Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Pascale Lause"'
Autor:
Isabelle S. Massart, Axell‐Natalie Kouakou, Nathan Pelet, Pascale Lause, Olivier Schakman, Audrey Loumaye, Michel Abou‐Samra, Louise Deldicque, Laure B. Bindels, Sonia M. Brichard, Jean‐Paul Thissen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 919-933 (2024)
Abstract Background Cancer cachexia is a life‐threatening, inflammation‐driven wasting syndrome that remains untreatable. Adiponectin, the most abundant adipokine, plays an important role in several metabolic processes as well as in inflammation
Externí odkaz:
https://doaj.org/article/0b9792a33b6040ba97dde84ba7b5169d
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Skeletal muscle, the most abundant tissue in the body, plays vital roles in locomotion and metabolism. Understanding the cellular processes that govern regulation of muscle mass and function represents an essential step in the development of therapeu
Externí odkaz:
https://doaj.org/article/fa014cd56d9e414fb53bb8b6823c08f4
Autor:
Marine Gueugneau, Donatienne d'Hose, Caroline Barbé, Marie deBarsy, Pascale Lause, Dominique Maiter, Laure B. Bindels, Nathalie M. Delzenne, Laurent Schaeffer, Yann‐Gaël Gangloff, Christophe Chambon, Cécile Coudy‐Gandilhon, Daniel Béchet, Jean‐Paul Thissen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 5, Pp 929-946 (2018)
Abstract Background Glucocorticoids (GC) play a major role in muscle atrophy. As skeletal muscle is a secretory organ, characterization of the muscle secretome elicited by muscle atrophy should allow to better understand the cellular mechanisms and t
Externí odkaz:
https://doaj.org/article/4a3965bb414142d984364415ff73edb7
Autor:
Audrey Loumaye, Pascale Lause, Xiaoling Zhong, Teresa A. Zimmers, Laure B. Bindels, Jean-Paul Thissen
Publikováno v:
Cells, Vol 11, Iss 7, p 1119 (2022)
Activin A (ActA) is considered to play a major role in cancer-induced cachexia (CC). Indeed, circulating ActA levels are elevated and predict survival in patients with CC. However, the mechanisms by which ActA mediates CC development and in particula
Externí odkaz:
https://doaj.org/article/b9da34f064e0452fb7c4e78be97886dc
Autor:
Isabelle S. Massart, Geneviève Paulissen, Audrey Loumaye, Pascale Lause, Sarah A. Pötgens, Morgane M. Thibaut, Estelle Balan, Louise Deldicque, Azeddine Atfi, Edouard Louis, Damien Gruson, Laure B. Bindels, Marie-Alice Meuwis, Jean-Paul Thissen
Publikováno v:
Cancers, Vol 12, Iss 11, p 3221 (2020)
Loss of skeletal muscle mass in cancer cachexia is recognized as a predictor of mortality. This study aimed to characterize the changes in the muscle secretome associated with cancer cachexia to gain a better understanding of the mechanisms involved
Externí odkaz:
https://doaj.org/article/488238ed90824a45973bf8d02fbc0c0d
Autor:
Sevval Nur Bilgic, Aylin Domaniku, Batu Toledo, Samet Agca, Bahar Z. C. Weber, Dilsad H. Arabaci, Zeynep Ozornek, Pascale Lause, Jean-Paul Thissen, Audrey Loumaye, Serkan Kir
SummarySkeletal muscle atrophy is a hallmark of the cachexia syndrome that is associated with poor survival and reduced quality of life in cancer patients1. Muscle atrophy involves excessive protein catabolism and loss of muscle mass and strength2. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1bb65d1df7b203e6888336a9e2b7ae6
https://doi.org/10.1101/2023.01.23.525138
https://doi.org/10.1101/2023.01.23.525138
Autor:
Sevval Nur Bilgic, Aylin Domaniku, Batu Toledo, Samet Agca, Bahar Z. C. Weber, Dilsad H. Arabaci, Zeynep Ozornek, Pascale Lause, Jean-Paul Thissen, Audrey Loumaye, Serkan Kir
Publikováno v:
Nature, Vol. 617, no. 7962, p. 827-834 (2023)
Skeletal muscle atrophy is a hallmark of the cachexia syndrome that is associated with poor survival and reduced quality of life in patients with cancer. Muscle atrophy involves excessive protein catabolism and loss of muscle mass and strength. An ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94866902808b779fc04a2d13ba973dc
https://hdl.handle.net/2078.1/276654
https://hdl.handle.net/2078.1/276654
Publikováno v:
Frontiers in physiology, Vol. 12, p. 677746 [1-13] (2021)
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Skeletal muscle, the most abundant tissue in the body, plays vital roles in locomotion and metabolism. Understanding the cellular processes that govern regulation of muscle mass and function represents an essential step in the development of therapeu
Autor:
Louise Deldicque, Morgane M. Thibaut, Damien Gruson, Pascale Lause, Edouard Louis, Audrey Loumaye, Sarah A. Pötgens, Geneviève Paulissen, Azeddine Atfi, Laure B. Bindels, Marie-Alice Meuwis, Isabelle S Massart, Jean-Paul Thissen, Estelle Balan
Publikováno v:
Cancers
Volume 12
Issue 11
Cancers, Vol. 12, no.11, p. 3221 [1-24] (2020)
Cancers, Vol 12, Iss 3221, p 3221 (2020)
Volume 12
Issue 11
Cancers, Vol. 12, no.11, p. 3221 [1-24] (2020)
Cancers, Vol 12, Iss 3221, p 3221 (2020)
Simple Summary Muscle wasting during cancer is recognized as an independent predictor of mortality. The aim of this study was to characterize the changes in the muscle secretome associated with cancer cachexia to gain a better understanding of the me
Autor:
Dominique Maiter, Donatienne d'Hose, Yann-Gaël Gangloff, Laure B. Bindels, Caroline Barbé, Laurent Schaeffer, Christophe Chambon, Marine Gueugneau, Nathalie M. Delzenne, Daniel Béchet, Cécile Coudy-Gandilhon, Pascale Lause, Marie de Barsy, Jean-Paul Thissen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 9:929-946
BACKGROUND: Glucocorticoids (GC) play a major role in muscle atrophy. As skeletal muscle is a secretory organ, characterization of the muscle secretome elicited by muscle atrophy should allow to better understand the cellular mechanisms and to identi