Výsledky vyhledávání - "Pascale Galea"

Akademický článek

Identification of a Novel Serum Proteomic Signature for Primary Sjögren’s Syndrome

Autor: Guillaume Padern, Claire Duflos, Rosanna Ferreira, Said Assou, Philippe Guilpain, Alexandre Thibault Jacques Maria, Radjiv Goulabchand, Pascale Galea, Maja Jurtela, Christian Jorgensen, Yves-Marie Pers

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

ContextPrimary Sjögren’s syndrome (pSS) is a complex heterogeneous autoimmune disease (AID) which can mimic rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). Our exploratory study investigated serum biomarkers that may discriminate

Externí odkaz: https://doaj.org/article/758193daf5864320aafda1014b4d6505

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Combining culture and microbead-based immunoassay for the early and generic detection of bacteria in platelet concentrates

Autor: Jeannette Fareh, Typhaine Dagland, Ludivine Vossier, Stéphanie Roche, Agnès Pouzet, Fanny Leon, Carole Farre, Christine Favier, Laetitia Rubrecht, Chantal Fournier-Wirth, Stéphane Rihet, Carole Chaix, Romaric Bonnet, Nicole Jaffrezic-Renault, Lionel Valera, Pascale Galea, Gaelle‐Anne Cremer, Dominique Piquer

Publikováno v: Transfusion
Transfusion, Wiley, 2019, 59 (1), pp.277-286. ⟨10.1111/trf.15019⟩

BACKGROUND Despite current preventive strategies, bacterial contamination of platelets is the highest residual infectious risk in transfusion. Bacteria can grow from an initial concentration of 0.03-0.3 colony-forming units (CFUs)/mL up to 108 to 109

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833e20e87a9843ce96dcccc49d2e4335
https://hal.umontpellier.fr/hal-01934702

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Circulating Osteoglycin and NGAL/MMP9 Complex Concentrations Predict 1-Year Major Adverse Cardiovascular Events After Coronary Angiography

Autor: Rohit M. Oemrawsingh, Hector M. Garcia-Garcia, K. Martijn Akkerhuis, Frederic Jaisser, Robert-Jan van Geuns, Emilie du Paty, Pascale Galea, Olivier Meilhac, Jin M. Cheng, Patrick W. Serruys, Patrick Rossignol, Jeannette Fareh, Delphine Merle, Dominique Piquer, Eric Boersma, Isabella Kardys

Publikováno v: Arteriosclerosis Thrombosis & Vascular Biology, 34(5), 1078-1084. Lippincott Williams & Wilkins

Objective— Previous proteomics experiments have demonstrated that several proteins are differentially expressed in vulnerable human carotid plaques compared with stable plaques. This study aims to investigate the prognostic value of 13 such circula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba10c2e90725a9aad6b52cb8ec1f71d5
https://doi.org/10.1161/atvbaha.114.303486

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Generation and molecular characterization of a monoclonal antibody reactive with conserved epitope in sphingomyelinases D from Loxosceles spider venoms

Autor: Laurence Molina, Carlos Chávez-Olórtegui, Sandra Cobo, Laetitia Rubrecht, Claude Granier, F. Molina, Camila Dias-Lopes, Christophe Nguyen, Pascale Galea, Liza Felicori

Publikováno v: Vaccine
Vaccine, Elsevier, 2014, 32 (18), pp.2086-2092. ⟨10.1016/j.vaccine.2014.02.012⟩

We report the production of a neutralizing monoclonal antibody able to recognize the venoms of three major medically important species of Loxosceles spiders in Brazil. The mAb was produced by immunization of mice with a toxic recombinant L. intermedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e741637a0a830d227746b8378c9c9bf

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Local carotid atherosclerotic plaque proteins for the identification of circulating biomarkers in coronary patients

Autor: Francois Rieunier, Daniel Laune, Jeannette Fareh, Dominique Piquer, Bernard Albat, Aurélie Blanc, Eric Malaud, Olivier Meilhac, Agnès Pouzet, Charles Marty-Ané, Franck Molina, Sandra Cobo, Laetitia Rubrecht, Laurence Molina, Saussine M, Emilie Dupaty, Pascale Galea, Nicolas Salvetat, Delphine Merle

Publikováno v: Atherosclerosis
Atherosclerosis, Elsevier, 2014, 233 (2), pp.551-558. ⟨10.1016/j.atherosclerosis.2013.12.019⟩

To identify circulating biomarkers that originate from atherosclerotic vulnerable plaques and that could predict future cardiovascular events.After a protein enrichment step (combinatorial peptide ligand library approach), we performed a two-dimensio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14745868fc458e7cfe0f8470d48a959
https://doi.org/10.1016/j.atherosclerosis.2013.12.019

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Development of monoclonal antibodies to pre-haptoglobin 2 and their use in an enzyme-linked immunosorbent assay (ELISA)

Autor: F. Rieunier, E. Du Paty, Michelle Delanoy, Roger P. Walker, Daniel Laune, Steven R. Binder, John J. Flanagan, Pascale Galea, Audrey Arjomandi

Publikováno v: Journal of immunological methods. 406

Haptoglobins (HPs) are alpha 2-globulin proteins that bind free hemoglobin in plasma to prevent oxidative damage. HPs are produced as preproteins that are proteolytically cleaved in the ER into alpha and beta chains prior to forming mature, functiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633573438f59fca8b811d3b38bcb0d90
https://pubmed.ncbi.nlm.nih.gov/24583194

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A novel epitope R7V common to all HIV-1 isolates is recognized by neutralizing IgG found in HIV-infected patients and immunized rabbits

Autor: C. Le Contel, Pascale Galea, Jean-Claude Chermann

Publikováno v: Vaccine. 17:1454-1461

We have previously reported that the presence of antibodies (Ab) directed to the β2-microglobulin-derived peptide R7V in patient's serum correlated with the nonprogression to AIDS. In order to investigate whether R7V motif could represent a potentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbd930d6c064039e7b0cc42b980126c
https://doi.org/10.1016/s0264-410x(98)00374-0

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New Bicyclam−AZT Conjugates: Design, Synthesis, Anti-HIV Evaluation, and Their Interaction with CXCR-4 Coreceptor

Autor: Patrick Vlieghe, Jean-Louis Kraus, Jean Dessolin, Jean-Claude Chermann, Pascale Galea

Publikováno v: Journal of Medicinal Chemistry. 42:229-241

We report the synthesis of mono- and bis-tetraazamacrocycle-AZT conjugates. All new compounds were screened for their ability to inhibit HIV-1 replication in MT4 cell line and were compared to AZT alone. It appears that N-protected covalent prodrugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067a586e91114221712e1e44e5a1f912
https://doi.org/10.1021/jm980358u

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[Untitled]

Autor: Pascale Galea, Jean-Claude Chermann

Publikováno v: Genetica. 104:133-142

This brief article is in response to the previous article by Peter Duesberg and David Rasnick titled 'The AIDS Dilemma: Drug Diseases Blamed on a Passenger Virus.' We focus our response on thirteen specific issues raised by Duesberg and Rasnick.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5872acd49acb31986d5aa4cf9bd32b0
https://doi.org/10.1023/a:1003432603348

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