Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pasit Phiasivongsa"'
Autor:
Sibel Ucpinar, Borje Darpo, Ann Neale, Philip Nunn, Jin Shu, Katherine A. Chu, Marianne Kavanagh, Hongqi Xue, Pasit Phiasivongsa, Dolca Thomas, Patrick F. Smith
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 6, Pp 1507-1518 (2022)
Abstract This study aimed to define the clinically relevant supratherapeutic dose of rilzabrutinib, an oral Bruton tyrosine kinase (BTK) inhibitor, and evaluate potential effects of therapeutic and supratherapeutic exposures on cardiac repolarization
Externí odkaz:
https://doaj.org/article/3418278264b64f71bc273037eb1ad05f
Autor:
Samson T. Jacob, Sanjeev Redkar, Pasit Phiasivongsa, Darby G. Brooke, Swarna A. Gamage, William A. Denny, Kalpana Ghoshal, Jharna Datta
Supplementary Methods and Figure Legends 1-2 from A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3799b309d50b587234700ace1d5b600a
https://doi.org/10.1158/0008-5472.22377986.v1
https://doi.org/10.1158/0008-5472.22377986.v1
Autor:
Samson T. Jacob, Sanjeev Redkar, Pasit Phiasivongsa, Darby G. Brooke, Swarna A. Gamage, William A. Denny, Kalpana Ghoshal, Jharna Datta
Supplementary Figures 1-2 from A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb8f2680f40d7788cefd637c2cc0cb9
https://doi.org/10.1158/0008-5472.22377989.v1
https://doi.org/10.1158/0008-5472.22377989.v1
Autor:
Sibel, Ucpinar, Borje, Darpo, Ann, Neale, Philip, Nunn, Jin, Shu, Katherine A, Chu, Marianne, Kavanagh, Hongqi, Xue, Pasit, Phiasivongsa, Dolca, Thomas, Patrick F, Smith
Publikováno v:
Clinical and Translational Science. 15:1507-1518
This study aimed to define the clinically relevant supratherapeutic dose of rilzabrutinib, an oral Bruton tyrosine kinase (BTK) inhibitor, and evaluate potential effects of therapeutic and supratherapeutic exposures on cardiac repolarization in healt
Autor:
Pasit Phiasivongsa, Matthew C Foulke, Jyoti Wadhwa, J. Michael Bradshaw, Kolbot By, Natalie Loewenstein, Jiang Zhu, Jin Shu, Yan Xing, Claire L. Langrish, Katherine Chu, Philip A. Nunn, David Michael Goldstein, Wei Chen
Publikováno v:
ImmunoHorizons. 5:581-589
The expression of Bruton tyrosine kinase (BTK) in B cells and innate immune cells provides essential downstream signaling for BCR, Fc receptors, and other innate immune cell pathways. The topical covalent BTK inhibitor PRN473 has shown durable, rever
Autor:
Janet Chin, Yogen Saunthararajah, Pasit Phiasivongsa, Donald Lavelle, Roselle Will, Mahipal Singh, Kestis Vaitkus, Chunlin Tang, Maria Hankewych, Joseph DeSimone, Sanjeev Redkar, Bryan P. Roxas
Publikováno v:
American Journal of Hematology. 82:981-985
The silencing of tumor suppressor genes associated with increased DNA methylation of the promoter regions is a frequent observation in many forms of cancer. Reactivation of these genes using pharmacological inhibitors of DNA methyltransferase such as
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 44:4328-4337
Three different characterization methods- 13 C NMR spectroscopy, a terminal terpolymerization model, and a probability analysis based on the Poisson distribution-were used to determine the microstructure of random terpolymers. The methods were used t
Publikováno v:
Tetrahedron Letters. 44:5495-5498
Mechanistic intermediates, and thermodynamically favored side products, in the Henry condensations of partially protected and non-protected pyranoses with a free anomeric hemiacetal function with nitromethane in various solvents for the kinetically c
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 42:317-325
The copolymerization and terpolymerization of leucine-N-carboxyanhydride, β-benzyl aspartate-N-carboxyanhydride, and valine-N-carboxyanhydride in dioxane, initiated with triethylamine, were investigated to determine the random nature of the terpolym
Autor:
Paul H. Gross, Chang-Nan Chen, Patrick R. Jones, Pasit Phiasivongsa, Julie Gallagher, Vyacheslav V. Samoshin
Publikováno v:
Organic Letters. 4:4587-4590
[reaction: see text] Synthesis of glycosyl cyanides was optimized with a new catalyst system. Reduction of tri-O-acetyl-beta-L-fucopyranosyl cyanide with Pd-hydrogen, in the presence of Ac(2)O and Boc(2)O, gave N-protected-mono- and -di-(2,3,4-tri-O-