Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Pascale Coric"'
Autor:
Elodie Bosc, Julie Anastasie, Feryel Soualmia, Pascale Coric, Ju Youn Kim, Lily Q. Wang, Gullen Lacin, Kaitao Zhao, Ronak Patel, Eric Duplus, Philippe Tixador, Andrew A. Sproul, Bernard Brugg, Michelle Reboud-Ravaux, Carol M. Troy, Michael L. Shelanski, Serge Bouaziz, Michael Karin, Chahrazade El Amri, Etienne D. Jacotot
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract Caspase-2 (Casp2) is a promising therapeutic target in several human diseases, including nonalcoholic steatohepatitis (NASH) and Alzheimer’s disease (AD). However, the design of an active-site-directed inhibitor selective to individual cas
Externí odkaz:
https://doaj.org/article/e2ca2ef1c4d34003bb95c448c8eb4433
Autor:
Guillaume Le Guyader, Bernard Do, Ivo B. Rietveld, Pascale Coric, Serge Bouaziz, Jean-Michel Guigner, Philippe-Henri Secretan, Karine Andrieux, Muriel Paul
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 569 (2022)
Facial angiofibromas (FA) are one of the most obvious cutaneous manifestations of tuberous sclerosis complex. Topical rapamycin for angiofibromas has been reported as a promising treatment. Several types of vehicles have been used hitherto, but polym
Externí odkaz:
https://doaj.org/article/51227dd701c843f8b047dc46ce9e5319
Autor:
Jean-François Gaucher, Marie Reille-Seroussi, Nathalie Gagey-Eilstein, Sylvain Broussy, Pascale Coric, Bili Seijo, Marie-Bernard Lascombe, Benoit Gautier, Wang-Quing Liu, Florent Huguenot, Nicolas Inguimbert, Serge Bouaziz, Michel Vidal, Isabelle Broutin
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167755 (2016)
Angiogenesis is tightly regulated through the binding of vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs). In this context, we showed that human VEGFR1 domain 2 crystallizes in the presence of Zn2+, Co2+ or Cu2+ as a dimer that
Externí odkaz:
https://doaj.org/article/945d9e856baa4145be209985052c44c6
Autor:
Gaëlle Gonzalez, Sandrina DaFonseca, Elisabeth Errazuriz, Pascale Coric, Florence Souquet, Serge Turcaud, Pierre Boulanger, Serge Bouaziz, Saw See Hong
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27234 (2011)
The HIV-1 auxiliary protein Vpr and Vpr-fusion proteins can be copackaged with Gag precursor (Pr55Gag) into virions or membrane-enveloped virus-like particles (VLP). Taking advantage of this property, we developed a simple and sensitive method to eva
Externí odkaz:
https://doaj.org/article/3cd2480a46d64552b560e821c1be7403
Publikováno v:
Biomolecular NMR Assignments
Biomolecular NMR Assignments, Springer, 2021, 15 (2), pp.267-271. ⟨10.1007/s12104-021-10016-9⟩
Biomolecular NMR Assignments, Springer, 2021, 15 (2), pp.267-271. ⟨10.1007/s12104-021-10016-9⟩
During the maturation of the HIV-1 particle, the Gag polyprotein is cleaved by the viral protease into several proteins: matrix (MA), capsid (CA), spacer peptide 1 (SP1), nucleocapsid (NC), spacer peptide 2 (SP2) and p6. After cleavage, these protein
Autor:
Xiaowei Chen, Xiao Wang, Serge Bouaziz, Sylvie Nonin-Lecomte, Serge Turcaud, Pascale Coric, Valery Larue
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 204, pp.112634. ⟨10.1016/j.ejmech.2020.112634⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 204, pp.112634. ⟨10.1016/j.ejmech.2020.112634⟩
International audience; During the maturation of HIV-1 particle, the Gag polyprotein is cleaved into several proteins by the HIV-1 protease. These proteins rearrange to form infectious virus particles. In this study, the solution structure and dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dffacc0c75b8c05fc28f5bf93dbdfd8
https://hal.archives-ouvertes.fr/hal-02914317
https://hal.archives-ouvertes.fr/hal-02914317
Autor:
Sandrina Dafonseca, Armand Blommaert, Pascale CORIC, Saw See Hong, Serge Bouaziz, Pierre Boulanger
Publikováno v:
Antiviral Therapy
Antiviral Therapy, International Medical Press, 2019, 12 (8), pp.1185-203
Antiviral Therapy, 2019, 12 (8), pp.1185-203
HAL
Antiviral Therapy, International Medical Press, 2019, 12 (8), pp.1185-203
Antiviral Therapy, 2019, 12 (8), pp.1185-203
HAL
The 3-O-(3',3'-dimethylsuccinyl) derivative of betulinic acid (DSB) blocks HIV-1 maturation by interfering with viral protease (PR) at the capsid (CA)-SP1 cleavage site, a crucial region in HIV-1 morphogenesis.We analysed the effect of DSB on the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0060aefcd1ca5c00d6c8f8e8dcabb3c4
https://hal.archives-ouvertes.fr/hal-02122515
https://hal.archives-ouvertes.fr/hal-02122515
Insight into the mechanism of action of EP-39, a bevirimat derivative that inhibits HIV-1 maturation
Autor:
Aymeric Neyret, Bernard Gay, Anaïs Cransac, Laurence Briant, Pascale Coric, Serge Turcaud, Philippe Laugâa, Serge Bouaziz, Nathalie Chazal
Publikováno v:
Antiviral Research
Antiviral Research, Elsevier Masson, 2019, 164, pp.162-175. ⟨10.1016/j.antiviral.2019.02.014⟩
Antiviral Research, 2019, 164, pp.162-175. ⟨10.1016/j.antiviral.2019.02.014⟩
Antiviral Research, Elsevier Masson, 2019, 164, pp.162-175. ⟨10.1016/j.antiviral.2019.02.014⟩
Antiviral Research, 2019, 164, pp.162-175. ⟨10.1016/j.antiviral.2019.02.014⟩
International audience; Maturation of human immunodeficiency virus type 1 (HIV-1) particles is a key step for viral infectivity. This process can be blocked using maturation inhibitors (MIs) that affect the cleavage of the capsid-spacer peptide 1 (CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc5ed1c5e94c5c23aebd0b7c278b620
https://hal.archives-ouvertes.fr/hal-02147099/file/1-s2.0-S0166354218307162-main(1).pdf
https://hal.archives-ouvertes.fr/hal-02147099/file/1-s2.0-S0166354218307162-main(1).pdf
Publikováno v:
Journal of Cellular Physiology
Journal of Cellular Physiology, Wiley, 2018, 234 (6), pp.8295-8315. ⟨10.1002/jcp.27715⟩
Journal of Cellular Physiology, 2018, 234 (6), pp.8295-8315. ⟨10.1002/jcp.27715⟩
J Cell Physiol
Journal of Cellular Physiology, Wiley, 2018, 234 (6), pp.8295-8315. ⟨10.1002/jcp.27715⟩
Journal of Cellular Physiology, 2018, 234 (6), pp.8295-8315. ⟨10.1002/jcp.27715⟩
J Cell Physiol
International audience; Polyomavirus family consists of a highly diverse group of small DNA viruses. The founding family member (MPyV) was first discovered in the newborn mouse in the late 1950s, which induces solid tumors in a wide variety of tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac3249f73114a697134f24096975827
https://hal.archives-ouvertes.fr/hal-02122318
https://hal.archives-ouvertes.fr/hal-02122318
Autor:
Serge Bouaziz, A. Sami Saribas, William E. Davis, Jon H. Condra, Mahmut Safak, Pascale Coric, Wayne E. Childers, Magid Abou-Gharbia, Rachael Axman, Anahit Hamazaspyan, Martyn K. White
Publikováno v:
Journal of Cellular Physiology. 231:2115-2127
Agnoprotein is an important regulatory protein of polyomaviruses, including JCV, BKV, and SV40. In the absence of its expression, these viruses are unable to sustain their productive life cycle. It is a highly basic phosphoprotein that localizes most