Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Pascale, Vicat"'
Autor:
Delphine Valente, Christine Mauriac, Thorsten Schmidt, Ingo Focken, Jochen Beninga, Brian Mackness, Huawei Qiu, Pascale Vicat, Abdullah Kandira, Katarina Radošević, Srini Rao, John Darbyshire, Mostafa Kabiri
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Monoclonal antibodies (mAbs) are among the fastest growing and most effective therapies for myriad diseases. Multispecific antibodies are an emerging class of novel therapeutics that can target more than one tumor- or immune-associated modulators per
Externí odkaz:
https://doaj.org/article/131fb11c1c2b4c5080fd734830439d0d
Publikováno v:
Internet of Things
Internet of Things, 2023, pp.100678. ⟨10.1016/j.iot.2023.100678⟩
Internet of Things, 2023, pp.100678. ⟨10.1016/j.iot.2023.100678⟩
International audience; The last decade has seen the explosion of the Internet of Things (IoT), which is enabling a range of new applications based on the connection of physical objects to the Internet. The growing diversity of IoT connectivity techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4021069cf769566023482dfa58f7cef
https://hal.science/hal-03952008/document
https://hal.science/hal-03952008/document
Autor:
Samir Si-Mohammed, Malasri Janumporn, Thomas Begin, Isabelle Guérin Lassous, Pascale Vicat-Blanc
Publikováno v:
Latin America Networking Conference
Latin America Networking Conference, Oct 2022, Armenia, Colombia. ⟨10.1145/3545250.3560845⟩
Latin America Networking Conference, Oct 2022, Armenia, Colombia. ⟨10.1145/3545250.3560845⟩
International audience; With the tremendous ascension of the Internet of Things over the recent years, ns-3 has consolidated its position in terms of popularity among the research community. Indeed, it has become one of the most used open-source netw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c99f842151c162959da6f807337dc88
https://hal.science/hal-03822142
https://hal.science/hal-03822142
Autor:
Mark P. Grillo, Svetlana Markova, Marc Evanchik, Marc Trellu, Patricia Moliner, Priscilla Brun, Anne Perreard-Dumaine, Pascale Vicat, Chun Yang, James P. Driscoll, Tim J. Carlson
Publikováno v:
Xenobiotica. 51:222-238
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator de...
Autor:
Chrystelle Girardet, Magali Mathieu, François Vallée, Jacques Le-Roux, Fangxian Sun, Laurence Fabien, Corinne Terrier, Celine Ginesty, Bruno Filoche-Romme, Florence Gruss-Leleu, Maysoun Shomali, Monsif Bouaboula, Sylvie Beccari, Pascal Desmazeau, Gilles Lebourg, Tsiala Benard, Victor Certal, Pascale Vicat, Andrew Hebert, Carlos Garcia-Echeverria, Laurent Schio, Youssef El-Ahmad, Gary Mccort, Claire Muller, Maurice Brollo, Mikhail Levit, Luc Bertin, Hong Cheng, Véronique Loyau, Valerie Steier, Fabienne Thompson, Audrey Louboutin, Fabienne Pilorge, Alexey Rak, Frank Halley, Patrick Richepin, Christelle Perrault, Pierre-Yves Abecassis, Michel Tabart, Albane Courjaud
Publikováno v:
Journal of Medicinal Chemistry. 63:512-528
More than 75% of breast cancers are estrogen receptor alpha (ERα) positive (ER+), and resistance to current hormone therapies occurs in one-third of ER+ patients. Tumor resistance is still ERα-dependent, but mutations usually confer constitutive ac
Autor:
Nadine Michot, Aurélia Guyochin, Mathieu Cinier, Chloé Savignard, Olivier Kitten, Marie-Hélène Pascual, Stéphanie Pouzieux, Marie-Laure Ozoux, Patrick Verdier, Pascale Vicat, Jacques Dumas
Publikováno v:
Peptides. 152
A new strategy of peptide half-life extension has been evaluated. We investigated libraries of a small and very stable protein scaffold called Nanofitin, capable of high affinity for protein targets. We have identified Nanofitins targeting Human and
Autor:
Mark P, Grillo, Svetlana, Markova, Marc, Evanchik, Marc, Trellu, Patricia, Moliner, Priscilla, Brun, Anne, Perreard-Dumaine, Pascale, Vicat, James P, Driscoll, Tim J, Carlson
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(2)
Dilated cardiomyopathy (DCM) is a disease of the myocardium defined by left ventricular enlargement and systolic dysfunction leading to heart failure. Danicamtiv, a new targeted myosin activator designed for the treatment of DCM, was characterised in
Autor:
Franziska Graf, Wolfgang Mück, Dominique Swerts, Kerstin J. Frank, Dorina van der Mey, Joanne Bennett, Marta Venczel, Thomas Müller, Uwe Muenster, Hans Lennernäs, Florent Mazuir, Jan Bevernage, Mei Wong, Mark McAllister, Stéphane Beilles, Loic Laplanche, Alison Margolskee, Stefania Beato, Lieve Adriaenssen, Loeckie de Zwart, Jonas Angstenberger, Xavier Pepin, Anh-Thu Nguyen-Trung, Alexander Marker, Amin Rostami-Hodjegan, P. Zane, Céline Ollier, An Van Den Bergh, Adam S. Darwich, Shriram M. Pathak, Dónal Murphy, Markus Kolhmann, Pankaj Daga, Susanne Greschat-Schade, Michael B. Bolger, Achiel Van Peer, Christer Tannergren, Priscilla Brun, Mohammed Yasin, Bertil Abrahamsson, Sara Carlert, Richard Lloyd, Christophe Tistaert, Leon Aarons, Petra Loos, Xavier Boulenc, Pascale Vicat
Publikováno v:
Margolskee, A, Darwich, A, Pepin, X, Pathak, S M, Bolger et al, M B, Aarons, L, Rostami-Hochaghan, A, Angstenberger, J, Graf, F, Laplanche, L, Muller, T, Carlert, S, Daga, P, Murphy, D, Tannergren, C, Yasin, M, Greschat-Schade, S, Muck, W, Muenster, U, van der Mey, D, Frank, K, Lloyd, R, Adriaenssen, L, Bevernage, J, De Zwart, L, Swerts, D, Tistaert, C, Van Den Bergh, A, Van Peer, A, Beato, S, Nguyen-Trung, A-T, Bennett, J, McAllister, M, Wong, M, Zane, P, Ollier, C, Vicat, P, Kolhmann, M, Marker, A, Brun, P, Mazuir, F, Beilles, S, Venczel, M, Boulenc, X, Loos, P, Lennernas, H & Abrahamsson, B 2016, ' IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds ', European Journal of Pharmaceutical Sciences . https://doi.org/10.1016/j.ejps.2016.09.027
Predicting oral bioavailability (Foral) is of importance for estimating systemic exposure of orally administered drugs. Physiologically-based pharmacokinetic (PBPK) modelling and simulation have been applied extensively in biopharmaceutics recently.
Publikováno v:
In Future Generation Computer Systems 2005 21(4):439-442
Publikováno v:
In Future Generation Computer Systems 2005 21(4):515-524