Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia.

Autor: Klintman J; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Translational Medicine, Skåne University Hospital, Lund University, Lund, Sweden., Appleby N; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Hematology, Oxford University Hospitals National Health Service (NHS) Trust, Oxford, United Kingdom., Stamatopoulos B; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Laboratory of Clinical Cell Therapy, Jules Bordet Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium., Ridout K; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom., Eyre TA; Department of Hematology, Oxford University Hospitals National Health Service (NHS) Trust, Oxford, United Kingdom., Robbe P; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom., Pascua LL; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom., Knight SJL; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Dreau H; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom., Cabes M; Department of Hematology, Oxford University Hospitals National Health Service (NHS) Trust, Oxford, United Kingdom., Popitsch N; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; The Children's Cancer Research Institute (CCRI), Vienna, Austria., Ehinger M; Pathology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden., Martín-Subero JI; Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Campo E; Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain., Månsson R; Center for Hematology and Regenerative Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Hematology Center, Karolinska University Hospital, Stockholm, Sweden; and., Rossi D; Institute of Oncology Research (IOR), Bellinzona, Switzerland., Taylor JC; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Vavoulis DV; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Schuh A; Molecular Diagnostic Centre, Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Oncology, University of Oxford, Oxford, United Kingdom.; Department of Hematology, Oxford University Hospitals National Health Service (NHS) Trust, Oxford, United Kingdom.; National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

Publikováno v: Blood [Blood] 2021 May 20; Vol. 137 (20), pp. 2800-2816.