Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Pasqua, O. della"'
1
Akademický článek
Implications of drug-induced phenotypical resistance: Is isoniazid radicalizing M. tuberculosis?
Autor: Hammond, R. J. H., Kloprogge, Frank, Pasqua, O. Della, Gillespie, Stephen H.
Publikováno v: Frontiers in Antibiotics; 9/9/2022, Vol. 1, p01-12, 12p
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3
A model-based approach for the evaluation of once daily dosing of lamivudine in HIV-infected children
Autor: Piana, C., Zhao, W., Adkison, K., Burger, D.M., Jacqz-Aigrain, E., Danhof, M., Pasqua, O. Della
Publikováno v: British Journal of Clinical Pharmacology, 77, 852-60
British Journal of Clinical Pharmacology; Vol 77
British Journal of Clinical Pharmacology, 77, 5, pp. 852-60
Item does not contain fulltext AIM: Little attention has been paid to the effects of compliance and prescription practice on treatment outcome in HIV-infected children. In this context, an evaluation of the role of covariates on pharmacokinetics is r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::49e1f36f5f7ac78dacd41be6f945d679
https://europepmc.org/articles/PMC4004405/
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4
Covariate effects and population pharmacokinetics of lamivudine in HIV-infected children
Autor: Piana, C., Zhao, W., Adkison, K., Burger, D.M., Jacqz-Aigrain, E., Danhof, M., Pasqua, O. Della
Publikováno v: British Journal of Clinical Pharmacology, 77, 861-72
British Journal of Clinical Pharmacology, 77, 5, pp. 861-72
Item does not contain fulltext AIM: Lamivudine is used as first line therapy in HIV-infected children. Yet, like many other paediatric drugs, its dose rationale has been based on limited clinical data, without thorough understanding of the effects of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::00c8b489b7e612e83e0fc3a98f8a6adf
http://hdl.handle.net/2066/136234
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5
Scaling of pharmacokinetics across paediatric populations: the lack of interpolative power of allometric models
Autor: Cella, M., Knibbe, C., Wildt, S.N. de, Gerven, J. van, Danhof, M., Pasqua, O. della
Publikováno v: British Journal of Clinical Pharmacology, 74(3), 525-535. Wiley-Blackwell Publishing Ltd
British Journal of Clinical Pharmacology
Aims: The objective of this investigation was to assess the performance of an allometric model as the basis for interpolating drug exposure in the context of pharmacokinetic bridging across paediatric subpopulations. Methods: Midazolam was selected a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eac473081b0de93d8103ef7aa8bfe14a
https://pure.eur.nl/en/publications/b27a6b36-d4ee-48ba-a43e-0ecf5baaeed7
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6
Population pharmacokinetics and maximum a posteriori probability Bayesian estimator of abacavir: application of individualized therapy in HIV-infected infants and toddlers
Autor: Zhao, W., Cella, M., Pasqua, O. Della, Burger, D.M., Jacqz-Aigrain, E.
Publikováno v: British Journal of Clinical Pharmacology, 73, 641-50
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology; Vol 73
British Journal of Clinical Pharmacology, 73, 4, pp. 641-50
Item does not contain fulltext WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Abacavir is used to treat HIV infection in both adults and children. The recommended paediatric dose is 8 mg kg(-1) twice daily up to a maximum of 300 mg twice daily. Weight was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::13479fe883a68e252d80ef4719980599
http://hdl.handle.net/2066/109091
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7
Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats
Autor: Huntjens, D R H, Strougo, A, Chain, A, Metcalf, A, Summerfield, S, Spalding, D J M, Danhof, M, Pasqua, O Della
Enterohepatic recirculation (EHC) is a common pharmacokinetic phenomenon that has been poorly modelled in animals. The presence of EHC leads to the appearance of multiple peaks in the concentration-time profile and increased exposure, which may have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::33111c690eb386414ad6626ab8cdee61
https://europepmc.org/articles/PMC2267282/
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8
Akademický článek
A Model-Based Approach to Dose Selection in Early Pediatric Development.
Autor: Cella, M., de Vries, F. Gorter, Burger, D., Danhof, M., Pasqua, O. Della
Publikováno v: Clinical Pharmacology & Therapeutics; Mar2010, Vol. 87 Issue 3, p294-302, 9p, 3 Charts, 4 Graphs
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