Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Pascal M W Drake"'
Autor:
Jonathan Menary, Matthew Hobbs, Sara Mesquita de Albuquerque, Agata Pacho, Pascal M W Drake, Alison Prendiville, Julian K-C Ma, Sebastian S Fuller
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229952 (2020)
Plant molecular farming (PMF) is a convenient and cost-effective way to produce high-value recombinant proteins that can be used in the production of a range of health products, from pharmaceutical therapeutics to cosmetic products. New plant breedin
Externí odkaz:
https://doaj.org/article/0a4c287ad4544298b6ca876012ab6109
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229877 (2020)
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta expre
Externí odkaz:
https://doaj.org/article/490ccf5a082c4302b73563577e37ef2c
Autor:
Ilaria Pepponi, Elena Stylianou, Craig van Dolleweerd, Gil Reynolds Diogo, Matthew J Paul, Pascal M W Drake, Julian K-C Ma, Rajko Reljic
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60855 (2013)
Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immuno
Externí odkaz:
https://doaj.org/article/a54955682eab410c875dfcb51483f5c1
Autor:
Andy C. Tran, Gil R. Diogo, Matthew J. Paul, Alastair Copland, Peter Hart, Nickita Mehta, Edward. B. Irvine, Tufária Mussá, Pascal M. W. Drake, Juraj Ivanyi, Galit Alter, Rajko Reljic
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
New evidence has been emerging that antibodies can be protective in various experimental models of tuberculosis. Here, we report on protection against multidrug-resistant Mycobacterium tuberculosis (MDR-TB) infection using a combination of the human
Externí odkaz:
https://doaj.org/article/571ab20885874bdbbf5051fa15c6f248
Autor:
Tim H, Szeto, Pascal M W, Drake, Audrey Y-H, Teh, Nicole, Falci Finardi, Ashleigh G, Clegg, Mathew J, Paul, Rajko, Reljic, Julian K-C, Ma
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2480
Nicotiana tabacum (the tobacco plant ) has numerous advantages for molecular farming, including rapid growth, large biomass and the possibility of both cross- and self-fertilization. In addition, genetic transformation and tissue culture protocols fo
Autor:
Tim H. Szeto, Pascal M. W. Drake, Audrey Y-H. Teh, Nicole Falci Finardi, Ashleigh G. Clegg, Mathew J. Paul, Rajko Reljic, Julian K-C. Ma
Publikováno v:
Recombinant Proteins in Plants ISBN: 9781071622407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fe4cec7c45cdbad9e77ff114a4bdec
https://doi.org/10.1007/978-1-0716-2241-4_2
https://doi.org/10.1007/978-1-0716-2241-4_2
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229877 (2020)
PLoS ONE
PLoS ONE
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta expre
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Autor:
Gil R. Diogo, Szymon Stelter, Pascal M. W. Drake, Peter Hart, Matthew J. Paul, Alastair Copland, Craig J. van Dolleweerd, Rajko Reljic, Derek C. Macallan, Adam Sparrow
Publikováno v:
Cytokine
IL-4 is a pleiotropic cytokine that is highly Th2 polarizing. The ratio of IL-4 and its splice variant IL-4Δ2 observed in human health and disease suggests a role for both isoforms. In the present study, the biological function of murine IL-4Δ2 and
Publikováno v:
British Journal of Clinical Pharmacology. 83:82-87
Biotechnology has transformed the potential for plants to be a manufacturing source of pharmaceutical compounds. Now, with transgenic and transient expression techniques, virtually any biologic, including vaccines and therapeutics, could be manufactu