Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pascale F, Macgregor"'
Autor:
Marcus Bernardini, Chung-Hae Lee, Ben Beheshti, Mona Prasad, Monique Albert, Paula Marrano, Heather Begley, Patricia Shaw, Al Covens, Joan Murphy, Barry Rosen, Salomon Minkin, Jeremy A. Squire, Pascale F. Macgregor
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 6, Pp 603-613 (2005)
Array comparative genomic hybridization (aCGH) and microarray expression profiling were used to subclassify DNA and RNA alterations associated with differential response to chemotherapy in ovarian cancer. Two to 4 Mb interval arrays were used to map
Externí odkaz:
https://doaj.org/article/f483f6995b4c45538a85c573a4e42b4f
Autor:
Nathalie Wong, Kathy Y-Y. Chan, Pascale F. Macgregor, Paul B-S. Lai, Jeremy A. Squire, Ben Beheshti, Monique Albert, Thomas W-T. Leung
Publikováno v:
Clinical Cancer Research. 11:1319-1326
Purpose: Treatment with IFN-α therapy has been shown to exhibit antitumor effects on patients with hepatocellular carcinoma (HCC). However, individual responses remained unpredictable because of the frequent presence of intrinsic or acquired IFN-α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::453e8d4dcb41857b1de4cbb3ba82a129
https://doi.org/10.1158/1078-0432.1319.11.3
https://doi.org/10.1158/1078-0432.1319.11.3
Autor:
Pascale F. Macgregor, Chung-Hae Lee
Publikováno v:
Pharmacogenomics. 5:611-625
Chemotherapy resistance remains a major obstacle to successful treatment and better outcome in cancer patients. The advent of whole genome experimental strategies, such as DNA microarrays, has transformed the way researchers approach cancer research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a3b8098ea63b2e0bc07e4492834098
https://doi.org/10.1517/14622416.5.6.611
https://doi.org/10.1517/14622416.5.6.611
Autor:
Jin Sun, Peter T. Kim, Limin Chen, Pascale F. Macgregor, Qiongfang Cao, Aled M. Edwards, M. James Phillips, Katryn N. Furuya, Andrew B. Goryachev, Hui Zhang, Sylvie Lebel
Publikováno v:
Hepatology. 38:567-576
Biliary atresia (BA) is characterized by a progressive, sclerosing, inflammatory process that leads to cirrhosis in infancy. Although it is the most common indication for liver transplantation in early childhood, little is known about its etiopathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d7a0b29225e0a24f016e86d1e7b806
https://doi.org/10.1053/jhep.2003.50363
https://doi.org/10.1053/jhep.2003.50363
Autor:
Jeremy A. Squire, Pascale F. Macgregor
Publikováno v:
Clinical Chemistry. 48:1170-1177
Molecular diagnostics is a rapidly advancing field in which insights into disease mechanisms are being elucidated by use of new gene-based biomarkers. Until recently, diagnostic and prognostic assessment of diseased tissues and tumors relied heavily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42270fd7c628fd5106a5a6381a7396e3
https://doi.org/10.1093/clinchem/48.8.1170
https://doi.org/10.1093/clinchem/48.8.1170
Publikováno v:
Journal of Computational Biology. 8:443-461
The use of DNA microarrays for the analysis of complex biological samples is becoming a mainstream part of biomedical research. One of the most commonly used methods compares the relative abundance of mRNA in two different samples by probing a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486d924d667701bda428baf5e0617d84
https://doi.org/10.1089/106652701752236232
https://doi.org/10.1089/106652701752236232
Autor:
Mona Prasad, K. Joan Murphy, Pascale F. Macgregor, Monique Albert, Dan Grisaru, Jan Hauspy, Barry P. Rosen, Allan Covens
Publikováno v:
Oncology Reports.
The lack of reliable early detection of ovarian cancer and the absence of specific symptoms result in diagnosis of ovarian cancer at advanced stage in the majority of the patients. Through gene expression profiling we can identify important genes tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07166b8078394e05553fa286b5515bcc
https://doi.org/10.3892/or.18.6.1347
https://doi.org/10.3892/or.18.6.1347
Autor:
Monique Albert, Ying Hu, Paul B.S. Lai, Elizabeth Pang, Kathy Yuen Yee Chan, Pascale F. Macgregor, Jeremy A. Squire, Ben Beheshti, Thomas W.T. Leung, Nathalie Wong
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 85(5)
Administration of doxorubicin has been shown to prolong survival of patients with hepatocellular carcinoma (HCC). However, treatment regimen is often complicated by the emergence of drug resistance. The goal of our study is to enhance our understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6ac4bc9f24db6b4483a4b50ab82b8b
https://pubmed.ncbi.nlm.nih.gov/15765123
https://pubmed.ncbi.nlm.nih.gov/15765123
Autor:
Nathalie, Wong, Kathy Y-Y, Chan, Pascale F, Macgregor, Paul B-S, Lai, Jeremy A, Squire, Ben, Beheshti, Monique, Albert, Thomas W-T, Leung
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(3)
Treatment with IFN-alpha therapy has been shown to exhibit antitumor effects on patients with hepatocellular carcinoma (HCC). However, individual responses remained unpredictable because of the frequent presence of intrinsic or acquired IFN-alpha res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01d3bc05f984ce0a75d3ce0d4e48a251
https://pubmed.ncbi.nlm.nih.gov/15709204
https://pubmed.ncbi.nlm.nih.gov/15709204
Autor:
Nathalie Wong, Ka Fai To, Philip J. Johnson, Pascale F. Macgregor, Jeremy A. Squire, Paul B.S. Lai, Kathy Yuen Yee Chan, Monique Albert, Ben Beheshti
Publikováno v:
International journal of cancer. 114(6)
Chromosomal rearrangements unraveled by spectral karyotyping (SKY) indicated frequent chromosome 19 translocations in hepatocellular carcinoma (HCC). In an effort to characterize the aberrant 19 rearrangements in HCC, we performed positional mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400b60e4617e94c9820720e11d03d617
https://pubmed.ncbi.nlm.nih.gov/15645427
https://pubmed.ncbi.nlm.nih.gov/15645427