Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pascal Songhet"'
Autor:
Boas Felmy, Pascal Songhet, Emma Marie Caroline Slack, Andreas J Müller, Marcus Kremer, Laurye Van Maele, Delphine Cayet, Mathias Heikenwalder, Jean-Claude Sirard, Wolf-Dietrich Hardt
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77204 (2013)
Infections, microbe sampling and occasional leakage of commensal microbiota and their products across the intestinal epithelial cell layer represent a permanent challenge to the intestinal immune system. The production of reactive oxygen species by N
Externí odkaz:
https://doaj.org/article/cb67bbb77ab84a3e8351f239566f9945
Autor:
Benjamin Misselwitz, Naomi Barrett, Saskia Kreibich, Pascale Vonaesch, Daniel Andritschke, Samuel Rout, Kerstin Weidner, Milos Sormaz, Pascal Songhet, Peter Horvath, Mamta Chabria, Viola Vogel, Doris M Spori, Patrick Jenny, Wolf-Dietrich Hardt
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002810 (2012)
Targeting of permissive entry sites is crucial for bacterial infection. The targeting mechanisms are incompletely understood. We have analyzed target-site selection by S. Typhimurium. This enteropathogenic bacterium employs adhesins (e.g. fim) and th
Externí odkaz:
https://doaj.org/article/e24cb025b9064447ab282c36143cf5f1
Autor:
Pascal Songhet, Manja Barthel, Bärbel Stecher, Andreas J Müller, Marcus Kremer, Gunnar C Hansson, Wolf-Dietrich Hardt
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22459 (2011)
Enteropathogenic bacteria are a frequent cause of diarrhea worldwide. The mucosal defenses against infection are not completely understood. We have used the streptomycin mouse model for Salmonella Typhimurium diarrhea to analyze the role of interfero
Externí odkaz:
https://doaj.org/article/5daa2aeeda2546b694ac24c3e4c7b283
Autor:
Pascal Songhet, Manja Barthel, Till A Röhn, Laurye Van Maele, Delphine Cayet, Jean-Claude Sirard, Martin Bachmann, Manfred Kopf, Wolf-Dietrich Hardt
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13804 (2010)
Salmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes diarrhea and acute inflammation of the intestinal mucosa. The pro-inflammatory cytokines IL-17A and IL-17F are strongly induced in the infected mucosa but their contribution
Externí odkaz:
https://doaj.org/article/40b58373429a4828a167a5798ac77528
Autor:
Claudia Hoffmann, Marlies Galle, Sabrina Dilling, Rina Käppeli, Andreas J Müller, Pascal Songhet, Rudi Beyaert, Wolf-Dietrich Hardt
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12477 (2010)
The innate immune system is of vital importance for protection against infectious pathogens. Inflammasome mediated caspase-1 activation and subsequent release of pro-inflammatory cytokines like IL-1beta and IL-18 is an important arm of the innate imm
Externí odkaz:
https://doaj.org/article/ea02a99c51ab493798d227ed2484bc6a
Autor:
Nikki E. Freed, Martin Ackermann, Michael Doebeli, Bärbel Stecher, Wolf-Dietrich Hardt, Pascal Songhet
Publikováno v:
Nature. 454:987-990
In many biological examples of cooperation, individuals that cooperate cannot benefit from the resulting public good. This is especially clear in cases of self-destructive cooperation, where individuals die when helping others. If self-destructive co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea321c147b209373194fcf6aa1027fe
https://doi.org/10.1038/nature07067
https://doi.org/10.1038/nature07067
Publikováno v:
Developmental Dynamics. 236:633-643
Hematopoiesis in vertebrate development involves an embryonic, primitive wave and a later, definitive wave in which embryonic blood cells are replaced with adult blood cells. We here show that zebrafish fgf1 is involved in vivo in primitive hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcd704e784cde57543af391068bc1b6
https://doi.org/10.1002/dvdy.21056
https://doi.org/10.1002/dvdy.21056
Autor:
Nico van Rooijen, Laurye Van Maele, Delphine Fougeron, David Hot, Hans-Joachim Mollenkopf, Pascal Songhet, Delphine Cayet, Wolf-Dietrich Hardt, Arndt Benecke, Jean-Claude Sirard
Publikováno v:
Vaccine
Vaccine, 2015, 33 (29), pp.3331-41. ⟨10.1016/j.vaccine.2015.05.022⟩
Vaccine, Elsevier, 2015, 33 (29), pp.3331-41. ⟨10.1016/j.vaccine.2015.05.022⟩
Vaccine, 33(29), 3331-3341. Elsevier BV
Fougeron, D, Van Maele, L, Songhet, P, Cayet, D, Hot, D, van Rooijen, N, Mollenkopf, H J, Hardt, W D, Benecke, A G & Sirard, J C 2015, ' Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract ', Vaccine, vol. 33, no. 29, pp. 3331-3341 . https://doi.org/10.1016/j.vaccine.2015.05.022
Vaccine, 2015, 33 (29), pp.3331-41. ⟨10.1016/j.vaccine.2015.05.022⟩
Vaccine, Elsevier, 2015, 33 (29), pp.3331-41. ⟨10.1016/j.vaccine.2015.05.022⟩
Vaccine, 33(29), 3331-3341. Elsevier BV
Fougeron, D, Van Maele, L, Songhet, P, Cayet, D, Hot, D, van Rooijen, N, Mollenkopf, H J, Hardt, W D, Benecke, A G & Sirard, J C 2015, ' Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract ', Vaccine, vol. 33, no. 29, pp. 3331-3341 . https://doi.org/10.1016/j.vaccine.2015.05.022
The Toll-like receptor 5 (TLR5) agonist flagellin is an effective adjuvant for vaccination. Recently, we demonstrated that the adaptive responses stimulated by intranasal administration of flagellin and antigen were linked to TLR5 signaling in the lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe363defabe7a8094515a9197ecba29
https://www.hal.inserm.fr/inserm-01182907/file/Fougeron-Vaccine-2015.pdf
https://www.hal.inserm.fr/inserm-01182907/file/Fougeron-Vaccine-2015.pdf
Autor:
Wolf-Dietrich Hardt, Samuel Rout, Peter Horvath, Patrick Jenny, Kerstin Weidner, Miloš Šormaz, Doris M. Spori, Daniel Andritschke, Naomi Barrett, Pascale Vonaesch, Viola Vogel, Saskia Kreibich, Benjamin Misselwitz, Mamta Chabria, Pascal Songhet
Publikováno v:
PLoS Pathogens, 8 (7)
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 7, p e1002810 (2012)
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 7, p e1002810 (2012)
Targeting of permissive entry sites is crucial for bacterial infection. The targeting mechanisms are incompletely understood. We have analyzed target-site selection by S. Typhimurium. This enteropathogenic bacterium employs adhesins (e.g. fim) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f617c90ac7e1827043d07f3bfe0752e7
Autor:
Wolf-Dietrich Hardt, Patrick Kaiser, Andreas Müller, Marcus Kremer, Hans-Jörg Fehling, Sabine Haueter, Christa Zellweger, Kurt E.J. Dittmar, Pascal Songhet, Thomas C. Weber, Kathrin Endt
Publikováno v:
Cell host & microbe
Summary Salmonella Typhimurium causes diarrhea by infecting the epithelium and lamina propria of the intestinal mucosa and by secreting various effector proteins through type III secretion systems (TTSSs). However, the mechanisms by which Salmonella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c65bc72be795064e043126ea563ea3
https://pubmed.ncbi.nlm.nih.gov/22264510
https://pubmed.ncbi.nlm.nih.gov/22264510