Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults.

Autor: Jongo SA; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Church LWP; Sanaria Inc., Rockville, Maryland., Nchama VUNN; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Hamad A; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Chuquiyauri R; Sanaria Inc., Rockville, Maryland., Kassim KR; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Athuman T; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Deal A; Clinical Immunology Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Natasha KC; Sanaria Inc., Rockville, Maryland.; Protein Potential LLC, Rockville, Maryland., Mtoro A; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Mpina M; Clinical Immunology Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Nyakarungu E; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Bidjimi GO; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Owono MA; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Mayé ERM; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Mangue MEO; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Okomo GNN; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Pasialo BEN; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Mandumbi DMO; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Mikue MAL; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Mochomuemue FL; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Obono MO; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Besahá JCM; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Bijeri JR; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Abegue GM; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Veri YR; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Bela IT; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Chochi FC; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Lima Sánchez JE; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Pencelli V; Sanaria Inc., Rockville, Maryland., Gayozo G; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Nlang JAEM; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Schindler T; Clinical Immunology Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., James ER; Sanaria Inc., Rockville, Maryland., Abebe Y; Sanaria Inc., Rockville, Maryland., Lemiale L; Sanaria Inc., Rockville, Maryland., Stabler TC; Sanaria Inc., Rockville, Maryland., Murshedkar T; Sanaria Inc., Rockville, Maryland., Chen MC; Sanaria Inc., Rockville, Maryland., Schwabe C; Medical Care Development International (MCDI), Silver Spring, Maryland., Ratsirarson J; Medical Care Development International (MCDI), Silver Spring, Maryland., Rivas MR; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Ayekaba MO; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Milang DVN; Ministry of Health and Social Welfare, Equatorial Guinea, Malabo, Equatorial Guinea., Falla CC; Medical Care Development International (MCDI), Silver Spring, Maryland., Phiri WP; Medical Care Development International (MCDI), Silver Spring, Maryland., García GA; Medical Care Development International (MCDI), Silver Spring, Maryland., Maas CD; Marathon EG Production, Ltd., Bioko Norte, Equatorial Guinea., Nlavo BM; Marathon EG Production, Ltd., Bioko Norte, Equatorial Guinea., Tanner M; Clinical Immunology Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Billingsley PF; Sanaria Inc., Rockville, Maryland., Kim Lee Sim B; Sanaria Inc., Rockville, Maryland.; Protein Potential LLC, Rockville, Maryland., Daubenberger C; Clinical Immunology Unit, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Hoffman SL; Sanaria Inc., Rockville, Maryland., Abdulla S; Bagamoyo Research and Training Center, Ifakara Health Institute, Bagamoyo, Tanzania., Richie TL; Sanaria Inc., Rockville, Maryland.

Publikováno v: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2022 Feb 07; Vol. 106 (4), pp. 1215-1226. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).