Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pascaline Mary"'
Autor:
Andrew D. Griffiths, Alexei Godina, Guillaume Mottet, Gaël A. Millot, Bingqing Shen, Samantha N. Stewart, Vera Menrath, Sosthene Essono, Baptiste Saudemont, Clément Nizak, Annabelle Gérard, Antoine Sautel-Caillé, Scott McNamara, Matthieu Delince, Sami Ellouze, Jean Baudry, Marcel Reichen, Pablo Canales-Herrerias, Charina Ortega, Patrick England, Carlos Castrillon, Odile Richard-Le Goff, Colin Brenan, Klaus Eyer, Pascaline Mary, Luis Briseño-Roa, Allan Jensen, Pierre Bruhns, Raphael Clement Li-Ming Doineau, Adam Woolfe, Roshan Kumar, Bin Jia, Bruno Iannascoli, Yannick Pousse, Kevin Grosselin, Gregory Rose, Adeline Poitou
Publikováno v:
Nature Biotechnology
Nature Biotechnology, 2020, 38, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, Nature Publishing Group, 2020, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, 38
Nature Biotechnology, 2020, 38, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, Nature Publishing Group, 2020, pp.715-721. ⟨10.1038/s41587-020-0466-7⟩
Nature Biotechnology, 38
International audience; Mining the antibody repertoire of plasma cells and plasmablasts could enable the discovery of useful antibodies for therapeutic or research purposes1. We present a method for high-throughput, single-cell screening of IgG-secre
Autor:
Pascaline Mary, Yuan Wang, Bingqing Shen, Yujie Tian, Ruina Jin, Ruikun Wang, Ruonan Li, He Zhou, Mengshi Huang, Wei Wang, Hongkai Zhang, Youjia Cao, Na Li, Fubin Li, Peixiang Ma, Pan Fang, Shanshan Wang, Yingjie Zhao, Liang Schweizer
Publikováno v:
Science Advances
Microfluidics system enables high-throughput functional screening of antibodies for cancer immunotherapy.
Currently, high-throughput approaches are lacking in the isolation of antibodies with functional readouts beyond simple binding. This situa
Currently, high-throughput approaches are lacking in the isolation of antibodies with functional readouts beyond simple binding. This situa
Autor:
Pan Fang, Fubin Li, Yuan Wang, He Zhou, Wei Wang, Hongkai Zhang, Bingqing Shen, Ruina Jin, Mengshi Huang, Peixiang Ma, Ruonan Li, Shanshan Wang, Yingjie Zhao, Ruikun Wang, Liang Schweizer, Na Li, Youjia Cao, Pascaline Mary
Currently high throughput approaches are lagged for isolation of antibodies whose function goes beyond simple binding, which have prevented the next generation cancer immunotherapeutics, such as bispecific T cell engager antibodies or agonist antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8392b65b25b47765e56df2b5dc6ee1a
https://doi.org/10.1101/2020.11.25.399188
https://doi.org/10.1101/2020.11.25.399188
Autor:
Samantha N. Stewart, Annabelle Gérard, Bingqing Shen, Colin Brenan, Pascaline Mary, Matthieu Delince, Scott McNamara, Klaus Eyer, Guillaume Mottet, Sami Ellouze, Pierre Bruhns, Adam Woolfe, Pablo Canales-Herrerias, Charina Ortega, Antoine Sautel-Caillé, Carlos Castrillon, Raphael Clement Li-Ming Doineau, Jean Baudry, Allan Jensen, Odile Richard-Le Goff, Clément Nizak, Bruno Iannascoli, Vera Menrath, Gregory Rose, Adeline Poitou, Luis Briseño-Roa, Yannick Pousse, Bin Jia, Roshan Kumar, Marcel Reichen, Baptiste Saudemont, Alexei Godina, Patrick England, Kevin Grosselin, Gaël A. Millot, Sosthene Essono, Andrew D. Griffiths
Publikováno v:
Nature biotechnology. 38(6)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Jia Wu, Andreas Raue, Ouyang Li, Zachary Duda, Ross B. Fulton, Alexandra Staskus, Pascaline Mary, Charina Ortega, Ruina Jin, Francisco Adrian, Mingfang Feng, Qian Zhang, Juliana Crivello, Joyce Pi, Nicola Beltraminelli, Matthieu Delince, Hongkai Zhang, Yuan Wang, Yun-Yueh Lu, Minmin Lu, Surendar Arumugam, Liang Schweizer
Publikováno v:
Cancer Research. 80:2285-2285
Agonistic antibodies against the co-stimulatory receptor OX-40 have shown promising activity in preclinical models, but clinical activity has only been observed in isolated cases. While co-stimulation of T cells is described as the primary pharmacolo
Autor:
Dean Lee, Juying Li, Roshan Kumar, He Zhou, Shuo Wei, Francisco Adrian, Charina Ortega, Stephanie Beq, Nicola Beltraminelli, Pascaline Mary, Liang Schweizer, Greg Rose, Qian Zhang, Guang Yang, Matthieu Delince
Publikováno v:
Cancer Research. 80:2282-2282
TNFR2 has recently emerged as a promising therapeutic target for Immuno-Oncology. TNFR2 expression on regulatory and effector T cells in the tumor microenvironment has been associated with T cell exhaustion and resistance to immune-checkpoint blockad
Publikováno v:
Proceedings of the National Academy of Sciences. 107:19163-19166
Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of re
Autor:
Florent Malloggi, Bernard Cabane, Pascaline Mary, Pascal Poncet, Rafaële Attia, Nicolas Pannacci, Fabrice Monti, Patrick Tabeling, Hervé Willaime
Publikováno v:
Langmuir. 26:2369-2373
Limitations in the methods employed to generate micrometric colloidal droplets hinder the emergence of key applications in the fields of material science and drug delivery. Through the use of dedicated nanofluidic devices and by taking advantage of a
Publikováno v:
Microfluidics and Nanofluidics. 8:755-765
The purpose of this study has been to demonstrate the possibilities of uniform heating of a cavity, with great accuracy, by means of an integrated resistor built with the same dimensions as the cavity, i.e., with a high level of integration. For appl
Publikováno v:
The Journal of Physical Chemistry B. 111:7767-7777
We investigate the water-solubility upon salt additions, of homogeneous families of sulfobetaine-based polyzwitterions. These polymers bear both positive ammonium, and negative sulfonate charges on each monomer and as a result present an upper critic