Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Pascale Alard"'
Publikováno v:
Autoimmunity, Vol 53, Iss 6, Pp 323-332 (2020)
Although the relationship between autoimmunity and microorganisms is complex, there is evidence that microorganisms can prevent the development of various autoimmune diseases. Lactobacilli are beneficial gut bacteria that play an important role in im
Externí odkaz:
https://doaj.org/article/8be6ea4948814559a97e33211c2da488
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/0993825a5bb7447e918d126374a20fa1
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Regulatory T cells (Tregs) play a critical role in controlling autoreactive T cells, and quantitative and/or qualitative deficiencies in Tregs are associated with autoimmune diseases, including type 1 diabetes (T1D), in both humans and mice. Both the
Externí odkaz:
https://doaj.org/article/c0403eaf55ac4d0c9bd388bf8c3950f5
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
Dendritic cells (DCs) from NOD mice produced high levels of IL-12 that induce IFNγ-producing T cells involved in diabetes development. We propose to utilize the microorganism ability to induce tolerogenic DCs to abrogate the proinflammatory process
Externí odkaz:
https://doaj.org/article/2b00b80485ad44f5930b0c2fbab45849
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3739 (2008)
BACKGROUND: Defects in APC and regulatory cells are associated with diabetes development in NOD mice. We have shown previously that NOD APC are not effective at stimulating CD4(+)CD25(+) regulatory cell function in vitro. We hypothesize that failure
Externí odkaz:
https://doaj.org/article/ed2fd53f6af84befb4be0229b3da1966
Autor:
James W Harder, Jing Ma, Pascale Alard, Kevin J Sokoloski, Edith Mathiowitz, Stacia Furtado, Nejat K Egilmez, Michele M Kosiewicz
Publikováno v:
Journal of Leukocyte Biology. 113:41-57
Systemic lupus erythematosus development is influenced by both sex and the gut microbiota. Metabolite production is a major mechanism by which the gut microbiota influences the immune system, and we have previously found differences in the fecal meta
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Autor:
Pascale Alard
Publikováno v:
The Journal of Immunology. 208:106.15-106.15
Students' ability to retrieve acquired knowledge long-term is critical for every discipline. The research on learning shows undergraduate students use ineffective learning strategies, misjudging passive vs active ways of learning, and prioritizing gr
Publikováno v:
The Journal of Immunology. 208:158.11-158.11
Hormones and gut microbiota affect lupus. In female NZBxNZW1(BWF1) mice, androgen treatment abrogates lupus; castration/treatment with androgen receptor blocker (flutamide) induces disease in BWF1 male mice. Gut microbiota alterations have been repor
Publikováno v:
Autoimmunity. 53(6)
Although the relationship between autoimmunity and microorganisms is complex, there is evidence that microorganisms can prevent the development of various autoimmune diseases. Lactobacilli are beneficial gut bacteria that play an important role in im