Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Pascale Reidenberg"'
Autor:
Philip Beale, D. L. Cutler, Ian Judson, Pascale Reidenberg, Vijay Batra, Michael Brada, Sally Moore, Margaret Dugan, Paul Statkevich
Publikováno v:
British Journal of Cancer
Temozolomide, an oral cytotoxic agent with approximately 100% bioavailability after one administration, has demonstrated schedule-dependent clinical activity against highly resistant cancers. Thirty patients with minimal prior chemotherapy were enrol
Autor:
Pascale Reidenberg, A Marco, Ian Lewis, Adj Pearson, M Mott, S Ablett, Vijay Batra, C. Dicks-Mireaux, R. Gowing, Linda S Lashford, Bruce Morland, Richard F. Stevens, Mcg Stevens, CR Pinkerton, J.A. Kohler, Margaret Dugan, A Gholkar, D. Walker, L. Price, Heather P. McDowell, Paul Statkevich, EJ Estlin, Newell
Publikováno v:
British Journal of Cancer. 78:652-661
A phase I study of temozolomide administered orally once a day, on 5 consecutive days, between 500 and 1200 mg m(-2) per 28-day cycle was performed. Children were stratified according to prior craniospinal irradiation or nitrosourea therapy. Sixteen
Autor:
Lucy Shneyer, Pascale Reidenberg, Chin-Chung Lin, Elaine Radwanski, Melvin D. Brannan, Mitchell N. Cayen, Melton B. Affrime
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:269-278
Objective To evaluate the effects of coadministration of loratadine and erythromycin on the pharmacokinetics and electrocardiographic repolarization (QTc) pharmacodynamics of loratadine and its metabolite descarboethoxyloratadine in healthy volunteer
Autor:
James Nezamis, Michel Guillaume, Pascale Reidenberg, Melton B. Affrime, Elaine Radwanski, Parviz Mojavarian, Christopher Banfield, Robert D. Colucci, Jeffrey W. Meehan, Paul Glue, Chin-Chung Lin
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:279-287
The effects of felbamate on the pharmacokinetics of phenobarbital and one of its main metabolites, parahydroxyphenobarbital, were assessed in a parallel-group, placebo-controlled, double-blind study, in 24 healthy volunteers. Pharmacokinetic paramete
Autor:
Eric K. Rowinsky, Kelly Forral, Geoffrey R. Weiss, Sharyn D. Baker, Margaret Dugan, John R. Eckardt, Daniel D. Von Hoff, David Rinaldi, Pascale Reidenberg, Lisa A. Hammond, S. Gail Eckhardt, Paul Statkevich
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 17(8)
PURPOSE: To determine the principal toxicities, characterize the pharmacokinetics (PKs) and pharmacodynamics (PDs) of temozolomide (TMZ) on a daily-for-5-days schedule, and recommend a dose for subsequent disease-directed studies in both minimally pr
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 80(1)
The efficacy and safety of regular-strength beclomethasone dipropionate MDI prescribed within its recommended dosing range of 2 to 5 puffs three to four times daily has been well established in more than 25 years of worldwide use. A more concentrated
Autor:
Jeffrey W. Meehan, Amin A. Nomeir, Christopher Banfield, Melton B. Affrime, Jensen Peder K, Elaine Radwanski, Pertti Haring, Veijo Saano, Pascale Reidenberg, Paul Glue, Chin-Chung Lin, Robert D. Colucci
Publikováno v:
Clinical pharmacology and therapeutics. 58(5)
The effects of felbamate on the pharmacokinetics of a low-dose combination oral contraceptive containing 30 micrograms ethinyl estradiol and 75 micrograms gestodene were assessed in a randomized, double-blind, placebo-controlled parallel-group study
Autor:
Chin-Chung Lin, Christopher Banfield, Jacques A.R.J. Hulsman, Melton B. Affrime, Pascale Reidenberg, James Nezamis, Theo W. Rentmeester, Elaine Radwanski, Robert D. Colucci, Jeffrey W. Meehan, Parviz Mojaverian, Paul Glue
Publikováno v:
Clinical pharmacology and therapeutics. 58(4)
The effects of felbamate on the multiple dose pharmacokinetics of the monohydroxy and dihydroxy metabolites of oxcarbazepine were assessed in a placebo-controlled, randomized, double-blind crossover study in 18 healthy male volunteers. Oxcarbazepine,
Publikováno v:
Clinical therapeutics. 17(4)
The potential for a newly developed, double-strength (0.084%) beclomethasone dipropionate (BDP) aqueous (AQ) nasal suspension to produce effects associated with exposure to systemic corticosteroids was assessed by the plasma cortisol response to cosy
Autor:
Chin-Chung Lin, Pascale Reidenberg, W. Sulowicz, Jeffrey W. Meehan, D.P. Glue, Robert D. Colucci, M.B. Affrime, Christopher Banfield, Sudhakar Pai
Publikováno v:
Clinical Pharmacology & Therapeutics. 59:185-185