Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Pascale, Jespers"'
Autor:
Géraldine Hubesch, Céline Dewachter, Laura Chomette, Emeline Hupkens, Pascale Jespers, Grégory Vegh, Mathilde Doppler, Umair Sheikh Mohammad, Anaïs Thiriard, Myriam Remmelink, Jean‐Luc Vachiéry, Kathleen McEntee, Laurence Dewachter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 11 (2024)
Background Pulmonary hypertension and right ventricular (RV) dysfunction are major prognostic determinants in patients with heart failure with preserved ejection fraction (HFpEF). The underlying pathomechanisms remain unknown. In this context, we sou
Externí odkaz:
https://doaj.org/article/2cc8160322f04c6a8135d3c82c38a4cf
Autor:
Géraldine Hubesch, Aliénor Hanthazi, Angela Acheampong, Laura Chomette, Hélène Lasolle, Emeline Hupkens, Pascale Jespers, Grégory Vegh, Cécile Watu Malu Wembonyama, Caroline Verhoeven, Céline Dewachter, Jean-Luc Vachiery, Kathleen Mc Entee, Laurence Dewachter
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Heart failure with preserved ejection fraction (HFpEF) is a common complex clinical syndrome for which there are currently few evidence-based therapies. As patients with HFpEF very often present with comorbidities comprising the metabolic syndrome, w
Externí odkaz:
https://doaj.org/article/72de21e6cc9e4ec3b6d34eeb880b5479
Autor:
Céline Boudart, Fuhong Su, Lorenzo Pitisci, Arnaud Dhoine, Olivier Duranteau, Pascale Jespers, Antoine Herpain, Rebecca Vanderpool, Serge Brimioulle, Jacques Creteur, Robert Naeije, Luc Van Obbergh, Laurence Dewachter
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Sepsis is a common condition known to impair blood flow regulation and microcirculation, which can ultimately lead to organ dysfunction but such contribution of the coronary circulation remains to be clarified. We investigated coronary bl
Externí odkaz:
https://doaj.org/article/73a1ba16fb83406b885c71c9121e144f
Autor:
Bachar El Oumeiri, Philippe van deBorne, Géraldine Hubesch, Antoine Herpain, Filippo Annoni, Pascale Jespers, Constantin Stefanidis, Kathleen Mc Entee, Frédéric Vanden Eynden
Publikováno v:
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Abstract In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction. Thus, the objective of the present study was to evaluate the effects o
Externí odkaz:
https://doaj.org/article/a04d29878bb5443bb6e733829e0c4c84
Autor:
Aliénor Hanthazi, Pascale Jespers, Grégory Vegh, Christine Dubois, Géraldine Hubesch, Jean-Yves Springael, Laurence Dewachter, Kathleen Mc Entee
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundWhile chemerin has been shown to increase proliferation and migration of systemic vascular smooth muscle cells (SMCs) contributing therefore to the development of hypertension, this remains to be clarified for the pulmonary circulation.Meth
Externí odkaz:
https://doaj.org/article/53ac09584fad4acba14e55585c0c97a4
Autor:
Bachar, El Oumeiri, Philippe, van de Borne, Géraldine, Hubesch, Pascale, Jespers, Laurence, Dewachter, Constantin, Stefanidis, Kathleen, Mc Entee, Frédéric, Vanden Eynden
Publikováno v:
Journal of Basic and Clinical Physiology and Pharmacology. 33:743-750
Objectives Both N-terminal fragment of B-type natriuretic peptide (NT-proBNP) and soluble isoform of ST2 (sST2) have been identified as biomarkers of heart failure. We evaluated the plasma levels of NT-proBNP and sST2 in a rat model of severe aortic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d654a6ba2e0a5a2fd4ad0f9fe8a1df5e
https://doi.org/10.1515/jbcpp-2022-0215
https://doi.org/10.1515/jbcpp-2022-0215
Autor:
Bachar El Oumeiri, Laurence Dewachter, Philippe Van de Borne, Géraldine Hubesch, Christian Melot, Pascale Jespers, Constantin Stefanidis, Kathleen Mc Entee, Frédéric Vanden Eynden
Publikováno v:
Genes; Volume 14; Issue 1; Pages: 122
To explore the impact of omecamtiv mecarbil (OM) on the gene expression profile in adult male rats. Fourteen male Wistar rats were randomly assigned to a single OM (1.2 mg/kg/h; n = 6) or placebo (n = 8) 30-min infusion. Echocardiography was performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff681662f0f56ecce0a014dd6cc3df2f
Autor:
Samantha Gomart, Caroline Gaudreau-Ménard, Pascale Jespers, Omer Gurkan Dilek, Emeline Hupkens, Aliénor Hanthazi, Robert Naeije, Christian Melot, Nathalie Labranche, Laurence Dewachter, Kathleen Mc Entee
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169205 (2017)
Decreased leptin-induced endothelium-dependent vasodilation has been reported in spontaneously hypertensive rats (SHR). Here, we report leptin-induced vasoconstriction in endothelium-denuded pulmonary artery and thoracic aorta from SHR and sought to
Externí odkaz:
https://doaj.org/article/6fd423b311b74f6b8a4b8f42d3a866ec
Autor:
Géraldine Hubesch, Aliénor Hanthazi, Angela Acheampong, Laura Chomette, Hélène Lasolle, Emeline Hupkens, Pascale Jespers, Grégory Vegh, Cécile Watu Malu Wembonyama, Caroline Verhoeven, Céline Dewachter, Jean-Luc Vachiery, Kathleen Mc Entee, Laurence Dewachter
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Heart failure with preserved ejection fraction (HFpEF) is a common complex clinical syndrome for which there are currently few evidence-based therapies. As patients with HFpEF very often present with comorbidities comprising the metabolic syndrome, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ee1f78a949f729e717dcb331c02efa
https://pubmed.ncbi.nlm.nih.gov/35097026
https://pubmed.ncbi.nlm.nih.gov/35097026
Autor:
Constantin Stefanidis, Kathleen Mc Entee, Bachar Ghassan El Oumeiri, G. Hubesch, Philippe van de Borne, Pascale Jespers, Antoine Herpain, Filippo Annoni, Frédéric Vanden Eynden
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 16, Pp n/a-n/a (2021)
In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction. Thus, the objective of the present study was to evaluate the effects of the myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe31dd37b4d314844fba67abe22c2bf
https://doi.org/10.14814/phy2.14988
https://doi.org/10.14814/phy2.14988