Výsledky vyhledávání

Akademický článek

Population pharmacokinetics of intraperitoneal irinotecan and SN‐38 in patients with peritoneal metastases from colorectal origin

Autor: Pascale C. S. Rietveld, Sebastiaan D. T. Sassen, Niels A. D. Guchelaar, Ruben A. G. vanEerden, Nadine L. deBoer, Teun B. M. van denHeuvel, Jacobus W. A. Burger, Ron H. J. Mathijssen, Birgit C. P. Koch, Stijn L. W. Koolen

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 6, Pp 1006-1016 (2024)

Abstract Peritoneal metastases (PM) are common in patients with colorectal cancer. Patients with PM have a poor prognosis, and for those who are not eligible for cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (H

Externí odkaz: https://doaj.org/article/4f09a3b0d33048d7baa42ac1df72d762

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Entre la Iglesia y los jóvenes

Autor: Pascale C. Larré Vargas, Blanca Besa Bandeira, Carolina Flores Marabolí, Matías Echiburú

Publikováno v: Revista de Educación Religiosa, Vol 3, Iss 1 (2024)

Tanto en Chile como en el mundo, los grupos societarios más jóvenes han demostrado un flujo constante de cambios culturales y religiosos. Esto desafía las formas en que ellos se relacionan con las propuestas pastorales tradicionales, y si estas pu

Externí odkaz: https://doaj.org/article/d90b2d954b2c432bba4de1d824c9cbd8

Zobrazit plný text záznamu

Akademický článek

Chronic Mg2+ Deficiency Does Not Impair Insulin Secretion in Mice

Autor: Noushafarin Khajavi, Klea Riçku, Pascale C. F. Schreier, Tanja Gentz, Philipp Beyerle, Emmanuel Cruz, Andreas Breit, Peter S. Reinach, Thomas Gudermann

Publikováno v: Cells, Vol 12, Iss 13, p 1790 (2023)

Magnesium is an essential mediator of a vast number of critical enzymatic cellular reactions in the human body. Some clinical epidemiological studies suggest that hypomagnesemia accounts for declines in insulin secretion in patients with type 2 diabe

Externí odkaz: https://doaj.org/article/1a0ea34db118460cbd75b1d806b530a7

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

A combined microphysiological-computational omics approach in dietary protein evaluation

Autor: Paulus G. M. Jochems, Willem R. Keusters, Antoine H. P. America, Pascale C. S. Rietveld, Shanna Bastiaan-Net, Renata M. C. Ariëns, Monic M. M. Tomassen, Fraser Lewis, Yang Li, Koen G. C. Westphal, Johan Garssen, Harry J. Wichers, Jeroen van Bergenhenegouwen, Rosalinde Masereeuw

Publikováno v: npj Science of Food, Vol 4, Iss 1, Pp 1-9 (2020)

Abstract Food security is under increased pressure due to the ever-growing world population. To tackle this, alternative protein sources need to be evaluated for nutritional value, which requires information on digesta peptide composition in comparis

Externí odkaz: https://doaj.org/article/8b3824adfd8543ed9a5b564af4ad6739

Zobrazit plný text záznamu

Akademický článek

Novel Dietary Proteins Selectively Affect Intestinal Health In Vitro after Clostridium difficile-Secreted Toxin A Exposure

Autor: Paulus G. M. Jochems, Johan Garssen, Pascale C. S. Rietveld, Coen Govers, Monic M. M. Tomassen, Harry J. Wichers, Jeroen van Bergenhenegouwen, Rosalinde Masereeuw

Publikováno v: Nutrients, Vol 12, Iss 9, p 2782 (2020)

Bacterial gastroenteritis forms a burden on a global scale, both socially and economically. The Gram-positive bacterium Clostridium difficile is an inducer of gastrointestinal bacterial infections, often triggered following disruption of the microbio

Externí odkaz: https://doaj.org/article/966b75a133244595bee934b2e7207916

Zobrazit plný text záznamu