Výsledky vyhledávání - "Pascale Van Belle"

Akademický článek

Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

To elucidate the role of innate responses in vaccine immunogenicity, we compared early responses to hepatitis B virus (HBV) surface antigen (HBsAg) combined with different Adjuvant Systems (AS) in healthy HBV-naïve adults, and included these paramet

Externí odkaz: https://doaj.org/article/65af7ce2d89547bb915bf9bedc2e9b49

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Impact of adjuvants on CD4+ T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial

Publikováno v: Clinical immunology
Clinical Immunology, Vol. 169, p. 16-27 (2016)
CLINICAL IMMUNOLOGY
Clinical immunology, 169

Immunogenicity and safety of different adjuvants combined with a model antigen (HBsAg) were compared. Healthy HBV-naïve adults were randomized to receive HBs adjuvanted with alum or Adjuvant Systems AS01B, AS01E, AS03A or AS04 at Days 0 and 30. Diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39e0ecf25bd251fae9ba1eabfbc0d3a

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Safety and immunogenicity of an investigational 4-componentStaphylococcus aureusvaccine with or without AS03Badjuvant: Results of a randomized phase I trial

Autor: Edwige Haelterman, Philippe Moris, Laurent Licini, Jack Levy, Dominique Boutriau, Pascale Van Belle, Silvia Damaso, Pascal Lestrate

Publikováno v: Human Vaccines & Immunotherapeutics

We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid (TT), with mutated detoxified α-toxin (AT) and clumping factor A (ClfA). In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2358e7224117d1e0ff5ac26beeaf9382
https://doi.org/10.1080/21645515.2015.1011021

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Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at least 4 years after vaccination

Autor: Michel Janssens, Marcelle Van Mechelen, Nathalie Garçon, Isabelle Carletti, Pierre Vandepapelière, Geert Leroux-Roels, Martine Wettendorff, Yves Horsmans, Pascale Van Belle

Publikováno v: VACCINE

Background Recombinant hepatitis B surface antigen (HBsAg) was used as a model antigen to evaluate persistence of cellular and humoral immune responses when formulated with three different Adjuvant Systems containing 3- O -desacyl-4′-monophosphoryl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7645617a7211220e08d572b08bd87a33

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Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: Randomised, controlled trials

Autor: Pascale Van Belle, Pierre Vandepapelière, Yves Horsmans, Philippe Moris, Jeanne-Marie Devaster, Vincent Verlant, Jan Poolman, Philippe Hermand, Geert Leroux-Roels, Isabel Leroux-Roels, Isabelle Henckaerts

Publikováno v: Vaccine. 33:577-584

BackgroundThe protection elicited by polysaccharide pneumococcal vaccines against community-acquired pneumonia in older adults remains debatable. Alternative vaccine targets include well-conserved pneumococcal protein antigens, such as pneumococcal h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8b4d4d4ddde30ab303aebc8a76685b
https://doi.org/10.1016/j.vaccine.2013.10.052

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Randomized controlled study of the safety and immunogenicity of pneumococcal vaccine formulations containing PhtD and detoxified pneumolysin with alum or adjuvant system AS02V in elderly adults

Autor: Pascale Van Belle, Vincent Verlant, Thierry G. Pascal, Magalie Caubet, Karlis Pauksens, Pierre Vandepapelière, Anna Nilsson, Peter Vink, Jan Poolman

Publikováno v: Clinical and vaccine immunology : CVI. 21(5)

Six vaccine formulations containing AS02 V or alum (aluminum phosphate [AlPO 4 ]) adjuvant with pneumococcal proteins, pneumococcal histidine triad D (PhtD), and/or detoxified pneumolysin (dPly), either as a polysaccharide carrier in an 8-valent pneu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d518bdbf9bca324608479e4d089baa
https://pubmed.ncbi.nlm.nih.gov/24599529

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Challenge of conducting a placebo-controlled randomized efficacy study for influenza vaccine in a season with low attack rate and a mismatched vaccine B strain: a concrete example

Autor: Veronika Wertzova, Jeanne-Marie Devaster, Pascale Van Belle, Eva Kaliskova, Bruce L. Innis, Helena Jirincova, Jiří Beran, Martina Havlíčková, Jiří Havlík, Karel Honegr, Varsha K. Jain

Publikováno v: BMC Infectious Diseases, Vol 9, Iss 1, p 2 (2009)
BMC Infectious Diseases

Background Our aim was to determine the efficacy of a trivalent inactivated split virus influenza vaccine (TIV) against culture-confirmed influenza A and/or B in adults 18 to 64 years of age during the 2005/2006 season in the Czech Republic. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07eeb2f3f5ad97b15de077093af4c9e
https://doi.org/10.1186/1471-2334-9-2

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