Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pascale Aeschlimann"'
Autor:
Reidun Stenberg, Marios Hadjivassiliou, Pascale Aeschlimann, Nigel Hoggard, Daniel Aeschlimann
Publikováno v:
Autoimmune Diseases, Vol 2014 (2014)
Objectives. We have previously reported a high prevalence of gluten-related serological markers (GRSM) in children and young adults with cerebral palsy (CP). The majority had no enteropathy to suggest coeliac disease (CD). Antibodies against transglu
Externí odkaz:
https://doaj.org/article/1c135fc05d5f4df2a06d7c29bbc860dd
Autor:
Charles Martin Heard, Andrea Brancale, Carmine Varricchio, Pascale Aeschlimann, Kathy Beirne, Marcela Votruba, Malgorzata Barbara Rozanowska
Publikováno v:
Journal of medicinal chemistry. 63(22)
Leber’s hereditary optic neuropathy (LHON) is a rare genetic mitochondrial disease and the primary cause of chronic visual impairment for at least 1 in 10 000 individuals in the U.K. Treatment options remain limited, with only a few drug candidates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c8f82228cf571cfd508c56d91378cf
https://pubmed.ncbi.nlm.nih.gov/33180495
https://pubmed.ncbi.nlm.nih.gov/33180495
Publikováno v:
Nutrients
Volume 12
Issue 9
Nutrients, Vol 12, Iss 2884, p 2884 (2020)
Volume 12
Issue 9
Nutrients, Vol 12, Iss 2884, p 2884 (2020)
Dermatitis herpetiformis (DH) is an extraintestinal manifestation of gluten sensitivity, in which an autoimmune response is directed against transglutaminase 3 (TG3), an epidermal transglutaminase. TG2 is the autoantigen in celiac disease (CD), defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be270dac2b7dd38ec2a2d5ab7a3055c6
https://orca.cardiff.ac.uk/id/eprint/134859/4/nutrients-12-02884.pdf
https://orca.cardiff.ac.uk/id/eprint/134859/4/nutrients-12-02884.pdf
Autor:
Daniel Aeschlimann, Pascale Aeschlimann, Priya D. Shanmugarajah, Markus Reuber, Nigel Hoggard, Stephen Howell, Richard A. Grünewald, Gary Dennis, Marios Hadjivassiliou
Purpose\ud \ud \ud Phenytoin is an effective anticonvulsant for focal epilepsy. Its use can be associated with long-term adverse effects including cerebellar ataxia. Whilst phenytoin is toxic to Purkinje cells in vitro; the clinical and radiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d029e72f3fb999f4a7230afbec7077
Autor:
Stefano Martelossi, Nicola Salce, Tarcisio Not, Fabiana Ziberna, Pascale Aeschlimann, Giorgio Cozzi, Daniel Aeschlimann, Luigina De Leo, Serena Vatta, Alessandro Ventura, Marios Hadjivassiliou
Objectives: Antibodies against transglutaminase 6 (anti-TG6) have been implicated in neurological manifestations in adult patients with genetic-gluten intolerance and it is unclear whether autoimmunity to TG6 develops following prolonged gluten expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eac540a87dc2ebbd2b0d0c0986e64d
Autor:
Ptolemaios G. Sarrigiannis, Pascale Aeschlimann, Richard A. Grünewald, Daniel Aeschlimann, Marios Hadjivassiliou, David S Sanders, Dasappaiah Ganesh Rao, Panagiotis Zis
Publikováno v:
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 49(11)
BACKGROUND: \ud \ud TG6 antibodies have been shown to be a marker of gluten ataxia but their presence in the context of other neurological manifestations of gluten sensitivity has not been explored. We investigated the presence of TG6 antibodies in g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a64bb1baf1d0344b2a4d6b2d6003c63
https://pubmed.ncbi.nlm.nih.gov/28886934
https://pubmed.ncbi.nlm.nih.gov/28886934
Autor:
Udai Bhan Pandey, Alexandra Durr, Debasmita Tripathy, Beatrice Vignoli, Christopher D. Stephen, Nandini Ramesh, María José Polanco, Maria Pennuto, Daniel Aeschlimann, Marie-Lorraine Monin, Manuela Basso, Marios Hadjivassiliou, Pascale Aeschlimann, Marco Canossa, Shannon Turberville, Marie Coutelier, Jeremy D. Schmahmann
Spinocerebellar ataxia type 35 (SCA35) is a rare autosomal-dominant neurodegenerative disease caused by mutations in the TGM6 gene, which codes for transglutaminase 6 (TG6). Mutations in TG6 induce cerebellar degeneration by an unknown mechanism. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8129991d1da3edbedb20e543351fdd1f
http://hdl.handle.net/11577/3257854
http://hdl.handle.net/11577/3257854
Autor:
Gail Haddock, Katri Kaukinen, Richard Grünewald, Oliver Bandmann, David S Sanders, Pascale Aeschlimann, Daniel Aeschlimann, Nicola Woodroofe, Markku Mäki, Marios Hadjivassiliou
Publikováno v:
Neurology. 80:1740-1745
Objectives: The previous finding of an immunologic response primarily directed against transglutaminase (TG)6 in patients with gluten ataxia (GA) led us to investigate the role of TG6 antibodies in diagnosing GA. Methods: This was a prospective cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b762555d4a02a62df876b167aacdb029
https://doi.org/10.1212/wnl.0b013e3182919070
https://doi.org/10.1212/wnl.0b013e3182919070
Autor:
Konrad Beck, Magdalena Adamczyk, Pascale Aeschlimann, Martin Hils, Daniel Aeschlimann, Helen Thomas, Lars Thiebach, Radu C. Oita, Martin Simon Langley
Publikováno v:
Amino Acids
Transglutaminases (TG) form a family of enzymes that catalyse various post-translational modifications of glutamine residues in proteins and peptides including intra- and intermolecular isopeptide bond formation, esterification and deamidation. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6dd8a628fba0e8578ccc3b851ca72c0
https://doi.org/10.1007/s00726-011-1091-z
https://doi.org/10.1007/s00726-011-1091-z
Autor:
Hui Jer Hwang, Edgardo Smecuol, Eduardo Mauriño, Horacio Vázquez, Walter L. Binder, Pascale Aeschlimann, Julio C. Bai, Daniel Aeschlimann, Roberto M. Mazure, Sonia I. Niveloni, Emilia Sugai
Publikováno v:
Clinical Chemistry. 56:661-665
Background: Some patients with celiac disease (CD) may be seronegative with the commonly used test for IgA anti–tissue transglutaminase (anti-tTG) antibodies. Our aim was to explore whether newer assays incorporating synthetic deamidated gliadin-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca55f6802dcdd9020e0dbf0b8e4d3bf
https://doi.org/10.1373/clinchem.2009.129668
https://doi.org/10.1373/clinchem.2009.129668