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Autor:
Heinz Baumann, Pascal S. Bailon, Chun-Fai Lai, Marlene Dembski, K. K. Morella, David White, Louis A. Tartaglia, Hongkyun Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 93:8374-8378
The leptin receptor (OB-R) is a single membrane-spanning protein that mediates the weight regulatory effects of leptin (OB protein). The mutant allele (db) of the OB-R gene encodes a protein with a truncated cytoplasmic domain that is predicted to be