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Akademický článek

Population pharmacokinetics of intraperitoneal irinotecan and SN‐38 in patients with peritoneal metastases from colorectal origin

Autor: Pascale C. S. Rietveld, Sebastiaan D. T. Sassen, Niels A. D. Guchelaar, Ruben A. G. vanEerden, Nadine L. deBoer, Teun B. M. van denHeuvel, Jacobus W. A. Burger, Ron H. J. Mathijssen, Birgit C. P. Koch, Stijn L. W. Koolen

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 6, Pp 1006-1016 (2024)

Abstract Peritoneal metastases (PM) are common in patients with colorectal cancer. Patients with PM have a poor prognosis, and for those who are not eligible for cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (H

Externí odkaz: https://doaj.org/article/4f09a3b0d33048d7baa42ac1df72d762

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Akademický článek

Entre la Iglesia y los jóvenes

Autor: Pascale C. Larré Vargas, Blanca Besa Bandeira, Carolina Flores Marabolí, Matías Echiburú

Publikováno v: Revista de Educación Religiosa, Vol 3, Iss 1 (2024)

Tanto en Chile como en el mundo, los grupos societarios más jóvenes han demostrado un flujo constante de cambios culturales y religiosos. Esto desafía las formas en que ellos se relacionan con las propuestas pastorales tradicionales, y si estas pu

Externí odkaz: https://doaj.org/article/d90b2d954b2c432bba4de1d824c9cbd8

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Akademický článek

Chronic Mg2+ Deficiency Does Not Impair Insulin Secretion in Mice

Autor: Noushafarin Khajavi, Klea Riçku, Pascale C. F. Schreier, Tanja Gentz, Philipp Beyerle, Emmanuel Cruz, Andreas Breit, Peter S. Reinach, Thomas Gudermann

Publikováno v: Cells, Vol 12, Iss 13, p 1790 (2023)

Magnesium is an essential mediator of a vast number of critical enzymatic cellular reactions in the human body. Some clinical epidemiological studies suggest that hypomagnesemia accounts for declines in insulin secretion in patients with type 2 diabe

Externí odkaz: https://doaj.org/article/1a0ea34db118460cbd75b1d806b530a7

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Akademický článek

A combined microphysiological-computational omics approach in dietary protein evaluation

Autor: Paulus G. M. Jochems, Willem R. Keusters, Antoine H. P. America, Pascale C. S. Rietveld, Shanna Bastiaan-Net, Renata M. C. Ariëns, Monic M. M. Tomassen, Fraser Lewis, Yang Li, Koen G. C. Westphal, Johan Garssen, Harry J. Wichers, Jeroen van Bergenhenegouwen, Rosalinde Masereeuw

Publikováno v: npj Science of Food, Vol 4, Iss 1, Pp 1-9 (2020)

Abstract Food security is under increased pressure due to the ever-growing world population. To tackle this, alternative protein sources need to be evaluated for nutritional value, which requires information on digesta peptide composition in comparis

Externí odkaz: https://doaj.org/article/8b3824adfd8543ed9a5b564af4ad6739

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Akademický článek

An Analysis of Greek Terracotta Figurines at the Museum of Anthropology, University of British Columbia

Autor: Pascale C. Schittecatte

Publikováno v: Les Carnets de l’ACoSt, Vol 11 (2014)

Externí odkaz: https://doaj.org/article/34297442b22543db962aac4c9987ec86

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Akademický článek

Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity.

Autor: Simone A Joosten, Krista E van Meijgaarden, Pascale C van Weeren, Fatima Kazi, Annemieke Geluk, Nigel D L Savage, Jan W Drijfhout, Darren R Flower, Willem A Hanekom, Michèl R Klein, Tom H M Ottenhoff

Publikováno v: PLoS Pathogens, Vol 6, Iss 2, p e1000782 (2010)

Tuberculosis (TB) is an escalating global health problem and improved vaccines against TB are urgently needed. HLA-E restricted responses may be of interest for vaccine development since HLA-E displays very limited polymorphism (only 2 coding variant

Externí odkaz: https://doaj.org/article/7131a35e2dd241dda2087c4d374e973e

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