Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition.

Autor: Elsakr JM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Dunn JC; Department of Veterans Affairs Tennessee Valley, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Tennant K; Division of Cardiometabolic Health, Oregon National Primate Research Center, Beaverton, OR, USA., Zhao SK; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Kroeten K; Vanderbilt Summer Diabetes Research Program, Vanderbilt University, Nashville, TN, USA., Pasek RC; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Takahashi DL; Division of Cardiometabolic Health, Oregon National Primate Research Center, Beaverton, OR, USA., Dean TA; Division of Cardiometabolic Health, Oregon National Primate Research Center, Beaverton, OR, USA., Velez Edwards DR; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biomedical Informatics, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., McCurdy CE; Department of Human Physiology, University of Oregon, Eugene, OR, 97403, USA., Aagaard KM; Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine, Houston, TX, 77030, USA., Powers AC; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Veterans Affairs Tennessee Valley, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Friedman JE; Department of Pediatrics, Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA., Kievit P; Division of Cardiometabolic Health, Oregon National Primate Research Center, Beaverton, OR, USA., Gannon M; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA; Department of Veterans Affairs Tennessee Valley, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Cell and Developmental Biology, Vanderbilt University, USA. Electronic address: maureen.gannon@vanderbilt.edu.

Publikováno v: Molecular metabolism [Mol Metab] 2019 Jul; Vol. 25, pp. 73-82. Date of Electronic Publication: 2019 Apr 12.

Vascular-derived connective tissue growth factor (Ctgf) is critical for pregnancy-induced β cell hyperplasia in adult mice.

Autor: Pasek RC; a Department of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA., Dunn JC; a Department of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA., Elsakr JM; b Department of Molecular Physiology and Biophysics , Vanderbilt University , Nashville , TN , USA., Aramandla M; c School for Science and Math, Vanderbilt University , Nashville , TN , USA., Matta AR; c School for Science and Math, Vanderbilt University , Nashville , TN , USA., Gannon M; a Department of Medicine , Vanderbilt University Medical Center , Nashville , TN , USA.; b Department of Molecular Physiology and Biophysics , Vanderbilt University , Nashville , TN , USA.; d Department of Veterans Affairs Tennessee Valley , Nashville , TN , USA.; e Department of Cell and Developmental Biology , Vanderbilt University , Nashville , TN , USA.

Publikováno v: Islets [Islets] 2017 Nov 02; Vol. 9 (6), pp. 150-158. Date of Electronic Publication: 2017 Nov 07.

Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres.

Autor: Pasek RC; Department of Medicine, Vanderbilt University Medical Center., Kavanaugh TE; School of Engineering, Vanderbilt University., Duvall CL; School of Engineering, Vanderbilt University., Gannon MA; Department of Medicine, Vanderbilt University Medical Center; Department of Veterans Affairs, Tennessee Valley Health Authority; maureen.gannon@vanderbilt.edu.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2016 Nov 05 (117). Date of Electronic Publication: 2016 Nov 05.

Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.

Autor: Lewis WR; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Malarkey EB; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Tritschler D; Genetics, Cell Biology, and Development, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America., Bower R; Genetics, Cell Biology, and Development, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America., Pasek RC; Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States of America., Porath JD; Division of Nephrology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America., Birket SE; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Saunier S; INSERM, U-983, Necker Hospital, Paris, France.; Paris Descartes University, Sorbonne Paris Cité, Imagine Institute, Paris, France., Antignac C; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1163, Laboratory of Hereditary Kidney Diseases, Paris, France.; Assistance Publique-Hôpitaux de Paris, Department of Genetics, Necker Hospital, Paris, France., Knowles MR; Department of Medicine, UNC School of Medicine, Marisco Lung Institute, Chapel Hill, North Carolina, United States of America., Leigh MW; Department of Pediatrics, UNC School of Medicine, Marisco Lung Institute, Chapel Hill, North Carolina, United States of America., Zariwala MA; Department of Pathology and Laboratory Medicine, UNC School of Medicine, Marisco Lung Institute, Chapel Hill, North Carolina, United States of America., Challa AK; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Kesterson RA; Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Rowe SM; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Drummond IA; Nephrology Division, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America., Parant JM; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Hildebrandt F; Division of Nephrology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America., Porter ME; Genetics, Cell Biology, and Development, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America., Yoder BK; Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Berbari NF; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2016 Jul 29; Vol. 12 (7), pp. e1006220. Date of Electronic Publication: 2016 Jul 29 (Print Publication: 2016).

Macrophages are essential for CTGF-mediated adult β-cell proliferation after injury.

Autor: Riley KG; Department of Cell and Developmental Biology at Vanderbilt University, Nashville, TN, USA., Pasek RC; Department of Medicine at Vanderbilt University, Nashville, TN, USA., Maulis MF; Department of Medicine at Vanderbilt University, Nashville, TN, USA., Dunn JC; Department of Medicine at Vanderbilt University, Nashville, TN, USA., Bolus WR; Department of Veterans Affairs, Tennessee Valley Health Authority, Nashville, TN, USA ; Departments of Molecular Physiology and Biophysics at Vanderbilt University, Nashville, TN, USA., Kendall PL; Department of Medicine at Vanderbilt University, Nashville, TN, USA., Hasty AH; Department of Veterans Affairs, Tennessee Valley Health Authority, Nashville, TN, USA ; Departments of Molecular Physiology and Biophysics at Vanderbilt University, Nashville, TN, USA., Gannon M; Department of Veterans Affairs, Tennessee Valley Health Authority, Nashville, TN, USA ; Department of Cell and Developmental Biology at Vanderbilt University, Nashville, TN, USA ; Department of Medicine at Vanderbilt University, Nashville, TN, USA ; Departments of Molecular Physiology and Biophysics at Vanderbilt University, Nashville, TN, USA.

Publikováno v: Molecular metabolism [Mol Metab] 2015 May 19; Vol. 4 (8), pp. 584-91. Date of Electronic Publication: 2015 May 19 (Print Publication: 2015).