Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Pascal Peraldi"'
Autor:
Marc Pujalte‐Martin, Amine Belaïd, Simon Bost, Michel Kahi, Pascal Peraldi, Matthieu Rouleau, Nathalie M. Mazure, Frédéric Bost
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1719-1738 (2024)
Metformin and IACS‐010759 are two distinct antimetabolic agents. Metformin, an established antidiabetic drug, mildly inhibits mitochondrial complex I, while IACS‐010759 is a new potent mitochondrial complex I inhibitor. Mitochondria is pivotal in
Externí odkaz:
https://doaj.org/article/f7c9b6087330477c926a0b2739689af4
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1928 (2022)
Breast adipose tissue (AT) participates in the physiological evolution and remodeling of the mammary gland due to its high plasticity. It is also a favorable microenvironment for breast cancer progression. However, information on the properties of hu
Externí odkaz:
https://doaj.org/article/6ef68debec1c4679a4e2d3e709b11b7e
Autor:
Nicole Arrighi, Claudine Moratal, Grégoire Savary, Julien Fassy, Nicolas Nottet, Nicolas Pons, Noémie Clément, Sandy Fellah, Romain Larrue, Virginie Magnone, Kevin Lebrigand, Nicolas Pottier, Claude Dechesne, Georges Vassaux, Christian Dani, Pascal Peraldi, Bernard Mari
Publikováno v:
Cells, Vol 10, Iss 7, p 1832 (2021)
Fibrosis is a deleterious invasion of tissues associated with many pathological conditions, such as Duchenne muscular dystrophy (DMD) for which no cure is at present available for its prevention or its treatment. Fibro-adipogenic progenitors (FAPs) a
Externí odkaz:
https://doaj.org/article/cdb7303874f544cd8594f9bec4dc253f
Autor:
Faustine Pastor, Karine Dumas, Marie-Astrid Barthélémy, Claire Regazzetti, Noémie Druelle, Pascal Peraldi, Mireille Cormont, Jean-François Tanti, Sophie Giorgetti-Peraldi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract In response to endotoxemia, the organism triggers an inflammatory response, and the visceral adipose tissue represents a major source of proinflammatory cytokines. The regulation of inflammation response in the adipose tissue is thus of cruc
Externí odkaz:
https://doaj.org/article/ef7e6eae90454a8ba2c1f73c9ea64b63
Autor:
Bérengère Chignon-Sicard, Magali Kouidhi, Xi Yao, Audrey Delerue-Audegond, Phi Villageois, Pascal Peraldi, Patricia Ferrari, Yves Rival, David Piwnica, Jérôme Aubert, Christian Dani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Autologous fat grafting is a gold standard therapy for soft tissue defects, but is hampered by unpredictable postoperative outcomes. Fat graft enrichment with adipose-derived stromal cell (ASCs) was recently reported to enhance graft surviva
Externí odkaz:
https://doaj.org/article/932ca9fe73ea48d8bbb07ffc6ae4ba71
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 40 (2021)
Adipose tissue resides in specific depots scattered in peripheral or deeper locations all over the body and it enwraps most of the organs. This tissue is always in a dynamic evolution as it must adapt to the metabolic demand and constraints. It exhib
Externí odkaz:
https://doaj.org/article/1f11b8cca6074dfdb769e480b10c6a85
Publikováno v:
Cells, Vol 9, Iss 10, p 2251 (2020)
Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shap
Externí odkaz:
https://doaj.org/article/26605ecd769440d49a85f9c982b2b31c
Autor:
Claire Regazzetti, Karine Dumas, Yannick Le Marchand-Brustel, Pascal Peraldi, Jean-François Tanti, Sophie Giorgetti-Peraldi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52154 (2012)
REDD1 (Regulated in development and DNA damage response 1) is a hypoxia and stress response gene and is a negative regulator of mTORC1. Since mTORC1 is involved in the negative feedback loop of insulin signaling, we have studied the role of REDD1 on
Externí odkaz:
https://doaj.org/article/90d120c1fadd4297b6763bbc94a3f677
Autor:
Magali Plaisant, Sophie Giorgetti-Peraldi, Marike Gabrielson, Agnes Loubat, Christian Dani, Pascal Peraldi
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16798 (2011)
Human mesenchymal stem cells (hMSC) have the ability to differentiate into osteoblasts, adipocytes and chondrocytes. We have previously shown that hMSC were endowed with a basal level of Hedgehog signaling that decreased after differentiation of thes
Externí odkaz:
https://doaj.org/article/b3f91662e1404d1a88c2f4da9e6dea70
Autor:
Karine Dumas, Pascal Peraldi, Faustine Pastor, Chaima Ayachi, Rodolphe Anty, Sandra Lacas-Gervais, Nathalie Vaillant, Stéphanie Patouraux, Philippe Gual, Albert Tran, Jean-François Tanti, Laurent Yvan-Charvet, Sophie Giorgetti-Peraldi, Mireille Cormont, François Bertrand Favier, Stéphanie Bonnafous, Jerome Gilleron
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (4), pp.5046-5060. ⟨10.1096/fj.201901799RR⟩
FASEB Journal, 2020, 34 (4), pp.5046-5060. ⟨10.1096/fj.201901799RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (4), pp.5046-5060. ⟨10.1096/fj.201901799RR⟩
FASEB Journal, 2020, 34 (4), pp.5046-5060. ⟨10.1096/fj.201901799RR⟩
International audience; Nonalcoholic fatty liver disease is a chronic liver disease which is associated with obesity and insulin resistance. We investigated the implication of REDD1 (Regulated in development and DNA damage response-1), a stress-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f26bfdc94c595e82edd61f738b0c2c
https://doi.org/10.1096/fj.201901799rr
https://doi.org/10.1096/fj.201901799rr