the distinctive frame of mind of individuals who die by suicide while reducing hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69023ecee58e191679cacc0e75dfbf0d
https://europepmc.org/articles/PMC8908792/
https://europepmc.org/articles/PMC8908792/
Autor:
Roberto Bellotti, Marco Papalino, Alfonso Monaco, Alessandro Bertolino, Raffaella Romano, Paolo Taurisano, Roberta Passiatore, Giulio Pergola, Antonio Rampino, Pasquale Di Carlo, Anna Monda, Annamaria Porcelli, Aurora Bonvino, Linda A. Antonucci, Giuseppe Blasi, Francesco Maria Piarulli, Teresa Popolizio
Publikováno v:
Brain Imaging and Behavior. 15:288-299
Convergent findings indicate that cannabis use and variation in the cannabinoid CB1 receptor coding gene (CNR1) modulate prefrontal function during working memory (WM). Other results also suggest that cannabis modifies the physiological relationship
Autor:
Pasquale Di Carlo, Rita Masellis, Giulio Pergola, Antonio Rampino, Joel E. Kleinman, Maria Pennuto, Alessandro Bertolino, Daniel R. Weinberger, Joo Ho Shin, Silvia Torretta, Manuela Basso, Thomas M. Hyde, Giuseppe Blasi
Publikováno v:
The Journal of Neuroscience. 40:932-941
Multiple schizophrenia (SCZ) risk loci may be involved in gene co-regulation mechanisms, and analysis of coexpressed gene networks may help to clarify SCZ molecular basis. We have previously identified a dopamine D2 receptor (DRD2) coexpression modul
Autor:
Gianluca Ursini, Pasquale Di Carlo, Sreya Mukherjee, Qiang Chen, Giovanna Punzi, Jiyoung Kim, Alessandro Bertolino, Daniel Weinberger
Publikováno v:
European Neuropsychopharmacology. 63:e91