Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Pascal Salin"'
Autor:
Pascal Salin, Christophe Melon, Carine Chassain, Paolo Gubellini, Guilhem Pages, Bruno Pereira, Yann Le Fur, Franck Durif, Lydia Kerkerian-Le Goff
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106398- (2024)
Parkinson's disease (PD) is characterized by the progressive and asymmetrical degeneration of the nigrostriatal dopamine neurons and the unilateral presentation of the motor symptoms at onset, contralateral to the most impaired hemisphere. We previou
Externí odkaz:
https://doaj.org/article/f532aefe6e8342799cab30034d5567d1
Autor:
Xavier Caubit, Paolo Gubellini, Pierre L. Roubertoux, Michèle Carlier, Jordan Molitor, Dorian Chabbert, Mehdi Metwaly, Pascal Salin, Ahmed Fatmi, Yasmine Belaidouni, Lucie Brosse, Lydia Kerkerian-Le Goff, Laurent Fasano
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract We previously linked TSHZ3 haploinsufficiency to autism spectrum disorder (ASD) and showed that embryonic or postnatal Tshz3 deletion in mice results in behavioral traits relevant to the two core domains of ASD, namely social interaction def
Externí odkaz:
https://doaj.org/article/f42ea17c170a459481b5c6c86e9f7f83
Autor:
Xavier Caubit, Paolo Gubellini, Pierre L. Roubertoux, Michèle Carlier, Jordan Molitor, Dorian Chabbert, Mehdi Metwaly, Pascal Salin, Ahmed Fatmi, Yasmine Belaidouni, Lucie Brosse, Lydia Kerkerian-Le Goff, Laurent Fasano
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/af551a6f600c474197372d5ae6fc349b
Autor:
Salimata Diagne Houndjo, Christophe Melon, Pascal Salin, Abdoulaye Samb, Fatou Bintou Sarr, Lydia Kerkerian-Le Goff, Sylviane Lortet
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100297- (2022)
Background: Voacanga africana (VOC) has been widely used for many years in the African traditional medicine system for the treatment of a wide range of diseases, including mental disorders but VOC has never been tested in vivo in the context of neuro
Externí odkaz:
https://doaj.org/article/ffa4385d20c144dc8cdf686161af0ac5
Autor:
Emilie Dinh, Thomas Rival, Alice Carrier, Noemi Asfogo, Olga Corti, Christophe Melon, Pascal Salin, Sylviane Lortet, Lydia Kerkerian-Le Goff
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-19 (2021)
Abstract TP53INP1 is a stress-induced protein, which acts as a dual positive regulator of transcription and of autophagy and whose deficiency has been linked with cancer and metabolic syndrome. Here, we addressed the unexplored role of TP53INP1 and o
Externí odkaz:
https://doaj.org/article/72bd4f54a75243e3a4b94615173dc04c
Autor:
Serena Corti, Remi Bonjean, Thomas Legier, Diane Rattier, Christophe Melon, Pascal Salin, Erik A. Toso, Michael Kyba, Lydia Kerkerian‐Le Goff, Flavio Maina, Rosanna Dono
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 725-742 (2021)
Abstract Enhancing the differentiation potential of human induced pluripotent stem cells (hiPSC) into disease‐relevant cell types is instrumental for their widespread application in medicine. Here, we show that hiPSCs downregulated for the signalin
Externí odkaz:
https://doaj.org/article/c49417db6b2e497583d507f331d2646d
Autor:
Maxime Assous, Laurence Had-Aissouni, Paolo Gubellini, Christophe Melon, Imane Nafia, Pascal Salin, Lydia Kerkerian-Le-Goff, Philippe Kachidian
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 69-81 (2014)
Parkinson's disease (PD) is characterized by the progressive degeneration of substantia nigra (SN) dopamine neurons, involving a multifactorial cascade of pathogenic events. Here we explored the hypothesis that dysfunction of excitatory amino acid tr
Externí odkaz:
https://doaj.org/article/f9212e5a83dc4c359b8cf011d1914827
Publikováno v:
La Nouvelle Revue du Travail, Vol 8 (2016)
Unemployment, which is a key social, economic and political concern for many Europeans, has been reaching peaks that it had never witnessed in the past for any sustained period of time in France or Southern Europe. The causes of this situation are wo
Externí odkaz:
https://doaj.org/article/3bce53ba2ed7494397ac28ea3c2fc525
Autor:
Vitaly Khaindrava, Pascal Salin, Christophe Melon, Michael Ugrumov, Lydia Kerkerian-Le-Goff, Annie Daszuta
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 284-291 (2011)
Chronic high frequency stimulation of the subthalamic nucleus (STN-HFS) efficiently alleviates motor symptoms of advanced Parkinson's disease (PD). Here, we looked for possible STN-HFS-induced changes on adult brain neurogenesis in the hippocampus an
Externí odkaz:
https://doaj.org/article/d57926e3180a44efb9daaf355a714e5d
Autor:
Emilie Lacombe, Vitaly Khaindrava, Christophe Melon, Abid Oueslati, Lydia Kerkerian-Le Goff, Pascal Salin
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 116-125 (2009)
Subthalamic nucleus high frequency stimulation (STN-HFS) efficiently alleviates l-DOPA-sensitive parkinsonian motor symptoms, but has no direct beneficial action on l-DOPA-induced dyskinesias (LID). Here, we provide evidence that anti-akinetic STN-HF
Externí odkaz:
https://doaj.org/article/d95e55f160bf4524a9a89a457de3629c