Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pascale Duplay"'
Publikováno v:
Virology. 511:66-73
Previous studies have shown that HSV-1 infection of lymphocytes induces the tyrosine phosphorylation of several proteins that might correspond to viral or host proteins. VP11/12, a viral tegument protein, is the major HSV-induced tyrosine phosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd433b70d854572f26f758c9c90b3ba
https://doi.org/10.1016/j.virol.2017.08.018
https://doi.org/10.1016/j.virol.2017.08.018
Publikováno v:
Microbes and Infection. 17:285-294
Three adaptor molecules of the Dok family, Dok-1, Dok-2 and Dok-3 are expressed in macrophages and are involved in the negative regulation of signaling in response to lipopolysaccharide and various cytokines and growth factors. We investigated the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1ff96f18ed453862c32ed3b5104277
https://doi.org/10.1016/j.micinf.2014.12.011
https://doi.org/10.1016/j.micinf.2014.12.011
Publikováno v:
Journal of Virology. 91
Dok-1 and Dok-2 negatively regulate responses downstream of several immune receptors in lymphoid and myeloid cells. Recent evidence showed that Dok proteins are essential in the formation of memory CD8 + T cells to an exogenous epitope expressed by v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88e715b9ad4a8f49c371e7ac4bc8ecb
https://doi.org/10.1128/jvi.02297-16
https://doi.org/10.1128/jvi.02297-16
Publikováno v:
Journal of virology. 91(15)
Dok-1 and Dok-2 negatively regulate responses downstream of several immune receptors in lymphoid and myeloid cells. Recent evidence showed that Dok proteins are essential in the formation of memory CD8+ T cells to an exogenous epitope expressed by va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93c11cc1cb4971162d55783d959c90df
https://pubmed.ncbi.nlm.nih.gov/28490594
https://pubmed.ncbi.nlm.nih.gov/28490594
Publikováno v:
The Journal of Experimental Medicine
p56lck, a member of the src family of protein tyrosine kinases, is an essential component in T cell receptor (TCR) signal transduction. p56lck contains a src homology 2 (SH2) domain found in a number of proteins involved in intracellular signaling. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079f7c371483ac096a0e509a10a083e0
https://doi.org/10.1084/jem.179.4.1163
https://doi.org/10.1084/jem.179.4.1163
Autor:
Pascale Duplay, Tania Charpentier, Mitra Yousefi, Simona Stäger, Jean-François Daudelin, Roscoe Klinck, Esther Tarrab, Alain Lamarre, Constance Laroche-Lefebvre, Nathalie Labrecque
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2017, 197 (9), pp.3618-3627. ⟨10.4049/jimmunol.1600385⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2017, 197 (9), pp.3618-3627. ⟨10.4049/jimmunol.1600385⟩
Diverse signals received by CD8+ T cells are integrated to achieve the required magnitude of cell expansion and the appropriate balance of effector/memory CD8+ T cell generation. Notably, the strength and nature of TCR signaling influence the differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38787ab7898b08df307625c81d7fa931
https://pubmed.ncbi.nlm.nih.gov/27664281
https://pubmed.ncbi.nlm.nih.gov/27664281
Publikováno v:
European Journal of Immunology. 42:2491-2504
In T cells, two members of the Dok family, Dok-1 and Dok-2, are predominantly expressed. Recent evidence suggests that they play a negative role in T-cell signaling. In order to define whether Dok proteins regulate T-cell development, we have generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437760b76fd3ffbe23bf276862ba8a15
https://doi.org/10.1002/eji.201242421
https://doi.org/10.1002/eji.201242421
Autor:
Fabien Garçon, Audrey Gérard, Yves Collette, Sonia Pastor, Cédric Favre, Jacques A. Nunès, Daniel Olive, Jean-Guy Némorin, Pascale Duplay
Publikováno v:
Oncogene. 23:1594-1598
The Dok adaptor family of proteins binding to RasGAP, consisting of Dok-1 and Dok-2, are critical regulators in cell proliferation. These molecules are partners and/or substrates of different protein tyrosine kinases considered as oncoproteins. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0d443c6bb6304f9654b86a9e9b1699
https://doi.org/10.1038/sj.onc.1207283
https://doi.org/10.1038/sj.onc.1207283
Autor:
Pascale Duplay, Rashmi Kothary, John R. Webb, Ahmed Zafer, Philippe Gros, Michel L. Tremblay, Yves De Repentigny, Seung-Hwan Lee, Silvia M. Vidal
Publikováno v:
The Journal of Experimental Medicine
Natural resistance to infection with mouse cytomegalovirus (MCMV) is controlled by a dominant locus, Cmv1. Cmv1 is linked to the Ly49 family of natural killer receptors on distal chromosome 6. While some studies localized Cmv1 as distal to the Ly49 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1931e3827accc1912033b70e3d2b8a
https://doi.org/10.1084/jem.20021713
https://doi.org/10.1084/jem.20021713
Publikováno v:
The Journal of Immunology. 166:4408-4415
p62dok belongs to a newly identified family of adaptor proteins. In T cells, the two members that are predominantly expressed, p56dok and p62dok, are tyrosine phosphorylated upon CD2 or CD28 stimulation, but not upon CD3 ligation. Little is known abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212ff560a03464788da7e51564d2e1b1
https://doi.org/10.4049/jimmunol.166.7.4408
https://doi.org/10.4049/jimmunol.166.7.4408