Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Pascal Senn"'
Autor:
Romain Kohler, Marcella Pucci, Basile Landis, Pascal Senn, Pierre-Alexandre Poletti, Paolo Scolozzi, Seema Toso, Minerva Becker, Alexandra Platon
Publikováno v:
Tomography, Vol 10, Iss 5, Pp 727-737 (2024)
Purpose: The purpose of this study was to analyze the prevalence of and complications resulting from temporal bone fractures in adult and pediatric patients evaluated for cranio-facial trauma in an emergency setting. Methods: A retrospective blinded
Externí odkaz:
https://doaj.org/article/dce1628890f04233b4def15e14efb58c
Autor:
Andreas Frithioff, Kenneth Weiss, Martin Frendø, Pascal Senn, Peter Trier Mikkelsen, Daniel Sieber, Mads Sølvsten Sørensen, David Bue Pedersen, Steven Arild Wuyts Andersen
Publikováno v:
3D Printing in Medicine, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Background 3D-printed temporal bone models can potentially provide a cost-effective alternative to cadaver surgery that can be manufactured locally at the training department. The objective of this study was to create a cost-effective 3D-pri
Externí odkaz:
https://doaj.org/article/fad074060cac411c96ab72b71602982c
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 5, Pp 1575-1583 (2022)
Abstract Purpose We evaluated the clinical significance of magnetic resonance imaging (MRI) findings and their prognostic value for initial hearing loss and recovery in patients with sudden sensorineural hearing loss (SSNHL). Materials and Methods Th
Externí odkaz:
https://doaj.org/article/5e3069ddaa1c42409fa35b7ceac7fd4c
Autor:
Rebecca Sipione, Nicolas Liaudet, Francis Rousset, Basile N. Landis, Julien Wen Hsieh, Pascal Senn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12863 (2023)
One of the most prevalent causes of olfactory loss includes traumatic brain injury with subsequent shearing of olfactory axons at the level of the cribriform plate (anterior skull base). Scar tissue at this level may prevent axonal regrowth toward th
Externí odkaz:
https://doaj.org/article/b6943e2396804fcca050bb477dafc95e
Autor:
German Nacher-Soler, Antoine Marteyn, Natasha Barenzung, Stéphanie Sgroi, Karl-Heinz Krause, Pascal Senn, Francis Rousset
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
The reactive oxygen species (ROS)-generating enzyme NOX3 has recently been implicated in the pathophysiology of several acquired forms of sensorineural hearing loss, including cisplatin-, noise- and age-related hearing loss. NOX3 is highly and specif
Externí odkaz:
https://doaj.org/article/a0b63fc415a141ed9b378c83e6b2103b
Autor:
Francis Rousset, German Nacher-Soler, Vivianne Beatrix Christina Kokje, Stéphanie Sgroi, Marta Coelho, Karl-Heinz Krause, Pascal Senn
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of se
Externí odkaz:
https://doaj.org/article/f710c753abb547f2bc7d391150d33308
Autor:
Dominik Schmidbauer, Stefan Fink, Francis Rousset, Hubert Löwenheim, Pascal Senn, Rudolf Glueckert
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2013 (2023)
Neurotrophins promote neurite outgrowth of auditory neurons and may help closing the gap to cochlear implant (CI) electrodes to enhance electrical hearing. The best concentrations and mix of neurotrophins for this nerve regrowth are unknown. Whether
Externí odkaz:
https://doaj.org/article/551608dd135349f584c3e1f7b1fadb67
Autor:
Francis Rousset, Giulia Schilardi, Stéphanie Sgroi, German Nacher-Soler, Rebecca Sipione, Sonja Kleinlogel, Pascal Senn
Publikováno v:
Cells, Vol 11, Iss 15, p 2431 (2022)
Hearing loss affects over 460 million people worldwide and is a major socioeconomic burden. Both genetic and environmental factors (i.e., noise overexposure, ototoxic drug treatment and ageing), promote the irreversible degeneration of cochlear hair
Externí odkaz:
https://doaj.org/article/c66d491cdd084cf2b4bc9e9456e542f0
Autor:
German Nacher-Soler, Sébastien Lenglet, Marta Coelho, Aurélien Thomas, François Voruz, Karl-Heinz Krause, Pascal Senn, Francis Rousset
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Cisplatin is a lifesaving chemotherapeutic drug with marked ototoxic adverse effects. Cisplatin-induced hearing loss affects a significant part of cancer-surviving patients and is an unmet clinical need with important socioeconomic consequences. Unfo
Externí odkaz:
https://doaj.org/article/e1f544408a7c453ca2eb1b63b80cccef
Autor:
Francis Rousset, Patrick Salmon, Simon Bredl, Ophélie Cherpin, Marta Coelho, Renier Myburgh, Marco Alessandrini, Michael Perny, Marta Roccio, Roberto F. Speck, Pascal Senn, Karl Heinz Krause
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 351-363 (2019)
Synthetic microRNA (miRNA) minigenes (SMIGs) have a major potential for molecular therapy; however, their optimal architecture still needs to be determined. We have previously optimized the stem structure of miRNA hairpins for efficient gene knockdow
Externí odkaz:
https://doaj.org/article/9eaa2cb7bc0c4581aa060442360c4b87