Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Pascal Zihlmann"'
Autor:
Said Rabbani, Eva-Maria Krammer, Goedele Roos, Adam Zalewski, Roland Preston, Sameh Eid, Pascal Zihlmann, Martine Prévost, Marc F. Lensink, Andrew Thompson, Beat Ernst, Julie Bouckaert
Publikováno v:
IUCrJ, Vol 4, Iss 1, Pp 7-23 (2017)
The most prevalent diseases manifested by Escherichia coli are acute and recurrent bladder infections and chronic inflammatory bowel diseases such as Crohn's disease. E. coli clinical isolates express the FimH adhesin, which consists of a mannose-spe
Externí odkaz:
https://doaj.org/article/d86faef2f2ce48af946c95b24edbfd5b
Autor:
Wojciech Schönemann, Jonathan Cramer, Tobias Mühlethaler, Brigitte Fiege, Marleen Silbermann, Said Rabbani, Philipp Dätwyler, Pascal Zihlmann, Roman P. Jakob, Christoph P. Sager, Martin Smieško, Oliver Schwardt, Timm Maier, Beat Ernst
Publikováno v:
ChemMedChem. 14(7)
Antimicrobial resistance has become a serious concern for the treatment of urinary tract infections. In this context, an anti-adhesive approach targeting FimH, a bacterial lectin enabling the attachment of E. coli to host cells, has attracted conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70945bf7aa1a96e4bbab11414f60c8fa
https://pubmed.ncbi.nlm.nih.gov/30710416
https://pubmed.ncbi.nlm.nih.gov/30710416
Autor:
Said, Rabbani, Eva-Maria, Krammer, Goedele, Roos, Adam, Zalewski, Roland, Preston, Sameh, Eid, Pascal, Zihlmann, Martine, Prévost, Marc F, Lensink, Andrew, Thompson, Beat, Ernst, Julie, Bouckaert
Publikováno v:
IUCrJ
The role of the two tryrosine gating residues in the binding affinity of FimH for substituted mannosides is investigated using a combination of mutagenesis, X-ray crystallography, affinity measurements and molecular simulation. In contrast to the Y48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88897a0c35f037091b9105f92beb15a1
https://pubmed.ncbi.nlm.nih.gov/28250938
https://pubmed.ncbi.nlm.nih.gov/28250938