Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pascal Wassam"'
Publikováno v:
ACS Chemical Biology
Many small molecules, including bioactive molecules and approved drugs, spontaneously form colloidal aggregates in aqueous solution at micromolar concentrations. Though it is widely accepted that aggregation leads to artifacts in screens for ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba17d3dc00ee786b713495f158a14df
http://europepmc.org/articles/PMC3423826
http://europepmc.org/articles/PMC3423826
Autor:
Yiqun Cao, Brian K. Shoichet, Michael M. Mysinger, Pascal Wassam, Francesco Colizzi, Niu Huang, John J. Irwin
Publikováno v:
Journal of medicinal chemistry, vol 52, iss 18
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
Molecular docking is the most practical approach to leverage protein structure for ligand discovery, but the technique retains important liabilities that make it challenging to deploy on a large scale. We have therefore created an expert system, DOCK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9304c57bcc75939400377a967f84d42
https://escholarship.org/uc/item/1qc7f50n
https://escholarship.org/uc/item/1qc7f50n
Autor:
John J. Irwin, Brian K. Shoichet, Michael M. Mysinger, Niu Huang, Francesco Colizzi, Pascal Wassam, Yiqun Cao
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 18, p5712-5720, 9p
Autor:
Coleman, Ryan G.1, Carchia, Michael1, Sterling, Teague1, Irwin, John J.2, Shoichet, Brian K.1,2 bshoichet@gmail.com
Publikováno v:
PLoS ONE. Oct2013, Vol. 8 Issue 10, p1-19. 19p.
Autor:
Butterfoss, Glenn L., Yoo, Barney, Jaworski, Jonathan N., Chorny, Ilya, Dill, Ken A., Zuckermann, Ronald N., Bonneau, Richard, Kirshenbaum, Kent, Voelz, Vincent A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 09/04/2012, Vol. 109 Issue 36, p14320-14325, 6p
Publikováno v:
Biopolymers; 2011, Vol. 96 Issue 5, p639-650, 12p
Autor:
Pranav Deepak Pathak, Roshani Raut, Sebastian Jaramillo-Isaza, Pradnya Borkar, Rutvij H. Jhaveri
Volume 1 of Computational Approaches in Bioengineering—Computational Approaches in Biotechnology and Bioinformatics—explores many significant topics of biomedical engineering and bioinformatics in an easily understandable format. It explores rece