Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Pascale R. Leroueil"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283977 (2023)
Although vaccination is widely considered one of the most cost-effective health interventions available, global coverage rates for many vaccines remain lower than necessary for disease elimination and eradication. New vaccine technologies can play an
Externí odkaz:
https://doaj.org/article/925286a1ce7d4f08a06c2fa117f4b610
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263612 (2022)
Vaccines are one of the most cost-effective tools for improving human health and well-being. The impact of a vaccine on population health is partly determined by its coverage rate, the proportion of eligible individuals vaccinated. Coverage rate is a
Externí odkaz:
https://doaj.org/article/afec21577bbc40a6af24ceec91b10035
Autor:
Nora Phillips-White, Pascale R. Leroueil, Ana Costache, Mariam Zameer, Dorothy Thomas, Michael Krautmann
Publikováno v:
Global Health: Science and Practice
The Rapid Supply Chain Modeling Tool enables health system leaders to quickly estimate and compare the cost impact of potential supply chain design improvements in situations where time and budget do not allow for more in-depth modeling approaches.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b6c70b31212cffe0bb02dac581cbb7
https://doi.org/10.9745/ghsp-d-20-00227
https://doi.org/10.9745/ghsp-d-20-00227
Autor:
Pamela T Wong, Pascale R Leroueil, Douglas M Smith, Susan Ciotti, Anna U Bielinska, Katarzyna W Janczak, Catherine H Mullen, Jeffrey V Groom, Erin M Taylor, Crystal Passmore, Paul E Makidon, Jessica J O'Konek, Andrzej Myc, Tarek Hamouda, James R Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126120 (2015)
Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosa
Externí odkaz:
https://doaj.org/article/4084c3c916ea48baa41149fcafb14c47
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263612 (2022)
Vaccines are one of the most cost-effective tools for improving human health and well-being. The impact of a vaccine on population health is partly determined by its coverage rate, the proportion of eligible individuals vaccinated. Coverage rate is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b381d7fdcf6b275501061e76a4e60ec
https://pubmed.ncbi.nlm.nih.gov/35143563
https://pubmed.ncbi.nlm.nih.gov/35143563
Autor:
Huai-Ning Chang, Pascale R Leroueil, Katherine Selwa, C J Gasper, Ryan E Tsuchida, Jason J Wang, Walker M McHugh, Timothy T Cornell, James R Baker, Sascha N Goonewardena
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81889 (2013)
Rapid profiling of signaling pathways has been a long sought after goal in biological sciences and clinical medicine. To understand these signaling pathways, their protein components must be profiled. The protein components of signaling pathways are
Externí odkaz:
https://doaj.org/article/be7941900b654783804f80ec3176e1df
Publikováno v:
Bioconjugate Chemistry. 28:1649-1657
Multivalent interactions involve the engagement of multiple ligand-receptor pairs and are important in synthetic biology as design paradigms for targeted nanoparticles (NPs). However, little is known about the specific ligand parameters important to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27686a06d9c7ff5479efc28564d6467
https://doi.org/10.1021/acs.bioconjchem.7b00098
https://doi.org/10.1021/acs.bioconjchem.7b00098
Publikováno v:
ChemPlusChem. 78:430-437
Nanoparticle technologies have tremendous potential in clinical medicine. To fully realize this potential, one must further understand how nanoparticles interact with biological systems. Typically, reporters that are conjugated to nanoparticles durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ca07ddf0ab4d48ebb1009c43d531c8
https://doi.org/10.1002/cplu.201300007
https://doi.org/10.1002/cplu.201300007
Autor:
Pawan Tahiliani, Sascha N. Goonewardena, Colleen Gemborys, James R. Baker, Hong Zong, Pascale R. Leroueil, S. Emery
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2230-2233
The application of small molecule fluorescent reporters to monitor biological systems is limited by their poor water solubility and background fluorescence of these reporters. Herein, we describe the synthesis and testing of a fluorogenic 'click' den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc7b5a551405fe797ac063293394c26
https://doi.org/10.1016/j.bmcl.2013.01.061
https://doi.org/10.1016/j.bmcl.2013.01.061
Autor:
Pascale R. Leroueil, Yuehua Zhang, Jeremy J. Gam, James R. Baker, Kyung Hoon Lee, Alina Kotlyar, Hong Zong, Thommey P. Thomas, Ming Hsin Li, Mark M. Banaszak Holl, Ankur Desai
Publikováno v:
Biomacromolecules. 13:982-991
Our group previously developed a multifunctional, targeted cancer therapeutic based on Generation 5 (G5) polyamidoamine (PAMAM) dendrimers. In those studies we conjugated the targeting molecule folic acid (FA) and the chemotherapeutic drug methotrexa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f31747bd040409ffffa390eb417f7a6
https://doi.org/10.1021/bm201639c
https://doi.org/10.1021/bm201639c