Výsledky vyhledávání - "Pascale Lepelley"

Clinical significance of abcb1 in acute myeloid leukemia:a comprehensive study

Autor: Hervé Dombret, Christophe Roumier, Stéphane de Botton, Céline Berthon, Claude Preudhomme, Thomas Boyer, Adriana Plesa, Carole Delattre, Nicolas Pottier, Pauline Peyrouze, Alice Marceau-Renaut, Marc Wetterwald, Pascale Lepelley, Fanny Gonzales, Olivier Nibourel, Adeline Barthelemy, Isabelle Plantier, Soizic Guihard, Meyling Cheok

Publikováno v: Cancers
Cancers, 2019, Cancers, 11 (9), pp.1323. ⟨10.3390/cancers11091323⟩
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1323 (2019)

ABCB1 is a member of the ATP binding cassette transporter family and high ABCB1 activity is considered as a poor prognostic factor in acute myeloid leukemia (AML) treated with intensive chemotherapy, its direct relation with drug resistance remains u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e8639a7320e671eed4d06a572b78fb
http://hdl.handle.net/20.500.12210/59722

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Prognostic value of multicenter flow cytometry harmonized assessment of minimal residual disease in acute myeloblastic leukemia

Publikováno v: Hematological Oncology
Hematological Oncology, Wiley, 2018, 36 (2), pp.422-428. ⟨10.1002/hon.2488⟩

IF 3.118; International audience; The assessment of minimal residual disease (MRD) in acute myeloblastic leukemia is of growing interest as a prognostic marker of patients' outcome. Multiparameter flow cytometry (MFC), tracking leukemia-associated im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4428989aef5089bb33ce304e1b1f091a
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01698460

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Involvement of a common progenitor cell in core binding factor acute myeloid leukaemia associated with mastocytosis

Autor: Aline Renneville, Florent Dumezy, Bruno Quesnel, Nathalie Jouy, Brigitte Nelken, Christophe Roumier, Nathalie Philippe, Claude Preudhomme, Pascale Lepelley, Edouard Cornet, Céline Berthon

Publikováno v: Leukemia Research. 36:1330-1333

In core binding factor (CBF) acute myeloid leukaemia (AML), realtime quantitative PCR is useful to quantify the fusion transcript ratio (CBFβ-MYH11 and AML1-ETO, in case of inv(16) and t(8;21) respectively) in peripheral blood and bone marrow during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d8d6a676c0b2d139df069220f7f5e8
https://doi.org/10.1016/j.leukres.2012.07.001

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Macroglobulinémie de Waldenström

Autor: S. Balkaran, Pierre Morel, Christophe Roumier, José Ramón Coz Fernández, Pascale Lepelley, Julien Rossignol, Jean-Luc Laï, M. Wemeau, V. Soenen, Xavier Leleu, S. Poulain, A. Daudignon, B. Hivert, A. Hautecoeur

Publikováno v: La Revue de Médecine Interne. 31:385-394

Waldenstrom's macroglobulinemia (WM) is a B-cell disorder characterized primarily by bone marrow infiltration with lymphoplasmacytic cells, along with the presence of an IgM monoclonal gammopathy in the blood. WM remains incurable with a median of 8-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::788d33a3101e6274fffb95a570d9875c
https://doi.org/10.1016/j.revmed.2009.07.016

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Total peroxidase deficiency in eosinophils: A report on twin sisters, one with a refractory anaemia

Autor: A. Cosson, Marc Zandecki, Pierre Fenaux, Pascale Lepelley, M.H. Estienne, G. Torpier, S. Paquet, B. Lerche

Publikováno v: European Journal of Haematology. 39:77-81

A total lack of EPO was fortuitously discovered in a 63-yr-old woman from the north of France who had primary refractory anaemia, but without dysgranulopoiesis; MPO activity was normal. Her twin sister, whose blood count was normal, also had EPO defi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9c34e276e7e97f88b4e9173972cde5
https://doi.org/10.1111/j.1600-0609.1987.tb00169.x

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Prognostic significance of p16INK4a immunocytochemistry in adult ALL with standard risk karyotype

Autor: Emmanuel Gyan, Pascale Lepelley, Bruno Quesnel, Valérie Soenen, Pierre Fenaux, Jean-Luc Laï, Claude Preudhomme, Francis Bauters

Publikováno v: ResearcherID

The p16INK4a gene is frequently inactivated in acute lymphoblastic leukemia (ALL), by homozygous deletion. However, p16INK4a protein expression also varies widely in ALL blasts. We investigated the p16INK4a protein expression by immunocytochemistry (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfe185c6a448b720f399d770680d09e
https://doi.org/10.1038/sj.leu.2402153

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Expression of the multidrug resistance-associated protein in myelodysplastic syndromes

Autor: Stéphanie Poulain, Claude Preudhomme, Pierre Fenaux, Jérôme Cornillon, Nathalie Cambier, Eric Wattel, Pascale Lepelley, A. Cosson

Publikováno v: British Journal of Haematology. 110:591-598

In the myelodysplastic syndromes (MDS), P-glycoprotein (P-gp) expression is clinically associated with drug resistance, whereas the clinical significance of multidrug resistance-associated protein (MRP1) is uncertain. Bone marrow from 56 patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae237b122b6bbe207b83bc1639aa7c7d
https://doi.org/10.1046/j.1365-2141.2000.02247.x

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