Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pascale Blais Lecours"'
Autor:
Olivier Courtemanche, Carole-Ann Huppé, Pascale Blais Lecours, Ophélie Lerdu, Joanny Roy, Jean-François Lauzon-Joset, Marie-Renée Blanchet, Mathieu C. Morissette, David Marsolais
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Hypersensitivity pneumonitis (HP) is an interstitial lung disease characterized by antigen-triggered neutrophilic exacerbations. Although CD4+ T cells are sufficient for HP pathogenesis, this never translated into efficient T cell
Externí odkaz:
https://doaj.org/article/fc9640caf71c49fd89d759570b473330
Autor:
Pascale Blais Lecours, David Marsolais, Yvon Cormier, Marie Berberi, Chantal Haché, Raymond Bourdages, Caroline Duchaine
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87734 (2014)
The gut microbiota is associated with the modulation of mucosal immunity and the etiology of inflammatory bowel diseases (IBD). Previous studies focused on the impact of bacterial species on IBD but seldom suspected archaea, which can be a major cons
Externí odkaz:
https://doaj.org/article/149956e5b7fe454a9a336535b720790c
Autor:
Pascale Blais Lecours, Caroline Duchaine, Michel Taillefer, Claudine Tremblay, Marc Veillette, Yvon Cormier, David Marsolais
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23326 (2011)
The etiology of bioaerosol-related pulmonary diseases remains poorly understood. Recently, archaea emerged as prominent airborne components of agricultural environments, but the consequences of airway exposure to archaea remain unknown. Since subcomp
Externí odkaz:
https://doaj.org/article/710a9092e0064f86b56f3eb486f584e6
Autor:
Steeve Provencher, François Potus, Pascale Blais-Lecours, Sarah Bernard, Sandra Martineau, Sandra Breuils-Bonnet, Jason Weatherald, Mike Sweeney, Ewelina Kulikowski, Olivier Boucherat, Sebastien Bonnet
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 205:1357-1360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed10eecdda4b79ee5b505a6ba34f2691
https://doi.org/10.1164/rccm.202109-2182le
https://doi.org/10.1164/rccm.202109-2182le
Autor:
Geneviève Dion, Caroline Duchaine, Mathieu C. Morissette, Kelly M. McNagny, Carole-Ann Huppé, Emilie Bernatchez, Hugh Rosen, Pascale Blais-Lecours, Marie-Renée Blanchet, David Marsolais, Jean-François Lauzon-Joset
Publikováno v:
Am J Respir Cell Mol Biol
In a proportion of patients with hypersensitivity pneumonitis, the biological and environmental factors that sustain inflammation are ill defined, resulting in no effective treatment option. Bioaerosols found in occupational settings are complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbab58b738fae41f5839bcd76113a1f
https://doi.org/10.1165/rcmb.2019-0339oc
https://doi.org/10.1165/rcmb.2019-0339oc
Autor:
David Marsolais, Jorge Soliz, Pascale Blais-Lecours, Vincent Joseph, Janette K. Burgess, Christian Arias-Reyes, Andrew J. Halayko, Webster L. Santos, Sofien Laouafa
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology, 62(1), 35-42. AMER THORACIC SOC
Thickening of the airway smooth muscle is central to bronchial hyperreactivity. We have shown that the sphingosine analog (R)-2-amino-4-(4-heptyloxyphenyl)-2-methylbutanol (AAL-R) can reverse preestablished airway hyperreactivity in a chronic asthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85419012de5bd3d0cdb30e815703b33
https://doi.org/10.1165/rcmb.2018-0397OC
https://doi.org/10.1165/rcmb.2018-0397OC
Autor:
Magali Boucher, Pascale Blais Lecours, Caroline Duchaine, Valérie Létourneau, Marc Veillette, David Marsolais
Publikováno v:
Toxicology in Vitro. 50:391-398
Bioaerosol exposure in highly contaminated occupational settings is associated with an increased risk of disease. Yet, few determinants allow for accurate prediction of the immunopathogenic potential of complex bioaerosols. Since dendritic cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf0166cd31caf8d18c0b75e97febf70
https://doi.org/10.1016/j.tiv.2018.04.011
https://doi.org/10.1016/j.tiv.2018.04.011
Autor:
Jacques Couet, Mathieu Laplante, Stéphanie Miard, Yohan Bossé, Pascale Blais-Lecours, Julie Lacombe, Frédéric Picard, Denis Richard, Julie S. Lefebvre, Marie Claude Drolet, Philippe St-Pierre, Sandrine Sallé-Lefort, Mathieu Ferron, Sophie Carter, Emilie Lavoie-Charland, Fernando F. Anhê, Alexandre Caron, Yves Deshaies, André Marette, David Marsolais
Publikováno v:
Diabetes. 67:1285-1296
The current demographic shift toward an aging population has led to a robust increase in the prevalence of age-associated metabolic disorders. Interestingly, recent studies have demonstrated that the etiology of obesity-related insulin resistance dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adae52003d86d8bc9b3f6474c6c62fca
https://doi.org/10.2337/db17-0558
https://doi.org/10.2337/db17-0558
Autor:
Valérie Perreault-Vallières, David Marsolais, Geneviève Dion, Anne-Marie Lemay, Ynuk Bossé, Pascale Blais Lecours, Carole-Ann Huppé, David Gendron, Marie-Renée Blanchet
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 44:50-56
Fibrosis complicates numerous pathologies including interstitial lung diseases. Sphingosine analogs such as FTY720 can alleviate lung injury-induced fibrosis in murine models. Contradictorily, FTY720 also promotes in vitro processes normally leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6def62b8571a202b2dd3cf757764ce
https://doi.org/10.1016/j.pupt.2017.03.010
https://doi.org/10.1016/j.pupt.2017.03.010
Publikováno v:
The Journal of Immunology. 204:234.12-234.12
Hypersensitivity pneumonitis (HP) is a TH1/TH17-polarized chronic disease caused by repetitive exposure to airborne agents. Efficient acquired B cell responses are thought to sustain pulmonary inflammation in HP. We found that an S1P1 pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3c2fb6d37be3ea4e2abc00582b5127
https://doi.org/10.4049/jimmunol.204.supp.234.12
https://doi.org/10.4049/jimmunol.204.supp.234.12